Patents by Inventor Xicheng Sun

Xicheng Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONCENTRATED INJECTABLE TRANEXAMIC ACID COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20230248643
    Abstract: Concentrated tranexamic acid compositions suitable for intramuscular administration via auto-injector are provided. Methods of treating non-compressible hemorrhage are also provided. Kits and auto-injectors comprising the tranexamic acid compositions are further provided.
    Type: Application
    Filed: February 8, 2023
    Publication date: August 10, 2023
    Inventors: Amir Genosar, Xicheng Sun, Melissa Varner
  • Antimycobacterial heterocyclic amides
    Patent number: 11655225
    Abstract: The present invention provides novel heterocylic amide compounds having useful antimycobacterial activity. Use of these compounds as pharmaceutical compositions and method of their production are also provided.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: May 23, 2023
    Assignee: CRESTONE, INC.
    Inventors: Joshua Day, James Graham, Thale Jarvis, Elizabeth Mcfaddin, Urs Ochsner, Xicheng Sun, Christina Wong
  • Novel Antimycobacterial Heterocyclic Amides
    Publication number: 20210002239
    Abstract: The present invention provides novel heterocylic amide compounds having useful antimycobacterial activity. Use of these compounds as pharmaceutical compositions and method of their production are also provided.
    Type: Application
    Filed: February 28, 2019
    Publication date: January 7, 2021
    Inventors: Joshua Day, James Graham, Elizabeth McFadden, Urs Ocshner, Xicheng Sun, Christina Wong
  • Substituted quinoline compounds as S-nitrosoglutathione reductase inhibitors
    Patent number: 9856219
    Abstract: The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: January 2, 2018
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
    Patent number: 9814700
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: November 14, 2017
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Chromone inhibitors of S-nitrosoglutathione reductase
    Patent number: 9717706
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: August 1, 2017
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Jan Wasley
  • S-nitrosoglutathione reductase inhibitors
    Patent number: 9707212
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: July 18, 2017
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu
  • Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents
    Publication number: 20170049750
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: November 8, 2016
    Publication date: February 23, 2017
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Novel Substituted Quinoline Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20160340312
    Abstract: The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: August 4, 2016
    Publication date: November 24, 2016
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
    Patent number: 9498466
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Grant
    Filed: October 26, 2015
    Date of Patent: November 22, 2016
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu
  • Novel Substituted Bicyclic Aromatic Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20160279117
    Abstract: The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: June 6, 2016
    Publication date: September 29, 2016
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Substituted quinoline compounds as S-nitrosoglutathione reductase inhibitors
    Patent number: 9433618
    Abstract: The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: September 6, 2016
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Novel Substituted Quinoline Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20160220556
    Abstract: The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: April 13, 2016
    Publication date: August 4, 2016
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Substituted bicyclic aromatic compounds as S-nitrosoglutathione reductase inhibitors
    Patent number: 9364481
    Abstract: The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: June 14, 2016
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Novel Substituted Bicyclic Aromatic Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20160108011
    Abstract: The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: December 21, 2015
    Publication date: April 21, 2016
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Substituted quinoline compounds as S-nitrosoglutathione reductase inhibitors
    Patent number: 9315462
    Abstract: The present invention is directed to novel quinoline compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: April 19, 2016
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Dihydropyrimidin-2(1H)-one compounds as -nitrosoglutathione reductase inhibitors
    Patent number: 9283229
    Abstract: The present invention is directed to novel dihydropyrimidin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: March 15, 2016
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu
  • Dihydropyridin-2(1H)-one compounds as -nitrosoglutathione reductase inhibitors and neurokinin-3 receptor antagonists
    Patent number: 9283213
    Abstract: The present invention is directed to novel dihydropyridin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors and/or Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: March 15, 2016
    Assignee: Nivalis Therapeutics, Inc.
    Inventors: Xicheng Sun, Jian Qiu
  • Novel Substituted Bicyclic Aromatic Compounds as S-Nitrosoglutathione Reductase Inhibitors
    Publication number: 20160067254
    Abstract: The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
    Type: Application
    Filed: November 18, 2015
    Publication date: March 10, 2016
    Inventors: Xicheng Sun, Jian Qiu, Adam Stout
  • Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents
    Publication number: 20160045477
    Abstract: The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
    Type: Application
    Filed: October 26, 2015
    Publication date: February 18, 2016
    Inventors: Jan Wasley, Gary J. Rosenthal, Xicheng Sun, Sarah Strong, Jian Qiu