Patents by Inventor Yuanwei Chen

Yuanwei Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidine Derivatives for Treatment of Hyperproliferative Disorders
    Publication number: 20110098301
    Abstract: Pyrimidine derivatives of formula pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are disclosed and claimed.
    Type: Application
    Filed: March 9, 2006
    Publication date: April 28, 2011
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian R. Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu
  • Benzylic glycoside derivatives and methods of use
    Patent number: 7838498
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Grant
    Filed: April 1, 2008
    Date of Patent: November 23, 2010
    Assignee: Theracos, Inc.
    Inventors: Yuanwei Chen, Yan Feng, Baihua Xu, Binhua Lv, Brian Seed, Michael J. Hadd, Huawei Cheng, Zelin Sheng, Min Xu, Congna Wang, Jiyan Du, Lili Zhang, Ge Xu, Yuelin Wu
  • Benzylbenzene derivatives and methods of use
    Patent number: 7838499
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: November 23, 2010
    Assignee: Theracos, Inc.
    Inventors: Yuanwei Chen, Huawei Cheng, Shengbin Li, Yuelin Wu, Yan Feng, Binhua Lv, Baihua Xu, Brian Seed, Michael J. Hadd, Yanli Song, Jiyan Du, Congna Wang, Jacques Y. Roberge
  • Glucose transport inhibitors and methods of use
    Patent number: 7803778
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: September 28, 2010
    Assignee: Theracos, Inc.
    Inventors: Yuanwei Chen, Yan Feng, Baihua Xu, Binhua Lv, Jiajia Dong, Brian Seed, Michael J. Hadd
  • Spiroheterocyclic glycosides and methods of use
    Patent number: 7795228
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Grant
    Filed: December 26, 2007
    Date of Patent: September 14, 2010
    Assignee: Theracos, Inc.
    Inventors: Michael J. Hadd, Yuanwei Chen, Yan Feng, Sengen Sen, Brian Seed
  • SUBSTITUTED PYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS
    Publication number: 20100075971
    Abstract: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
    Type: Application
    Filed: December 1, 2009
    Publication date: March 25, 2010
    Inventors: Jacques DUMAS, Wendy Lee, Yuanwei Chen, Lila Adnane, William J. Scott, Sharad Verma, Jianqing Chen, Zhi Chen, Lin Yi
  • PYRIMIDINE DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE DISORDERS
    Publication number: 20100075967
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Application
    Filed: August 28, 2009
    Publication date: March 25, 2010
    Applicant: BAYER PHARMACEUTICALS CORPORATION
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianging Chen, Brian R. Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin F. Hentemann, Ann-Marie Bullion, Manoj Patel
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Patent number: 7678804
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: March 16, 2010
    Assignee: Bayer Healthcare LLC
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian R. Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin F. Hentemann, Ann-Marie Bullion, Manoj Patel
  • DEUTERATED BENZYLBENZENE DERIVATIVES AND METHODS OF USE
    Publication number: 20100063141
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions that are affected by SGLT inhibition.
    Type: Application
    Filed: July 15, 2009
    Publication date: March 11, 2010
    Applicant: Theracos, Inc.
    Inventors: Brian Seed, Binhua LV, Jacques Y. Roberge, Yuanwei Chen, Kun Peng, Jiajia Dong, Baihua Xu, Jiyan Du, Lili Zhang, Xinxing Tang, Ge Xu, Yan Feng, Min Xu
  • Pyrimidine Derivatives
    Publication number: 20090286785
    Abstract: This invention relates to novel compounds (I) and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Application
    Filed: April 7, 2006
    Publication date: November 19, 2009
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Dhanapalan Nagarathnam, Yuanwei Chen, Wenlang Fu, Donald Bierer, Ming Wang, Michael Brands, Yamin Wang, Brian R. Bear
  • Pyrimidine Derivatives
    Publication number: 20090258888
    Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Application
    Filed: April 7, 2006
    Publication date: October 15, 2009
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Dhanapalan Nagarathnam, Yuanwei Chen, Wenlang Fu, Donald Bierer, Ming Wang, Michael Brands, Yamin Wang, Brian R. Bear, Aaron Schmitt, Eric Mull, David Miller, Jin Zhao
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Patent number: 7582646
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: September 1, 2009
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian R. Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin F. Hentemann, Ann-Marie Bullion, Manoj Patel
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Patent number: 7582645
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: September 1, 2009
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Julie A. Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yi, Yuanwei Chen, Jianqing Chen, Brian Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin F. Hentemann, Ann-Marie Bullion
  • Cyanopyridine derivatives useful in the treatment of cancer and other disorders
    Patent number: 7557129
    Abstract: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: July 7, 2009
    Assignee: Bayer Healthcare LLC
    Inventors: William J. Scott, Jacques Dumas, Stephen Boyer, Wendy Lee, Yuanwei Chen, Barton Phillips, Sharad Verma, Jianqing Chen, Zhi Chen, Jianmei Fan, Brian Raudenbush, Aniko Redman, Lin Yi, Qingming Zhu, Lila Adnane
  • BENZYLPHENYL CYCLOHEXANE DERIVATIVES AND METHODS OF USE
    Publication number: 20090156516
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Application
    Filed: December 11, 2008
    Publication date: June 18, 2009
    Inventors: Yuanwei Chen, Kun Peng, Lili Zhang, Binhua Lv, Baihua Xu, Jiajia Dong, Jiyan Du, Yan Feng, Ge Xu, Vasanthakumar Rajappan, Brian Seed
  • BENZYLBENZENE DERIVATIVES AND METHODS OF USE
    Publication number: 20090118201
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Application
    Filed: August 22, 2008
    Publication date: May 7, 2009
    Inventors: Yuanwei Chen, Huawei Cheng, Shengbin Li, Yuelin Wu, Yan Feng, Binhua Lv, Baihua Xu, Brian Seed, Michael J. Hadd, Yanli Song, Jiyan Du, Congna Wang, Jacques Y. Roberge
  • BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE
    Publication number: 20080242596
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Application
    Filed: April 1, 2008
    Publication date: October 2, 2008
    Applicant: Theracos, Inc.
    Inventors: Yuanwei Chen, Yan Feng, Baihua Xu, Binhua Lv, Brian Seed, Michael J. Hadd, Huawei Cheng, Zelin Sheng, Min Xu, Congna Wang, Jiyan Du, Lili Zhang, Ge Xu, Yuelin Wu
  • SPIROHETEROCYCLIC GLYCOSIDES AND MEHTODS OF USE
    Publication number: 20080182802
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Application
    Filed: December 26, 2007
    Publication date: July 31, 2008
    Inventors: Michael J. Hadd, Yuanwei Chen, Yan Feng, Sengen Sen, Brian Seed
  • GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE
    Publication number: 20070275907
    Abstract: Provided are compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The invention also provides pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by SGLT inhibition.
    Type: Application
    Filed: May 22, 2007
    Publication date: November 29, 2007
    Inventors: Yuanwei Chen, Yan Feng, Baihua Xu, Binhua Lv, Jiajia Dong, Brian Seed, Michael Hadd
  • Pyrimidine derivatives for treatment of hyperproliferative disorders
    Publication number: 20070117817
    Abstract: Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G?, and G? represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
    Type: Application
    Filed: October 8, 2004
    Publication date: May 24, 2007
    Applicant: Bayer Pharmaceuticals Corporation
    Inventors: Julie Dixon, Dhanapalan Nagarathnam, Lei Zhang, Chunguang Wang, Lin Yin, Yuanwei Chen, Jianqing Chen, Brian Bear, Michael Brands, Alexander Hillisch, Donald Bierer, Ming Wang, Wenlang Fu, Martin Hentemann, Ann-Marie Bullion