Abstract: A teat dip composition comprising from about 0.1% to about 2% iodine by weight of the composition on a formulation basis and from about 50% to about 99.9% propylene glycol by weight of the composition on a formulation basis, and a method of using such composition to treat mastitis.

Abstract: A liquid antimicrobial composition comprises: (1) a mixture of iodide anions and thiocyanate anions; (2) periodic acid or an alkali metal salt thereof; and (3) optionally, a peroxidase. The composition may be used as a microbicide, disinfectant or for suppressing or killing viruses or spores.

Abstract: Methods and topical pharmaceutical formulations are provided for the treatment of nail fungus (onychomycosis). The invention involves a pharmacologically active antifungal agent, plus a pharmaceutically acceptable base in a formulation having a pH of 7.5 to about 13.0, preferably about 8.0 to 11.5, and most preferably about 8.5 to 10.5. These basic formulations permeate the nail and are effective in treating fungal infections of the nail and surrounding tissues.

Abstract: The present invention is directed to frozen biocidal compositions. Specifically, the biocidal compositions comprise a frozen aqueous solution of a plurality of ions selected from the group consisting of halide and oxyhalide ions. The frozen biocidal compositions are useful in preserving or extending the shelf-life of perishable articles.

Abstract: An iodine complex concentrate containing (a) from about 0.5 to about 30% by weight of iodine; (b) from about 0.2 to about 14% by weight of an iodide component selected from the group consisting of iodide salt, iodide acid and mixtures thereof; and (c) from about 2% to about 85% by weight of a nonionic sugar surfactant selected from the group consisting of alkyl glucose esters, aldobionamides, gluconamides, glyceramides, glyceroglycolipids, polygydroxy fatty acid amides, alkyl polyglycosides having the general formula I: R1O(R2O)b(Z)a  I wherein R1 is a monovalent organic radical having from about 6 to about 30 carbon atoms; R2 is divalent alkylene radical having from 2 to 4 carbon atoms; Z is a saccharide residue having 5 or 6 carbon atoms; b is a number having a value from 0 to about 12; a is a number having a value from 1 to about 6, and mixtures thereof, all weights being based on the weight of the concentrate.

Abstract: A method is provided to take advantage of naturally occurring factors that influence gender selection in such a way as to create a bias to conceive a specific gender. This is accomplished by teaching a woman how to recognize the various stages of her menstrual cycle and how and when to use ovulation predictor reagent strips to accurately predict when ovulation will occur. Specific instructions are provided as to when a couple should engage in intercourse. The method for influencing the chances of conceiving a child of a selected gender includes the steps of following a selected diet; supplementing said diet with selected nutriceuticals; douching with a selected douche prior to intercourse; and selectively timing intercourse.

Abstract: Methods and topical pharmaceutical formulations are provided for the treatment of nail fungus (onychomycosis). The invention involves a pharmacologically active antifungal agent, plus a pharmaceutically acceptable base in a formulation having a pH of 7.5 to about 13.0, preferably about 8.0 to 11.5, and most preferably about 8.5 to 10.5. These basic formulations permeate the nail and are effective in treating fungal infections of the nail and surrounding tissues.

Abstract: The present invention relates to a biocidal composition, designed for the generation of chlorine dioxide, comprising at least one iodo-compound having at least one iodine atom and a source of chlorite ions. The molar ration of chlorite ions to iodine atoms is 2 or greater. The composition finds use in a variety of applications including methods of cleaning, sanitizing, deodorizing, and disinfecting various surfaces.

Abstract: An aqueous acidic lubricating composition for use in the mucosal areas of the human body, that provides at least 30 ppm of available iodine. There is also provided a method of treating vaginitis preventing STD and group B streptococcus.

Abstract: A pharmaceutical mixture and a method of its production of a therapeutic composition for blocking the HIV-1 and HIV-2 virus replication in the CD4+ cells of the human immune system in all stages of that viral infection, and in AIDS for the treatment of HIV in a patient in need of such treatment.

Abstract: The invention relates generally to a method which utilizes iodine as a broad spectrum microbicide wherein the active agent may be applied in nasal passages in the manner of a decongestant type nose spray. The spray is intended particularly for human use. It is to be applied in the event of known or suspected exposure of the individual to common cold virus, flu, or other infective microbial agents including for example, bacteria, viruses, rickettsia, and even mold and fungus. The active agent is based on an iodine solution and may also contain one or more of the following: sodium hypochlorite solution, or a solution of chlorine or hypochlorites plus a salt of chloride, bromide or iodide. Alternatively, the solution may further contain iodine and a bromine solution, or a solution of iodine, bromine plus a salt of chloride, bromide or iodide such as sodium chloride, zinc chloride, sodium bromide, zinc bromide, sodium iodide or zinc iodide.

Abstract: The invention discloses a natural treatment for ecto-parasitic infestation, particularly effective against lice be it head, body or pubic. A preferred gel composition includes a salt, a plant essence, and a pharmaceutically acceptable gelling agent. Besides gel, the composition designed for use on scalp hair may be formulated as a shampoo, a detangling spray conditioner, mousse, hair spray, or hair styling emulsion. The composition may be formulated as an ointment or lotion for topical use in areas with sparse hair. The invention also discloses a method of use of the composition, which is especially suited for treatment of the hair of infested children. The composition and method benefit from the soothing effects of aroma therapy. An additional benefit is that ecto-parasites do not develop resistance to the composition, which may be used repeatedly with no ill effects to the host.

Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among children.

Abstract: A multinutrient nutritional supplement is provided that is designed to be most effective in optimizing health, increasing the immunity and decreasing the instances and severity of infection particularly among adolescents.

Abstract: An antimicrobial and antiviral composition in powder form or in the form of a two part liquid concentrate for washing and sanitizing foods, food surfaces, food ware, process waters, animal quarters, and animal carcasses is described. The composition may also be used to reduce the microbial and viral population on animals; reducing human pathogenic microbes, reducing opportunistic pathogenic microbes on eggs, and treating skin diseases. The composition includes three reactive species which in solution form an oxidizing species, and optionally a food grade acid source. The reactive species include a natural source of a quaternary or protonizable nitrogen compound which is acceptable on foods, an oxidant and a halide source.

Abstract: The present invention describes a novel composition for the treatment of migraine, a common neurovascular syndrome, which can be elicited by functional and/or structural (symptomatic) disorders. This composition comprises taurine, coenzyme Q10 and additionally creatine, L-carnitine, certain vitamins and minerals, carbohydrates, proteins, fats and herbal extracts. Furthermore, the invention describes a method for the treatment of migraine.

Abstract: A formulation comprising lactoperoxidase, thiocyanate and/or iodide and a hydrogen peroxide donor system, in particular glucose oxidase and glucose, is useful for controlling plant-pathogenic microorganisms such as fungi and bacteria. Preferably the formulation also contains an oil.

Abstract: This invention relates to the method of non-invasively fortifying eggs with iodine as a dietary supplement without compromising the structural integrity of the egg. The eggs are placed in a solution comprising iodide or iodate salts of alkali or alkali earth metals at an effective concentration for a duration of between a few seconds to a few days. Iodine then passes through the egg shell to the interior of the egg until an adequate internal iodine concentration of iodide or iodate salts is produced.

Abstract: Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.

Abstract: An enzymatic antimicrobial composition comprising a haloperoxidase, a hydrogen peroxide source, a halide source, and an ammonium source, in particular an ammonium salt or an aminoalcohol, in which there is a hitherto unknown synergistic effect between the halide and the ammonium source.

Abstract: A stabilized solid oral pharmaceutical composition comprised of iodide and iodate as the active agents in the presence of one or more pharmaceutical excipients and a method for preparing these stabilized compositions.

Abstract: Compositions for the treatment and prevention of migraine or stress headaches wherein there is supplied a combination of potassium, magnesium and pyridoxine optionally in association with other nutrients and/or simple analgesics.

Abstract: Stable aqueous glycerin iodine concentrates are provided which are adapted for dilution in water to yield germicidal iodine use solutions. The concentrates include from about glycerin, iodine, and iodide ion. Preferably, the concentrates further include one or more additives such as compatible wetting agents, hydrotropes, thickening agents, additional emollients and buffering systems. The quantities of iodide ion and iodine are such that the ratio of iodide ion to iodine is from about 0.5:1 to about 6:1. The concentrates are stable for a period of at least about 3 months at room temperature and are dilutable at a ratio of 1 part concentrate with from about 2-80 parts water. The concentrates can be formulated to give very low free iodine values as concentrates which dramatically increase in diluted use solutions to values which are from about 2 to about 300 times greater than the free iodine in the concentrates.

Abstract: A composition for use in the rehydration and treatment of scours in calves. The composition includes fiber, electrolytes and three energy sources. The energy sources are sugar, medium chain triglycerides and glycine, present in a combined amount of about 14 percent by weight.

Abstract: A method for forming an iodine disinfecting solution that continuously generates free molecular iodine at a controlled average rate of at least 0.2 ppm per hour over a sustained and extended time period. The method involves combining persulfate anions and iodide anions in sufficient quantity in an aqueous medium having a resulting pH of less than about 6.5 so as to create an iodine generating capacity in said aqueous medium of between 1.5 and 6.5 with a generated concentration of at least 5 ppm of free molecular iodine and maintaining this concentration over the course of the extended time period.

Abstract: A composition is disclosed which is useful in alleviating, at least in part, symptoms of acne vulgaris, psoriasis or seborrhea, which includes a potassium-based compound a dermatologically acceptable base for the potassium-based compound, which is preferably a potassium salt, and which include potassium acetate, potassium aluminate, potassium arsenite solution, potassium bicarbonate, potassium bisulfate potassium bitartararte, potassium bromide, potassium carbonate, potassium chloride, potassium citrate, potassium gluconate, potassium glycerophosphate, potasium iodate, potassium iodide, potassium manganate, potassium permanganate, potassium phosphate monobasic potassium phosphate dibasic, potassium phosphate tribasic, potassium phosphite or a combination thereof. The composition is topically applied to the areas of a patient's skin which are afflicted with any of acne vulgaris, psoriasis or seborrhea.

Abstract: Stable, aqueous, iodine-based germicidal compositions are provided which include respective amounts of available iodine, non-ionic surfactant (e.g., polyoxyethylene, polyoxypropylene block copolymers) and an iodine-solubilizing halide ion selected from the group consisting of Cl.sup.- and Br.sup.- and mixtures thereof. Use of Cl.sup.- and/or B.sup.- substantially reduces or completely eliminates the need for iodide ion in the compositions for maintaining available iodine in solution. The compositions can be in the form of dilutable concentrates or final use solutions.

Abstract: Stable aqueous glycerin iodine concentrates are provided which are adapted for dilution in water to yield germicidal iodine use solutions. The concentrates include from about 30-87% by weight glycerin, from about 0.15-15% by weight iodine, from about 0.15-15% by weight iodide ion, and one or more additives such as compatible wetting agents, hydrotropes, thickening agents, additional emollients and buffering systems. The concentrates are stable for a period of at least about 3 months at room temperature and are dilutable at a ratio of 1 part concentrate with from about 2-80 parts water. The concentrates can be formulated to give very low free iodine values as concentrates, but provide dramatically increased free iodine values as diluted use solutions.

Abstract: A wound-healing preparation comprises a solution or paste of a non-reducing sugar and iodine in a vehicle consisting essentially of a pharamcologically acceptable glycol, especially glycerol, and, optionally, water. Preferably, the sugar is sucrose, especially that obtained from sugar beet, and the vehicle is substantially anhydrous glycerol. In one preferred embodiment, the preparation is in the form of a veterinary infusible solution and is particularly useful in the treatment of mastitis. In another embodiment, surgical sutures are treated by coating with the preparation to prevent the presence or abscesses around surgical suture lines.

Abstract: A teat-treating composition comprising a biocide in an aqueous medium characterised in that it also comprises a pseudo-plastically- or thixotropically-effective amount of Rhamsan gum is disclosed, as is the production thereof by mixing the components.Such compositions may be used to counter mastitis, particularly in dairy cattle, by dipping or spraying cows' teats.

Abstract: A method of making poultice by mixing together water, fine mineral powder, vinegar, herbal liniment solution, and hydrated magnesium sulfate (also known as Epsom salt) to produce a poultice capable of being applied to muscles, joints, or both which may be sore, injured, or both.

Abstract: Inter alia, an iodophor preparation composition comprising, in addition to a carrier, an iodide source, an oxidant and an acid source, characterised in that at least one of the iodide source, the oxidant and the acid source is only available for reaction with the other components when dissolved in an aqueous medium at the point-of-use is disclosed.

Abstract: Use of potassium iodide, administered orally, in an average daily dosage of 0.10 to 0.40 milligrams for the treatment of symptomatic Benign Prostatic Hyperplasia. The potassium iodide preferably is used in the form of a saturated aqueous solution of potassium iodide.

Abstract: The invention relates to a treatment for equine viral infections which includes potassium iodide, ammonium chloride and caffeine. A method of treating equine viral infections is also provided which involves administering the composition daily.

Abstract: A disinfectant composition comprising an aqueous solution or an alcoholic aqueous solution in a concentration of 83 v/v % or less which contains hydroxypropyl cellulose in a concentration of from 0.5 to 10 w/v %, iodine in a concentration of from 0.01 to 1.0 w/v %, and an iodide in a concentration of not more than 0.5 w/v %. The composition has reduced skin irritation while exhibiting sufficient bactericidal and viricidal activity.

Abstract: Silicone dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are shaped from (A) a diorganopolysiloxane matrix resin; (B) a reinforcing amount of a filler material (B.sub.1) therefor and/or an organic peroxide (B.sub.2); and (C) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid or liquid state at ambient temperature.

Abstract: This invention relates to a disinfecting epidermal cleaner using peroxidase, peroxide and iodide. The active components are maintained inactive until admixed in a define proportion with water. The pH at which the peroxidase is stored is between 7.0 and 9.0 and the pH of the admixture of the active components is between 3.0 and 6.5.

Abstract: Silicone dosage forms adapted for the continuous and controlled release of iodine values, notably to domestic water supplies for the treatment of the various disease states attributed to iodine deficiency, are heat-shaped from (A) a thermoplastic silicone copolymer, and (B) a therapeutically effective amount of at least one water soluble, nontoxic, organic and/or inorganic iodine compound which is in solid state at ambient temperature.

Abstract: An emulsion containing a substantially water resistant film-forming copolymer phase and iodine is claimed. The polymer-in-water emulsion forms a film that is a substantially fluid resistant, low tack, flexible film which adheres to skin and releases iodine to skin. The addition of iodate to emulsions having such a film-forming copolymer phase and iodine further enhances stability of the emulsion.

Abstract: There is disclosed a composition useful for medicated treatment of hooves of live animals. The composition comprises a major portion of a carrier and hoof penetrant, a minor amount of a filler comprising chiefly polyolefin fibers, and an oil-in-water emulsifier to form a staple composition. The composition can include optional quantities of a medicinal compound. A specific example of the compound comprises approximately 12 weight percent of chopped fibers of a polyolefin such as polyethylene or polypropylene, about 69 percent of a carrier comprising pine tar, paraffin wax and coconut oil, and an oil-in-water emulsifier such as an aliphatic alcohol or alkyl glucose fatty acid ester. Preferably, the composition also includes a medicinal compound such as alcohol, iodine or a soluble iodide. The method comprises packing the hooves of live animals such as horses with the composition.

Abstract: Povidone-Iodine (PVP-I) solutions stable according to U.S.P. standards and a method for preparing the same are disclosed. The PVP-I solution includes a microbicidal effective amount of available iodine and an alkalinizing agent in an effective amount to maintain the stability of the solution for a desired shelf-life of the solution when said solution is stored in a substantially nonpermeable container, the solution being non-buffered. In preferred embodiments, the iodophor solution is a microbicidal PVP-I solution for ophthalmic use.

Abstract: A method is provided for strong base anion exchange resins containing high concentrations of pentaiodide (I.sub.5.sup.-). The resins are prepared from highly concentrated solutions of I.sub.5.sup.- and I.sub.3.sup.- ions. The exchanged ions, such as chloried (Cl.sup.-), are washed out of the resin after completion of the exchange reaction with the polyiodide ion mixture. The resulting product is a stable resin of predetermined I.sub.5.sup.- content, which is highly effective as a disinfectant for water, acting against water-borne bacteria, virus, and Giardia.

Abstract: An emulsion containing a substantially water resistant film-forming copolymer phase and iodine is claimed. The polymer-in-water emulsion forms a film that is a substantially fluid resistant, low tack, flexible film which adheres to skin and releases iodine to skin. The addition of iodate to emulsions having such a film-forming copolymer phase and iodine further enhances stability of the emulsion.

Abstract: According to the invention, a liquid deliquescent composition is substantially uniformly applied to grain, animal feed, animal feed ingredients, hay or poultry litter product, inhibiting moisture migration or translocation in the product and thereby inhibiting the formation of mold-generating accumulations of moisture adjacent the walls of storage containers for grain, animal feed, feed ingredients or hay which are subject to large overnight temperature drops, and similary inhibiting the formation of mold-generating accumulations of moisture adjacent the walls of grain elevators or silos subject to large seasonal temperature drops. Such inhibiting of moisture migration or translocation according to the invention also inhibits the formation of dry zones in grain, animal feed, feed ingredients, hay or poultry litter, thereby inhibiting the generation of dust from such products, including the inhibiting of dust generation during the screw-conveying of grain to storage.

Abstract: The method comprises forming a sporocide having a defined period of sporocidal activity comprising three components including a peroxide or peroxide generating material, a peroxidase and a salt of iodide which serves as a donor molecule; storing the three components in a nonreacting state to maintain the sporocide in an inactive state and admixing the three components in a aqueous based carrier to cause a catalyzed reaction by said peroxidase for generating free radicals and/or byproducts from the iodide salt (donor molecule) and contacting the surface or object to be sterilized with the activated mixture. The concentration level of the three components can be selected such that an active sporocidal state is maintained for any desired period of time.

Abstract: In the technology of applying, spraying, or sponging antimicrobially effective amounts of aqueous iodophor peroxide solutions to the udder surfaces of cows, or other animals to be milked prior to milking, the present invention comprises the improvement which avoids iodides and staining which consists essentially of the step of shampooing said udders with a non-staining shampoo containing (a) from about 0.5% to 2% of iodine in a povidone-iodine complex and (b) about 0.5% to 5% of hydrogen peroxide as a nascent oxygen source, said individual components (a) and (b) being combined, with water, at the time of use and having been maintained dry and out of contact with one another in a container or receptacle.

Abstract: A composition and method of producing same is disclosed herein which, when said composition is applied to human fingernails, will cause the fingernails of the user to become harder and stronger. The composition comprises potassium iodide placed into solution with other ingredients which may include ethyl alcohol and distilled water, with the resulting solution applied directly to fingernails as disclosed herein.

Abstract: A mold and dust inhibiting composition which has particular utility in connection with the storage and handling of animal feeds, grains, and hay, and also in connection with the use of animal litter such as poultry litter, as well as having general utility for controlling both mold and dust. The composition of the invention is an aqueous solution of one or more salts of propionic acid, one or more deliquescent substances, and also preferably one or more humectants. Propionate ions are made available for mold control by this solution just as effectively as propionic acid, but without the disadvantages of propionic acid including a bad odor, serious corrosive characteristics, and high volatility and hence short residual time. The deliquescent, and preferably also the humectant, prevent moisture from migrating toward container walls where there is a large day/night temperature differential, and also prevent dry regions from developing and producing potentially harmful dust.

Abstract: Halophors, e.g., bromophors, comprising a complex of sulfone, e.g., sulfolane, halide ion, e.g., sodium bromide, and halogen, e.g., bromine, are described. Solid, free-flowing halophor compositions of the aforesaid complex and an amorphous siliceous carrier are also described.

Abstract: This invention relates to a disinfecting epidermal cleaner using peroxidase, peroxide and iodide. The active components are maintained inactive until admixed in a .[.define.]. .Iadd.defined .Iaddend.proportion with water. The pH at which the peroxidase is stored is between 7.0 and 9.0 and the pH of the admixture of the active components is between 3.0 and 6.5.