Patents by Inventor Wendy Chao

Wendy Chao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING OXYGENATED CHOLESTEROL SULFATE AND AT LEAST ONE OF POLYALKYLENE GLYCOL, CARBOXYMETHYL CELLULOSE AND POLYOXYLGLYCERIDE
    Publication number: 20220175798
    Abstract: Compositions comprising oxygenated cholesterol sulfates (OCS) are provided. The OCS is, for example, 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or 5-cholesten, 3, 25-diol, disulfate (25HCDS). The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure due to acetaminophen), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Application
    Filed: November 15, 2021
    Publication date: June 9, 2022
    Inventors: Andrew R. Miksztal, WeiQi Lin, Mee Jean Kim, Hongwei Wu, Min L. Lee, Wendy Chao
  • COMPOSITIONS COMPRISING OXYGENATED CHOLESTEROL SULFATE AND AT LEAST ONE OF POLYALKYLENE GLYCOL, CARBOXYMETHYL CELLULOSE AND POLYOXYLGLYCERIDE
    Publication number: 20200222430
    Abstract: Compositions comprising oxygenated cholesterol sulfates (OCS) are provided. The OCS is, for example, 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or 5-cholesten, 3, 25-diol, disulfate (25HCDS). The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure due to acetaminophen), high cholesterol/high lipids, and various inflammatory diseases and conditions.
    Type: Application
    Filed: August 1, 2017
    Publication date: July 16, 2020
    Inventors: Andrew R. Miksztal, WeiQi Lin, Mee Jean Kim, Hongwei Wu, Min L. Lee, Wendy Chao
  • ORAL DOSAGE FORM WITH DRUG COMPOSITION, BARRIER LAYER AND DRUG LAYER
    Publication number: 20200197315
    Abstract: The present disclosure provides dosage forms designed to deliver active pharmaceutical ingredients (APIs) in a controlled release manner. For instance, the present disclosure includes dosage forms with adequate time of onset of action and reduced lag times in the fed state. Such dosage forms find use in a variety of conditions where a rapid onset of action is desired followed by an extended release phase for the active agent, for example in the treatment of ADHD, pain or anxiety. In some cases, the dosage form includes a drug composition including a pharmacologically active agent, a barrier layer covering at least a portion of the drug composition, and a drug layer covering at least a portion of the barrier layer, wherein the drug layer includes the pharmacologically active agent. Related methods of making and administering the disclosed dosage forms are also provided.
    Type: Application
    Filed: July 5, 2017
    Publication date: June 25, 2020
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Yen-Fei Chen, Chin-Chih Chiang
  • ORAL PHARMACEUTICAL DOSAGE FORMS
    Publication number: 20200101021
    Abstract: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
    Type: Application
    Filed: September 3, 2019
    Publication date: April 2, 2020
    Applicant: DURECT CORPORATION
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael Zamloot
  • Oral Pharmaceutical Dosage Forms
    Publication number: 20190231702
    Abstract: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
    Type: Application
    Filed: December 19, 2018
    Publication date: August 1, 2019
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael Zamloot
  • Compositions with a rheological modifier to reduce dissolution variability
    Patent number: 10300142
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions are also provided.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: May 28, 2019
    Assignee: Durect Corporation
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Oral pharamaceutical dosage forms
    Patent number: 10206883
    Abstract: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: February 19, 2019
    Assignee: Durect Corporation
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael Zamloot
  • COMPOSITIONS WITH A RHEOLOGICAL MODIFIER TO REDUCE DISSOLUTION VARIABILITY
    Publication number: 20180339049
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions are also provided.
    Type: Application
    Filed: November 29, 2017
    Publication date: November 29, 2018
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Compositions with a Rheological Modifier to Reduce Dissolution Variability
    Publication number: 20180236078
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions and formulations are also provided.
    Type: Application
    Filed: January 16, 2018
    Publication date: August 23, 2018
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Oral Pharmaceutical Dosage Forms
    Publication number: 20180193275
    Abstract: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
    Type: Application
    Filed: December 12, 2017
    Publication date: July 12, 2018
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael Zamloot
  • Compositions with a rheological modifier to reduce dissolution variability
    Patent number: 9907851
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions and formulations are also provided.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: March 6, 2018
    Assignee: Durect Corporation
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Compositions with a rheological modifier to reduce dissolution variability
    Patent number: 9855333
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions are also provided.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: January 2, 2018
    Assignee: Durect Corporation
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Oral Pharmaceutical Dosage Forms
    Publication number: 20170319501
    Abstract: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
    Type: Application
    Filed: April 12, 2017
    Publication date: November 9, 2017
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael Zamloot
  • Compositions with a Rheological Modifier to Reduce Dissolution Variability
    Publication number: 20170209581
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions are also provided.
    Type: Application
    Filed: January 4, 2017
    Publication date: July 27, 2017
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Compositions with a Rheological Modifier to Reduce Dissolution Variability
    Publication number: 20170196978
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions and formulations are also provided.
    Type: Application
    Filed: December 15, 2016
    Publication date: July 13, 2017
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Oral pharmaceutical dosage forms
    Patent number: 9655861
    Abstract: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: May 23, 2017
    Assignee: DURECT CORPORATION
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael Zamloot
  • Oral pharmaceutical dosage forms
    Patent number: 9592204
    Abstract: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
    Type: Grant
    Filed: March 5, 2013
    Date of Patent: March 14, 2017
    Assignee: DURECT CORPORATION
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael Zamloot
  • Compositions with a rheological modifier to reduce dissolution variability
    Patent number: 9572885
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions are also provided.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: February 21, 2017
    Assignee: Durect Corporation
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Compositions with a rheological modifier to reduce dissolution variability
    Patent number: 9555113
    Abstract: The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions and formulations are also provided.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: January 31, 2017
    Assignee: Durect Corporation
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael S. Zamloot, Karl Bratin, Ravi M. Shanker
  • Oral Pharmaceutical Dosage Forms
    Publication number: 20160136102
    Abstract: Abuse-resistant oral dosage forms suitable for administration of pharmacologically active agents are provided.
    Type: Application
    Filed: July 13, 2015
    Publication date: May 19, 2016
    Inventors: Su Il Yum, Wendy Chao, Huey-Ching Su, Roger Fu, Michael Zamloot