Patents by Inventor Walter E. Stalzer

Walter E. Stalzer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Continuous process for the preparation of fructopyranose sulfamate derivatives
    Patent number: 7196209
    Abstract: The present invention is directed to a continuous process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) wherein R1, R3, R4, R5, R6 and X are as herein defined. The present invention is further directed to a continuous process for the preparation of Topiramate.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: March 27, 2007
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Thomas W. Adkins, Charles F. Cicco, Penina Feibush, Donald A. Koch, Cynthia Maryanoff, Walter E. Stalzer
  • Continuous process for the preparation of fructopyranose sulfamate derivatives
    Publication number: 20040158081
    Abstract: The present invention is directed to a continuous process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) 1
    Type: Application
    Filed: October 23, 2003
    Publication date: August 12, 2004
    Inventors: Thomas W. Adkins, Charles F. Cicco, Penina Feibush, Donald A. Koch, Cynthia Maryanoff, Walter E. Stalzer
  • TFPX synthesis
    Patent number: 6284933
    Abstract: A method of making TFPX using an SN2 type nucleophilic displacement reaction. The method includes reacting a nucleophilic fluorine molecule with a nonfluorinated-tetrahalo-p-xylene molecule. Exemplary nucleophilic fluorine molecules include, but are not limited to, CsF, KF, NaF and LiF. The nonfluorinated-tetrahalo-p-xylene molecules may include, &agr;,&agr;,&agr;′,&agr;′-tetrachloro-p-xylene, &agr;,&agr;,&agr;′,&agr;′-tetrabromo-p-xylene or &agr;,&agr;,&agr;′,&agr;′-tetraiodo-p-xylene. The reaction may be carried out in an open or closed container. Furthermore, the reaction may be carried out in the presence of a phase transfer catalyst. In certain embodiments, the reaction is carried in a substantially solvent-free environment.
    Type: Grant
    Filed: December 6, 1996
    Date of Patent: September 4, 2001
    Inventors: William R. Dolbier, Jr., Xiao X. Rong, Walter E. Stalzer