Abstract: A lint/pet hair roller assembly includes a body supporting a tubular adhesive lint remover roll. The assembly includes a handle and a roll support. The roller support includes a cross-member transversely mounted on the handle and carrying a pair of outwardly extending legs. Roll support members are fixed or rotatably carried on the legs for supporting a lint roll. The legs, in one aspect, are moveably mounted in the cross-member and biased to a normal first spacing to support a lint roll, but extendable outward for movement of the lint roll relative to the legs. In another aspect, a telescoping lint roll support is normally biased to an extended position to support the lint roll, but is collapsible for movement of the support relative to the legs. Alternately, a dispenser is carried on the handle for dispensing fluid from a storage chamber. Alternately, an additional cleaning element is carried on the support.

Abstract: Described are syringe devices useful in delivering medical materials internally in patients. In certain embodiments, syringe devices of the invention include widening internal lumen to assist in effective delivery of substances therethrough, and/or curved barrel portions with curved lumens therein. In still further disclosed embodiments, syringe devices include adaptations to prevent compression of compressible carrier materials to be delivered therethrough, curved barrel portions with flexible plunger arms to track the curved barrel portions, barrel portions controllable in shape such as to introduce and remove curves, visible markings to denote the direction of deflection of syringe barrel portions, imagable markers located on the syringe barrel, a cooperating plunger apparatus, or both; or combinations of some or all of these features.

Abstract: The present invention provides an implant for use in fusing adjacent bony structures. The implant comprises at least one structural member combined with at least one flexible planar member to retain the at least one structural member to form the implant.

Abstract: The present invention relates to the design and composition of a depot implant for optimal delivery of growth factors to treat osteoporotic bone, in that such depot implant is constructed to be in a cylinder (rod) or sphere shape and have a natural or synthetic polymer scaffold with or without impregnated calcium phosphate particles. The density of the depot is higher than a typical BMP sponge carrier to facilitate it's implantation and slower release of the growth factor. The scaffold is such that it has adequate porosity and pore size to facilitate growth factor seeding and diffusion throughout the whole of the bone structure resulting in increased bone mineral density in the osteoporotic bone. In addition, the shape of the depot implant allows for delivery through a cannula or large bore needle.

Abstract: The invention provides compositions, kits, and methods for treatment of neuronal injury. In one embodiment, the composition comprises a biomembrane sealing agent, such as PEG, and a bioactive agent, such as a magnesium compound. The biomembrane sealing agent and/or the bioactive agent an intravenous administration, an intramuscular administration, an intrathecal administration, a subcutaneous administration, an epidural administration, a parenteral administration, a direct application onto or adjacent to a site of the pathological condition, and any combinations thereof. Alternatively, the biomembrane sealing agent and/or the bioactive agent may be delivered from a pump or an implant.

Abstract: The invention provides methods and kits for treatment of pain or inflammation. In one embodiment, the kit comprises a biomembrane sealing agent, such as PEG, and a bioactive agent, such as a magnesium compound. The biomembrane sealing agent and/or the bioactive agent an intravenous administration, an intramuscular administration, an intrathecal administration, a subcutaneous administration, an epidural administration, a parenteral administration, an intra-articular administration, a direct application onto or adjacent to a site of the pathological condition, and any combinations thereof. Alternatively, the biomembrane sealing agent and/or the bioactive agent may be delivered from a pump or an implant.

Abstract: Described are malleable medical compositions such as pastes or putties that include solids combined with a liquid carrier. The solids include particulate collagen and particulate demineralized bone matrix. The liquid carrier includes an aqueous medium comprising a polysaccharide. Also described are methods for making and using such medical compositions.

Abstract: Described are medical implant devices that include particulate collagen and particulate demineralized bone matrix. These and potentially other materials are held together in a three-dimensionally stable structure such as a porous, resilient sheet, by an ionically-crosslinked polysaccharide gel. Also described are methods for making and using such medical devices.

Abstract: An implant is insertable onto a vertebral facet joint includes a body with an inner surface that mates with one or both articular processes of the facet joint. The inner surface may define an interior cavity that accepts at least a portion of an inferior articular process and a superior articular process forming the facet joint. The body may be constructed of a bone growth material that fuses with the articular processes. The implant may help retain bone growth promoting substance that is inserted between or on articulating surfaces of the facet joint. A receiving portion of an exterior surface of one or both articular process may be prepared to stimulate bone growth. The implant may be placed onto the receiving portion to cover an exterior junction between or on the articulating surfaces of the facet joint. The implant may be secured to one or both of the articular processes.

Abstract: Methods and compositions are provided for reduction of inflammation and improved allograft/host tissue integration comprising placing at least one anti-inflammatory compound onto a site of the defect and placing a graft structure onto the site of the defect.

Abstract: The present invention relates to novel drug depot implant designs for optimal delivery of therapeutic agents to subjects. The invention provides a method for alleviating pain associated with neuromuscular or skeletal injury or inflammation by targeted delivery of one or more therapeutic agents to inhibit the inflammatory response which ultimately causes acute or chronic pain. Controlled and directed delivery can be provided by drug depot implants, comprising therapeutic agents, specifically designed to deliver the therapeutic agent to the desired location by facilitating their implantation, minimizing their migration from the desired tissue location, and without disrupting normal joint and soft tissue movement.

Abstract: The present invention relates to novel drug depot implant designs for optimal delivery of therapeutic agents to subjects. The invention provides a method for alleviating pain associated with neuromuscular or skeletal injury or inflammation by targeted delivery of one or more therapeutic agents to inhibit the inflammatory response which ultimately causes acute or chronic pain. Controlled and directed delivery can be provided by drug depot implants, comprising therapeutic agents, specifically designed to deliver the therapeutic agent to the desired location by facilitating their implantation, minimizing their migration from the desired tissue location, and without disrupting normal joint and soft tissue movement.

Abstract: An endovascular device includes a body having a surface, and at least one protein or peptide antagonist of calcification disposed on a portion of the surface. In another embodiment of the invention, an endoluminal device includes a body having a surface, and a coating disposed on a portion of the surface. The coating includes a transforming growth factor beta receptor antagonist. Another embodiment of the invention provides a method of inhibiting calcification of an endoluminal device. The method includes providing a body including a surface, disposing at least one protein or peptide antagonist of calcification on a portion of the surface, and deploying the body at a treatment site.

Abstract: A lint roll apparatus includes an orienting mechanism for orienting the free edge of the outermost sheet of a adhesive roll with a predetermined point on a roll support. Orientation is implemented by cooperating stop members on the roll and the roll support, by a slidable member on the roll support moveable into and out of engagement with a notch in the roll or a roll core, or a trigger activated moveable pin which is engagable with a stop member carried on the roll or roll support. A motor driven spindle rotates a cylinder on which the roll is mounted.

Abstract: Described is a medically useful article comprising a three-dimensional body including one or more implantable substances, wherein the body defines one or more reservoirs for receiving amounts of a biocompatible wetting liquid. In certain embodiments the body is disruptable upon wetting with the biocompatible liquid to form a conformable implantable material such as a putty, paste or more flowable wetted implant material. Also described are methods for manufacturing such medical materials, and methods for using such medical materials to treat patients.

Abstract: A method and apparatus for detecting stains, urine, odor and feces, and more particularly, the combination of a black light detector and a liquid reservoir and/or trigger pump dispensing vehicle for containing stain removing chemicals is provided. The black light is selectively and removably mounted or positioned in the body of the dispensing vehicle.

Abstract: A brush for hygienic purposes includes a handle with a lower and an upper portion and a head. The upper portion is sized and shaped to capture the head. Preferably the head is a removable cartridge and includes a flexible base with a plurality bristles and a pad with holes disposed over the bristles. The pad could be a foam or sponge matrix or could be a stack of sheets removable one at a time. Upper portion of the handle is curved to provide a predetermined shape to the head. Optionally, a vibrating device is incorporated in the brush so that the brush can be used as to massage the skin or scalp.

Abstract: Described is an implantable medical material comprising a malleable, cohesive, shape-retaining putty including mineral particles, insoluble collagen fibers and soluble collagen. The medical material can be used in conjunction with biologically active factors such as osteogenic proteins to treat bone or other tissue defects in patients.

Abstract: An improved cleaning tool is provided with a flexible connection between the head or spindle and the handle. The improved tool broadly includes a spindle or head, a handle and a flexible connection between the head and handle to permit relative pivotal movement therebetween and rubber bumpers to protect against scratching furniture. The flexible connection regulates relative movement between the spindle head in such a way that lateral movement is greater than the up and down movement.

Abstract: A cleaning apparatus includes a handle, a support coupled to the handle and a cleaning element mountable on the support. The support is fixed to the handle or is rotatably coupled to the handle for rotation by a drive motor mounted in the handle. The cleaning element may include bristles extending from a flexible mat fixed about the support of about a core mountable on the support. A cleaning sheet is windable about the support, the core or the cleaning element, including over and through the bristles, for dual cleaning action.