Oxide Or Hydroxide Patents (Class 424/688)
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Patent number: 6475631Abstract: The present invention provides an antimicrobial agent consisting of glass which comprises 50 to 60 mole % of ZnO, 20 to 30 mole % of at least one member selected from the group consisting of B2O3 and P2O5, 1 to 10 mole % of at least one member selected from the group consisting of Al2O3 and ZrO2, 5 to 10 mole % of an alkali metal oxide and 0 to 15 mole % of SiO2 and an antimicrobial agent consisting of glass which comprises 50 to 70 mole % of ZnO, 20 to 35 mole % of P2O5, 0.5 to 10 mole % of Al2O3, 0.5 to 10 mole % of SnO2, 0 to 5 mole % of SiO2 and 5 to 10 mole % of an alkali metal oxide as well as an antimicrobial resin composition and antimicrobial artificial marble, each of which comprises a resin and the antimicrobial agent blended therewith. The antimicrobial resin composition and the antimicrobial artificial marble are excellent in their antimicrobial properties, resistance to color change and water resistance.Type: GrantFiled: July 14, 2000Date of Patent: November 5, 2002Assignee: Toagosei Co., Ltd.Inventors: Noriyuki Yamamoto, Koji Sugiura, Satoshi Yamato
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Patent number: 6465517Abstract: The present invention describes a novel composition for the treatment of migraine, a common neurovascular syndrome, which can be elicited by functional and/or structural (symptomatic) disorders. This composition comprises taurine, coenzyme Q10 and additionally creatine, L-carnitine, certain vitamins and minerals, carbohydrates, proteins, fats and herbal extracts. Furthermore, the invention describes a method for the treatment of migraine.Type: GrantFiled: July 11, 2000Date of Patent: October 15, 2002Assignee: N.V. NutriciaInventor: Luutsche Van Der Zee
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Publication number: 20020137749Abstract: The present disclosure relates to novel compositions which provide improved nutritional support for premenopausal and menopausal women and/or relief from symptoms associated with menopause, as well as prophylactic effects, and methods for using same.Type: ApplicationFiled: March 27, 2002Publication date: September 26, 2002Applicant: DrugTech CorporationInventors: R. Saul Levinson, Marc S. Hermelin, Mitchell I. Kirschner
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Patent number: 6451329Abstract: A pigmented emulsion cosmetic composition for reducing the shiny appearance of skin and cosmetically improving the appearance of skin imperfections comprising a cosmetically effective amount of mushroom extract and a method for reducing the shiny appearance of skin and cosmetically improving the appearance of skin imperfections comprising applying to the skin an emulsion cosmetic composition containing mushroom extract.Type: GrantFiled: March 16, 2001Date of Patent: September 17, 2002Assignee: Revlon Consumer Products CorporationInventors: Ida Marie Sandewicz, Tatyana Zamyatin, Julio Gans Russ
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Patent number: 6447809Abstract: A dietary supplement for benefitting human bone health includes a calcium source, a source of vitamin D activity, and an osteoblast stimulant. A preferred calcium source is microcrystalline hydroxyapatite, which also contains protein (mostly collagen), phosphorus, fat, and other minerals. A preferred source of vitamin D activity is cholecalciferol, and a preferred osteoblast stimulant is ipriflavone. In addition to these basic ingredients, the composition can further include various other minerals known to occur in bone, vitamin C, and glucosamine sulfate, all of which exert beneficial effects on growth and maintenance of healthy bone. A method for benefitting human bone health involves administering a daily regimen of the dietary supplement.Type: GrantFiled: May 11, 2000Date of Patent: September 10, 2002Assignee: Metagenics, Inc.Inventors: Kim C. Krumhar, Holly A. Johnson
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Patent number: 6423349Abstract: Compositions comprising glutamine in combination with other nutrients, including N-acetyl-cysteine and Vitamins A, C, E are disclosed. Such compositions can be administered for promoting recovery in patients undergoing elective surgery and for treating multiple organ system failure.Type: GrantFiled: August 24, 2000Date of Patent: July 23, 2002Assignee: Baxter International, Inc.Inventors: J. Dale Sherratt, Joann Somerville
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Patent number: 6423348Abstract: What is shown is an animal blood anticoagulant compound useful in the meat packing industry generally, and in slaughterhouse operations, particularly. The anticoagulant is effective when diluted with water at higher dilution ratios than earlier anticoagulants. In some field trials, this anticoagulant was at least as effective as previously known commercial anticoagulants when diluted by an additional 30%. The present anticoagulant preparation concentrate is an aqueous mixture of soft water (55.0%-65.0/%, w/w); tetrasodium ethylene diamine tetraacetate (Na4EDTA) (0.5%-3.0%, w/w); sodium hexametaphosphate (17.0%-24.0%, w/w); citric acid (5.0%-9.0%, w/w); and sodium hydroxide (4.0%-7.0%, w/w) to obtain a balanced pH that provides optimal chelating and anticoagulant activity. Optimal anticoagulant performance has been found to occur in the range of between pH 6.6 and pH 7.2.Type: GrantFiled: December 15, 1998Date of Patent: July 23, 2002Inventor: James C. Mickus
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Patent number: 6423343Abstract: This invention relates to a method for treating inflammatory symptoms such as burning, redness, itching, swelling and pain which accompany skin disorders other than wounds of the skin. The method comprising topical application of a topical medicinal composition comprising a non-interlinked, particulate bioactive glass mixed with a topical medicinal carrier to the site of the skin disorder.Type: GrantFiled: January 23, 1998Date of Patent: July 23, 2002Assignee: USBiomaterials CorporationInventors: Sean Lee, James L. Meyers
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Patent number: 6416790Abstract: The concentrate is a liquid mixture of about 1000 parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less than 0.10 microhmo to about 1.2 to 3 parts by volume of Willard Water as prepared in accordance with U.S. Pat. No. 3,893,943. The liquid concentrate is applied directly to a skin surface area having a burn or other dermal lesion to protect the area from bacterial contamination.Type: GrantFiled: March 13, 2000Date of Patent: July 9, 2002Assignee: Aqua Med, Inc.Inventor: John D. Young
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Patent number: 6407038Abstract: A method for controlling Tylenchid plant-parasitic nematodes through application of an effective amount of an alkaline-stabilized sludge is described. In accordance with particular embodiments, the alkaline-stabilized sludge may be applied to the plant, seed or locus thereof.Type: GrantFiled: June 16, 2000Date of Patent: June 18, 2002Assignee: Her Majesty the Queen in right of Canada, as represented by c/o Minister of Agriculture and Agri-Food CanadaInventors: Thomas William Welacky, Edward Topp
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Patent number: 6358537Abstract: A deodorant and antimicrobial dispersion is formed of a deodorant and antimicrobial component, a binder resin and an aqueous or oily liquid medium. The deodorant and antimicrobial component comprises an oxide or hydroxide of an alkaline earth metal, hydrated silica, and a cationic surfactant.Type: GrantFiled: May 3, 2000Date of Patent: March 19, 2002Assignee: Dainichiseika Color & Chemicals Mfg. Co, Ltd.Inventors: Akira Hoshino, Mikio Saji, Kozaburo Hayashi
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Patent number: 6355275Abstract: Described are methods of embolization using an embolizing agent composition that includes microparticles with carbon surfaces, and comprising a contrast agent. Preferred microparticles include a permanently radiopaque particle substrate and a pyrolytic carbon surface.Type: GrantFiled: June 23, 2000Date of Patent: March 12, 2002Assignee: Carbon Medical Technologies, Inc.Inventor: Dean A. Klein
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Patent number: 6322821Abstract: A composition for preventing and treating milk fever in freshening cows, and a method of administering the composition. The basic composition is a mixture of water, calcium chloride, propylene glycol, B vitamins and minerals. The calcium content is lower than conventional calcium treatments used for this purpose. The propylene glycol gives the cow an energy boost and sweetens the taste so the cow does not object to it as it does to conventional gels and liquids. The B vitamins stimulate the cow's appetite. The minerals replace minerals lost in the milk and also help the cow absorb calcium. The composition of the present invention is in a liquid form and is preferably administered using a 200-300 cc drench gun. The end of the dispensing tube of the drench gun is placed between the teeth and cheek of the cow near the receptors that stimulate the esophageal groove reflex.Type: GrantFiled: September 27, 1999Date of Patent: November 27, 2001Inventor: Jack W. Register
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Publication number: 20010038862Abstract: A method is provided for increasing the permeability of skin or mucosal tissue to a topically or transdermally administered pharmacologically or cosmeceutically active peptide, polypeptide or protein. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the peptide, polypeptide or protein through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. Formulations and drug delivery devices employing hydroxide-releasing agents as permeation enhancers are provided as well.Type: ApplicationFiled: December 14, 2000Publication date: November 8, 2001Inventors: Eric C. Luo, Tsung-Min Hsu
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Publication number: 20010038861Abstract: A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered nonsteroidal anti-inflammatory drugs (NSAIDs). The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the NSAID through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. Formulations and drug delivery systems for co-administering a hydroxide-releasing agent with an NSAID are provided as well.Type: ApplicationFiled: December 14, 2000Publication date: November 8, 2001Inventors: Tsung-Min Hsu, Eric C. Luo
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Publication number: 20010036483Abstract: A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered androgenic drugs. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the androgenic drug through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. Formulations and drug delivery systems for co-administering a hydroxide-releasing agent with an androgenic drug are provided as well.Type: ApplicationFiled: December 14, 2000Publication date: November 1, 2001Inventors: Eric C. Luo, Tsung-Min Hsu
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Transdermal administration of steroid drugs using hydroxide-releasing agents as permeation enhancers
Publication number: 20010033870Abstract: A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered steroid drugs. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the drug through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. Formulations and drug delivery systems for co-administering a hydroxide-releasing agent with a steroid drug are provided as well. Optimally, the steroid drugs are a combination of an estrogen and progestin that may be administered in female hormone replacement therapy, to provide female contraception, and the like.Type: ApplicationFiled: December 14, 2000Publication date: October 25, 2001Inventors: Eric C. Luo, Tsung-Min Hsu -
Patent number: 6287607Abstract: A composition useful as a dietary supplement for providing potassium, calcium, and citrate is presented, as well as processes for producing the composition, and methods for using the composition as a dietary supplement. Administration of the composition counters bone loss associated with aging or menopause by providing bioavailable calcium and, simultaneously, delivering alkali load. In addition, administration of the composition produces a substantial increase in urinary citrate, which counters kidney-stone formation.Type: GrantFiled: July 19, 1999Date of Patent: September 11, 2001Assignees: Mission Pharmacal Company, Board of Regents, University of Texas SystemInventors: Charles Y. C. Pak, George Alexandrides, Neill B. Walsdorf
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Patent number: 6254388Abstract: A method for whitening teeth which utilizes laser light to activate bleaching agents applied to the teeth. The mouth is first prepared so that the soft tissues of the gums are protected and only the teeth are exposed. The teeth are cleaned to remove any materials which will reduce or nullify the effects of the bleaching agents. A first bleaching composition comprising a peroxide compound is prepared and applied to the teeth. The teeth are exposed to laser light from an argon laser which light activates the peroxide to accelerate the bleaching process without heat. If further whitening is desired, a second bleaching composition comprising a peroxide compound is prepared and applied to the teeth. The teeth are briefly exposed to laser light from a carbon dioxide laser which heat activates the peroxide to accelerate the bleaching process.Type: GrantFiled: February 2, 1998Date of Patent: July 3, 2001Assignee: BriteSmile, Inc.Inventor: David K. Yarborough
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Patent number: 6248760Abstract: A tablet for the transmucosal administration of nicotine. The nicotine is in one or more layers upon a non-nicotine containing matrix. The nicotine layers rapidly dissolve in the mouth. The nicotine is then rapidly absorbed by the intra-oral mucosal surfaces. The short, rapid pulse of nicotine is similar to that given by cigarette smoking. The nicotine may be provided in a plurality of layers separated by one or more layers that are essentially free of nicotine to support the nicotine layers.Type: GrantFiled: April 14, 1999Date of Patent: June 19, 2001Inventor: Paul C Wilhelmsen
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Patent number: 6197815Abstract: Metal amino acid chelates for animals are beneficial for facilitating and promoting growth by increasing desired metallic ion uptake. The present invention is directed to a process for providing an animal fed additive by preparing metal amino acid chelates, and the metal amino acid chelate growth facilitator, promoter and enhancer prepared by the process.Type: GrantFiled: March 18, 1998Date of Patent: March 6, 2001Assignee: J.H. Biotech, Inc.Inventor: Hsinhung John Hsu
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Patent number: 6194007Abstract: Disclosed herein are compositions which are highly effective rodenticides. The compositions include a plurality of glass whiskers which rodents are naturally attracted to for purposes of nest building, or are otherwise induced to pick up in their mouths. Upon biting the whiskers for either transport or eating, the rodents oral mucosa becomes irritated, often to the extent that the rodents are unable to subsequently eat without excruciating pain. Hence, the rodents death by starvation is inevitable.Type: GrantFiled: December 19, 1998Date of Patent: February 27, 2001Inventor: Thomas Sharp
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Patent number: 6162469Abstract: A safe medical powder with excellent performances which is a magnetosensitive powder for diagnosis, therapy, or drug delivery and which, even when placed in the body for a prolonged period, neither suffers a decrease in magnetic sensitivity nor releases ions, etc. The medical powder comprises a base particle of a ferromagnetic metal having thereon a coating layer, wherein at least the outside of the coating layer comprises a bioinert substance. Preferably, the coating layer comprising a bioinert substance comprises a layer comprises a hydrolysate of an alkoxide compound.Type: GrantFiled: March 29, 1999Date of Patent: December 19, 2000Assignees: Nittetsu Mining Co., Ltd., Katsuta NakatsukaInventors: Takafumi Atarashi, Katsuto Nakatsuka
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Patent number: 6159505Abstract: Compositions for the treatment and prevention of migraine or stress headaches wherein there is supplied a combination of potassium, magnesium and pyridoxine optionally in association with other nutrients and/or simple analgesics.Type: GrantFiled: January 21, 1998Date of Patent: December 12, 2000Inventor: Edwina M. Piper
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Patent number: 6132701Abstract: A method for reducing oral malodor associated with halitosis includes containing the oral cavity of a person with an aqueous solution containing calcium hydroxide. The method includes the steps of mixing approximately one-half ounce of pure lime with every two gallons of water which causes an exothermic chemical reaction to form calcium hydroxide. The calcium hydroxide is slightly soluble in water and is thus allowed to settle to the bottom of the container, leaving an aqueous solution having a predetermined proportion of dissolved and suspended calcium hydroxide. This solution is withdrawn from the container for ingestion or for oral cavity rinse by a person.Type: GrantFiled: December 17, 1998Date of Patent: October 17, 2000Inventors: Narciso C. Perez, Virginia C. Perez
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Patent number: 6103274Abstract: A pharmaceutical, orally applicable composition is disclosed, whereby the composition contains at least one antacid active substance as well as more than 45% by weight of a sugar and/or sugar alcohol and between 12% and 35% by weight of water. The composition has a liquid or a semisolid consistency and is substantially free of preservatives.Type: GrantFiled: September 29, 1998Date of Patent: August 15, 2000Assignee: Rhone-Poulenc Rorer GmbHInventors: Winfred Jettka, Jorg-Christian Hager, Manfred Durr
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Patent number: 6086923Abstract: The present invention is directed to a method of inhibiting the growth of disease organisms on and in plants by directly applying an aqueous solution comprising urea and at least one water-soluble salt of a divalent cation and a monovalent anion to the seeds, stems, bark, leaves, seed heads or sub-surface root zones of said plants. The weight percent ratio of urea to divalent cation in these solutions should be from about 0.25-10.0 to 1.0. Preferred divalent cations include those of the alkaline earth metals and the transition metals. Most preferred are calcium, magnesium, zinc, manganese, copper, iron, cobalt, nickel and mixtures thereof. Preferred anions include nitrate, chloride, bromide and mixtures thereof. In more preferred solutions, the ratio of urea to divalent cation is from about 2.0-7.0 to 1.0. Particularly preferred solutions include calcium chloride as the water-soluble salt. Optionally, a second water-soluble salt of a divalent cation and a monovalent anion may be included.Type: GrantFiled: March 31, 1997Date of Patent: July 11, 2000Assignee: Stoller Enterprises, Inc.Inventor: Jerry Herman Stoller
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Patent number: 6066342Abstract: An antacid composition containing 20 to 75 weight percent calcium carbonate, 0.1 to 10 weight percent magnesium hydroxide, and 0.5 to 10 weight percent potassium hydroxide is disclosed. A method for neutralizing excess stomach acid by oral administration of the antacid composition of the invention is also disclosed.Type: GrantFiled: December 20, 1996Date of Patent: May 23, 2000Assignee: Tamer International, Ltd.Inventors: Ismail Macit Gurol, Kyle William Gano
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Patent number: 5958464Abstract: A composition for preventing and treating milk fever in freshening cows, and a method of administering the composition. The basic composition is a mixture of water, calcium chloride, propylene glycol, B vitamins and minerals. The calcium content is lower than conventional calcium treatments used for this purpose. The propylene glycol gives the cow an energy boost and sweetens the taste so the cow does not object to it as it does to conventional gels and liquids. The B vitamins stimulate the cow's appetite. The minerals replace minerals lost in the milk and also help the cow absorb calcium. The composition of the present invention is in a liquid form and is preferably administered using a 200-300 cc drench gun. The end of the dispensing tube of the drench gun is placed between the teeth and cheek of the cow near the receptors that stimulate the esophageal groove reflex.Type: GrantFiled: November 12, 1997Date of Patent: September 28, 1999Inventor: Jack W. Register
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Patent number: 5942255Abstract: The invention is directed to a method of enhancing lean tissue mass in a subject by administering calcium to the subject, thereby enhancing the lean tissue mass in the subject. The invention is also directed to a method of enhancing bone mineral content in a physically active subject comprising administering calcium to the subject, thereby enhancing the bone mineral content in the subject. The invention is also directed to a method of enhancing bone mineral content and of enhancing lean tissue mass in a subject comprising administering calcium to the subject, thereby enhancing the bone mineral content and enhancing the lean tissue mass in the subject. The invention is further directed to a milk-free composition for enhancing bone mineral content and/or for enhancing lean tissue mass in a physically active subject, comprising an effective amount of calcium.Type: GrantFiled: July 15, 1996Date of Patent: August 24, 1999Assignee: The University of MemphisInventor: Robert C. Klesges
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Patent number: 5935610Abstract: A pharmaceutical composition having buffering properties comprises as its primary ingredients calcium carbonate (CaCO.sub.3) and magnesium oxide (MgO; magnesia) that form the base for the compound. Potassium sorbate (CH.sub.3 CH: CHCH:CHCOOK) is provided as a preservative. Other ingredients include a tabletizing binder, vitamin complexes, minerals as antipathogens, and flavorings.Type: GrantFiled: March 5, 1996Date of Patent: August 10, 1999Inventor: Linsey McLean
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Patent number: 5914135Abstract: Calcium carbonate liquid antacid compositions containing one or more pH adjusting agents to maintain the pH above 9.0, preferably above 9.5. The resultant antacid liquid possesses superior resistance to microbial attack and enhanced taste properties.Type: GrantFiled: April 16, 1997Date of Patent: June 22, 1999Assignee: McNeil-PPC, Inc.Inventors: John J. Dubek, Gerard P. McNally, Bruce P. Smith
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Patent number: 5874065Abstract: The invention describes an oral anti-acid paste comprising anti-acid compound in a slow releasing carrier medium which disperses the anti-acid, and releases the anti-acid from the paste upon contact with the aqueous media such as saliva. The paste can be used by placement in the mouth for slow release of the anti-acid into the saliva thereby contacting the mucosa of the esophagus to inhibit irritation to the mucosa due to excess acid.Type: GrantFiled: June 26, 1997Date of Patent: February 23, 1999Inventor: Alan A. Pardini
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Patent number: 5858413Abstract: A pharmaceutical, oral composition of a liquid to semisolid consistency is disclosed, wherein the composition, substantially free of preservatives, contains at least one antacid active substance as well as more than 45% by weight, a sugar and/or sugar alcohol, relative to the ready-to-use composition, and up to 40% by weight, a pharmaceutically harmless solvent, relative to the ready-to-use composition.Type: GrantFiled: July 23, 1996Date of Patent: January 12, 1999Assignee: Rhone-Poulenc Rorer GmbHInventors: Winfred Jettka, Jorg-Christian Hager, Manfred Durr
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Patent number: 5830508Abstract: A calcium-based ophthalmic composition for treating dry eye is disclosed. The composition includes a hydrophobic carrier such as petrolatum and a calcium salt. The composition can further include a polyol such as glycerol, and an agent such as anhydrous lanolin, to enhance the interface between the carrier, and the calcium salt and polyol. Also disclosed is a method for treating dry eye comprising the step of administering the composition according to the present invention by placing the composition on the lateral portion of the lower eyelid margin. This method allows the composition to gradually disperse onto the cornea and conjunctiva.Type: GrantFiled: January 21, 1997Date of Patent: November 3, 1998Assignee: Deo CorporationInventor: Donald L. MacKeen
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Patent number: 5814346Abstract: The compound, in use, is sprinkled over the excrement for treatment to neutralize and eliminate the odour, spores, fungi, bacteria and microorganisms therein, and presents a first subcompound in powder comprising a mixture of diatoms (often referred to as infusorial earth), a calcium-based substance and a sulphur-based substance.Type: GrantFiled: June 6, 1996Date of Patent: September 29, 1998Assignee: Progetto Emme S.r.l.Inventor: Bruno Gamberini
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Patent number: 5814319Abstract: An anti-viral, anti-bacterial, and anti-cancer agent comprising as the effective component, an alkali extraction of Aspalathus linearis which is preferably obtained after extraction by hot water. The agent serves to treat and prevent bacterial infections; to treat and prevent cancer; and to treat or prevent viral infection, for example, infection caused by retroviruses, such as human T-cell leukemia and the AIDS virus. The agent has no side effects.Type: GrantFiled: March 22, 1996Date of Patent: September 29, 1998Assignee: Mitsui Norin Co., Ltd.Inventor: Masatoshi Nakano
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Patent number: 5786381Abstract: A cosmetic composition comprising a hydroxy material selected from a layered double hydroxides and hydroxy salts which is suitable for treating the skin and delivering thereto the benefit agents.Type: GrantFiled: May 13, 1997Date of Patent: July 28, 1998Assignee: Chesebrough-Pond's U.S.A. Co., Division of Conopco Inc.Inventors: Kevin Ronald Franklin, Susan Mary Houghton, Ian Gardner Lyle
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Patent number: 5776505Abstract: The invention relates to the combined use of ketoprofen and specific inorganic basic substances with an improved quality of action.Type: GrantFiled: August 30, 1996Date of Patent: July 7, 1998Assignee: Bayer AktiengesellschaftInventors: Joachim Maasz, Ingrid Hurner, Peter Kurka, Ralph Lange
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Patent number: 5776503Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.Type: GrantFiled: July 24, 1997Date of Patent: July 7, 1998Assignee: Baxter International Inc.Inventors: Leo Martis, Michael R. Jones
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Patent number: 5760094Abstract: Hydrolyzed gelatin has been found to provide an improvement in taste and mouthfeel when incorporated in small amounts into chewable tablets containing ingredients requiring taste masking. Medicinals and nutritional supplements may now be prepared as chewables for those who find tablets difficult to swallow, for example children and older adults, or for those who prefer the convenience. There is a particularly large improvement in the taste and mouthfeel of chewables incorporating magaldrate and/or calcium carbonate.Type: GrantFiled: May 6, 1997Date of Patent: June 2, 1998Assignee: Bayer CorporationInventors: Thomas A. Alexander, Lawrence J. Daher, Gerald Gold, Clarence L. Hancock, Donald L. Peterson
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Patent number: 5733272Abstract: The present invention comprises compositions and articles such as catamenials, diapers, pantiliners, adult incontinence garments, and underarm shields which minimize odor caused by body fluids and which provide a pleasant scent signal to indicate that the odor is being removed. This scent signal, provided by cyclodextrin/perfume inclusion complexes and/or matrix perfume microcapsules, assures the wearer that the product is working.Type: GrantFiled: June 6, 1995Date of Patent: March 31, 1998Assignee: The Procter & Gamble CompanyInventors: Gordon Francis Brunner, Toan Trinh, Thomas Alfred Inglin
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Patent number: 5716648Abstract: Compositions for use in the regulation of subnormal pH values in intestinal tract and for treatment of bowel diseases. The compositions comprise a coating and a substantially insoluble alkaline material confined within said coating, the composition being adapted so as to ensure the availability of an amount of said pH regulating alkaline material in the lumen of the gastrointestinal tract exhibiting subnormal pH values. E.g. In the proximal small intestine, the mid small intestine, the distal small intestine, the caecum, the ascending colon, the transverse colon, the descending colon, the sigmoid colon and/or the rectum. The compositions may also comprise a medicament for treatment of bowel disease, e.g. 5-aminosalicylic acid for the treatment of Crohn's disease and colitis ulcerosa. The administration may be oral composition or enemas or suppositories.Type: GrantFiled: December 21, 1995Date of Patent: February 10, 1998Assignee: Farmaceutisk Laboratorium Ferring A/SInventors: S.o slashed.ren Halskov, Svenn Kluver Jepsen
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Patent number: 5716649Abstract: A batch process for increasing the calcium content of a water solution comprises the placement of a tin catalyst, a glass fibrous material, and water into a sealed tank and the application of heat to the tank for predetermined time intervals at progressively decreasing temperatures. The resulting solution is then extracted from the tank, wherein the solution has between 200 ppm and 500 ppm concentration of calcium.Type: GrantFiled: March 20, 1997Date of Patent: February 10, 1998Inventor: Wal Hee Nam
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Patent number: 5713738Abstract: A method for whitening teeth which utilizes laser light to activate bleaching agents applied to the teeth is disclosed. The mouth is first prepared so that the soft tissues of the gums are protected and only the teeth are exposed. The teeth are cleaned to remove any materials which will reduce or nullify the effects of the bleaching agents. A first bleaching composition comprising a peroxide compound is prepared and applied to the teeth. The teeth are exposed to laser light from an argon laser which light activates the peroxide to accelerate the bleaching process without heat. If further whitening is desired, a second bleaching composition comprising a peroxide compound is prepared and applied to the teeth. The teeth are briefly exposed to laser light from a carbon dioxide laser which heat activates the peroxide to accelerate the bleaching process.Type: GrantFiled: September 5, 1996Date of Patent: February 3, 1998Assignee: BriteSmile, Inc.Inventor: David K. Yarborough
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Patent number: 5707646Abstract: A composition for oral preparations, having a complex formed by dispersing or dissolving an unpleasantly tasting basic drug and a functional polymer compound in a substance having a low melting point, 10 to 70% by weight, based on the composition, of sugar alcohol and 0.1 to 7% by weight, based on the composition, of basic oxide. The composition for oral preparation is excellent in masking unpleasantly tasting basic drugs and has excellent performance in biological use.Type: GrantFiled: September 9, 1994Date of Patent: January 13, 1998Assignee: Taisho Pharmaceutical Co., Ltd.Inventors: Toshio Yajima, Kuniaki Ishii, Nobuo Umeki, Shigeru Itai, Hidefumi Hayashi, Kimihide Shimano, Ikuo Koyama
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Patent number: 5698230Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.Type: GrantFiled: March 24, 1997Date of Patent: December 16, 1997Assignee: Baxter International Inc.Inventors: Leo Martis, Michael R. Jones
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Patent number: 5688492Abstract: An oral hygiene composition comprises an effective amount of an antimicrobial agent in the form of a particulate non-ion-exchanging support material combined with a metal source providing antimicrobial metal ions in use. Preferably the antimicrobial agent is particulate titanium dioxide coated with silver chloride.Type: GrantFiled: July 22, 1996Date of Patent: November 18, 1997Assignee: The Boots Company PLC,Inventors: Edward Galley, Michael David Cooper
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Patent number: 5676975Abstract: A method of producing a burn symptom relief composition and the burn relief composition is provided which includes the use of blending natural ingredients each to the other to produce the composition for relief of burn symptoms. The method of producing the burn relief composition includes initially separating eggs into egg yolks and egg albumen. The egg yolks are then incorporated into a mixed glyceride composition to form a first intermediate composition which is emulsified by the addition of an aqueous solution of calcium hydroxide. The egg albumen is then mixed with the first intermediate composition to form a second intermediate composition which is further emulsified by the addition of still further additions of aqueous solutions of a calcium hydrate composition which is then stored and applicable for topical application to a mammalian body to relieve the symptoms of pain due to burn conditions.Type: GrantFiled: June 29, 1995Date of Patent: October 14, 1997Inventors: Alexander C. Dezes, George A. Dezes
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Patent number: 5665782Abstract: Hydrolyzed gelatin has been found to provide an improvement in taste and mouthfeel when incorporated in small amounts into chewable tablets containing ingredients requiring taste masking. Medicinals and nutritional supplements may now be prepared as chewables for those who find tablets difficult to swallow, for example children and older adults, or for those who prefer the convenience. There is a particularly large improvement in the taste and mouthfeel of chewables incorporating magaldrate and/or calcium carbonate.Type: GrantFiled: May 4, 1995Date of Patent: September 9, 1997Assignee: Miles Inc.Inventors: Thomas A. Alexander, Lawrence J. Daher, Gerald Gold, Clarence L. Hancock, Donald L. Peterson