Sulfate Patents (Class 424/709)
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Patent number: 9717805Abstract: The present invention relates to an image enhancing composition for the enhancement of contrast in a body cavity, wherein the viscosity of the composition is between 2000 and 4000 mPa·sec. It also relates to a method for enhancing contrast of an image of a body cavity, which method comprises introducing one single small amounts of an image enhancing composition into the body cavity. In another aspect, the present invention provides a high contrast image of a body cavity obtained by the method of the invention, in particular a 3-dimensional high contrast image.Type: GrantFiled: March 19, 2015Date of Patent: August 1, 2017Assignee: GynaecologIQ B.V.Inventors: Mark Hans Emanuel, Niek Exalto
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Publication number: 20150132351Abstract: Methods of using a polymeric composition are described for preventing or reducing the signs of aging. The polymeric composition can include a polymer matrix and one or a plurality of mineral filler(s), uniformly dispersed in the polymer matrix, having properties of absorption and/or emission in the far infrared region ranging from 2 ?m to 20 ?m.Type: ApplicationFiled: May 21, 2013Publication date: May 14, 2015Inventors: Thomas Gonzaga Canova, Gabriel Gorescu, Tarcis Cordeiro Bastos
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Publication number: 20150086650Abstract: There is described a method of treating a crop for the alleviation or prevention of a pest infestation, said method comprises the pre-harvest application to the crop of a composition comprising an acidulantType: ApplicationFiled: March 21, 2013Publication date: March 26, 2015Applicant: Natural Biotechnology SPRLInventor: Jeffrey Ian Dodd
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Publication number: 20150010653Abstract: An agricultural treatment method involves applying alkali metal bisulfate to modify surface pH on growing plants, or on seeds before planting, in an agricultural area. In certain aspects, the method involves applying an aqueous composition including the alkali metal bisulfate to the plants or seeds. The alkali metal bisulfate may be sodium bisulfate. An aqueous composition includes an alkali metal bisulfate in an amount from 0.1% to 5% by weight. The composition also includes a second material selected from stickers, antimicrobial agents, chelating agents, surfactants, or combinations thereof. Water makes up the final composition.Type: ApplicationFiled: July 2, 2013Publication date: January 8, 2015Inventors: Carl J. Knueven, Richard M. Basel
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Publication number: 20140335205Abstract: The subject invention pertains to materials and methods for the prevention and treatment of disease conditions associated with oxidative stress or a compromised reducing environment, including inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. Therapeutic compositions of the invention include compositions that can neutralize hydrogen peroxide, such as reducing agents and oxidizing agents. In one embodiment, a therapeutic composition of the invention comprises a reducing agent such as sodium thiosulfate. Therapeutic compositions of the invention can optionally include compounds with antibacterial activity, compositions that inhibit bacterial adherence to cells and tissue, compositions that inhibits epithelial lipid peroxidation, compositions that add viscosity to a solution, compositions that inhibit most cells, and/or compositions that help to seal or repair tight junctions between cells of the colonic epithelium of the gastrointestinal tract.Type: ApplicationFiled: April 1, 2014Publication date: November 13, 2014Inventor: Jay Pravda
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Publication number: 20140308265Abstract: The claimed invention is directed to compositions and methods effective in preventing microbial contamination or reducing microbial count associated with a contaminated surface, comprising a biocidal system comprised of a primary biocide, a pH buffer agent, a surfactant, all in an aqueous based carrier, wherein the compositions may be considered environmentally friendly.Type: ApplicationFiled: November 6, 2012Publication date: October 16, 2014Inventors: Burt R. Sookram, John W. Veenstra
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Patent number: 8840931Abstract: The present invention provides a pharmaceutical composition for dehydrating, atrophying and eliminating pathological tissues comprising inorganic polymeric ferric salt and/or inorganic polymeric ferric salt composite as its active ingredients, in which the inorganic polymeric ferric salt is polyferric sulfate, and the inorganic polymeric ferric salt composite is selected from a group consisting of poly-silicate ferric salts, polyphosphate ferric salts and their analogue. A surprising medical effect can be reached by treating pathological tissues with the pharmaceutical composition of the present invention which will make the treated pathological tissues dehydrated, atrophied, and absorbed or sloughed off.Type: GrantFiled: October 14, 2011Date of Patent: September 23, 2014Inventors: Kuok Leong Tam, Io cheng Tam, Hio man Tam
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Publication number: 20140271915Abstract: Use of a derivative containing C—O—P bonds in a controlled release form to treat patients with kidney failure. Moreover, it comprises the use of said derivatives together with other active substances, which particularly may be selected from a list comprising a calcimirnetic, vitamin, phosphate binder, thiosulfate, bisphosphonate, pyrophosphate, citrate, diuretic, antihypertensive and anticholesteraemic agent.Type: ApplicationFiled: March 14, 2014Publication date: September 18, 2014Applicant: LABORATORIS SANIFIT, S.L.Inventors: Joan PERELLO BESTARD, Carolina SALCEDO ROCA, Miguel David FERRER REYNES, Bernat ISERN AMENGUAL, Pieter H. JOUBERT
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Patent number: 8834939Abstract: Aqueous compositions, methods of manufacturing such aqueous compositions, and methods of removing reducing and/or suppressing malodors using such aqueous compositions are described. These compositions utilize a combination of hydrogen peroxide, a source of copper II, nonionic surfactant and alcohol to provide a highly effective and stable malodor removing, reducing and/or suppressing composition. The compositions are particularly useful as aerosol compositions for effective malodor removal, reduction and/or suppression in particular malodors from open sites such as landfill and in closed domestic environments such as the home. Also described is a stabilized hydrogen peroxide solution, which is stable on the addition of copper (II) salts.Type: GrantFiled: February 13, 2010Date of Patent: September 16, 2014Assignee: Probe Industries LimitedInventor: Peter Carty
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Publication number: 20140248377Abstract: The invention relates to a multiple emulsion for the application of at least one pharmaceutical or cosmetic active ingredient which has an external water phase W1, an oil phase O dispersed in the external water phase W1 and an internal water phase W2 dispersed in the oil phase O, where, in the internal water phase W2, at least one electrolyte selected from the group of the alkali metal and alkaline earth metal halides and sulphates and at least one hydrophilic active ingredient is provided. In order to achieve a high stability of the emulsion, the invention envisages that the external water phase comprises a hydrophilic emulsifier which is a polymer of ethylene oxide and propylene oxide, and that the oil phase O is formed by triacylglycerides and has a lipophilic emulsifier from the group of dimethicones.Type: ApplicationFiled: August 2, 2012Publication date: September 4, 2014Applicant: STERNA BIOLOGICALS GMBH & CO. KG BIOMEDIZINISCHES FORSCHUNGSZENTRUMInventors: Frank Runkel, Thomas Schmidts
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Publication number: 20140242188Abstract: An aqueous composition with a higher-than-neutral pH includes a significant amount of one or more surfactants and large amounts of osmotically active solutes. This composition, as well as an acidic counterpart and solid materials, can be used in a variety of applications such as wound care, oral care, medical equipment reprocessing, healthcare acquired infection and implant treatment.Type: ApplicationFiled: October 8, 2012Publication date: August 28, 2014Applicant: Next Science, LLCInventor: Matthew Franco Myntti
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Publication number: 20140234225Abstract: The present invention is directed to nanoparticulate active agent compositions comprising lysozyme as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate active agent composition of the invention and methods of making and using such nanoparticulate and pharmaceutical compositions.Type: ApplicationFiled: February 17, 2014Publication date: August 21, 2014Applicant: Alkermes Pharma Ireland LimitedInventors: Christian F. Wertz, Niels P. Ryde
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Patent number: 8778306Abstract: The present invention provides compositions, systems, kits, and methods for preparation prior to a colonoscopy or other gastrointestinal procedure. In particular, the present invention provides a colon lavage system comprising an aqueous portion and a solid portion.Type: GrantFiled: April 20, 2010Date of Patent: July 15, 2014Inventor: Dale R. Bachwich
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Patent number: 8778405Abstract: An array of pharmaceutical formulations characterized by the presence of molecular oxygen comprising four elements which, in combination, furnish benefits for the health of patients with HIV AIDS: (i) weight increase of the patient; (ii) increase of appetite; (iii) reduction of diarrhea; (iv) reduction of the wasting syndrome; (v) increase of stability of mood; (vi) increase of muscular mass. (vii) decrease of opportunistic diseases, in particular infections caused by Candida, herpes virus, cytomegalovirus, Kaposi's sarcoma; (viii) prolongation of the period wherein the patient does not require to take antiretrovirals; (ix) increase of acceptance of pharmacological treatment; x. reduction of gastritis, nausea or vomiting, headache; (xi) reduction of cases with anemia or thrombocytopenia; and (xii) a change in the phase of the disease in the patient.Type: GrantFiled: May 10, 2011Date of Patent: July 15, 2014Assignee: Comercializadora S. Car. Borr S.A. de C.V.Inventor: David Izquierdo Alcalde
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Publication number: 20140193525Abstract: Methods for treating or preventing radiocontrast agent induced kidney injury in a mammal are disclosed, the methods comprising administering to the mammal a first effective amount of a chalcogenide composition prior to administering a radiocontrast agent to the mammal.Type: ApplicationFiled: August 15, 2013Publication date: July 10, 2014Applicant: Fred Hutchinson Cancer Research CenterInventors: Chienmin Su, Csaba Szabo
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Patent number: 8771723Abstract: The present invention concerns the reduction of gastro-intestinal methanogenesis in ruminants with the aid of agents that compete for the hydrogen atoms required by methanogens during normal fermentation of ingested feed. The invention in one aspect resides in the findings that both nitrate reductive pathways as well as sulphate reductive pathways outcompete gastro-intestinal methanogenesis in ruminants and, that the methanogenesis reducing effects of nitrate and sulphate are completely additive. At the same time the combined administration of nitrate and sulphate was found to be fully effective to avoid or mitigate the potential problems of nitrite intoxication normally encountered when using nitrate alone, which effect is further enhanced, where necessary, by the addition of a nitrite reducing probiotic micoroorganism.Type: GrantFiled: July 23, 2010Date of Patent: July 8, 2014Inventors: Hindrik Bene Perdok, Sander Martijn Van Zijderveld, John Richard Newbold, Rob Bernard Anton Hulshof, David Deswysen, Walter Jan Jozef Gerrits, Jan Dijkstra, Ronald Alfred Leng
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Publication number: 20140186470Abstract: The invention provides a colon cleansing solution comprising: a) 300 to 800 mmol per litre ascorbate anion provided by a mixture of: (i) ascorbic acid and (ii) one or more salts of ascorbic acid the components (i) and (ii) being present in a molar ratio of from 1:4.5 to 1:7.0; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods an kits associated with, or making use of the solutions, and compositions for the preparation of the solutions.Type: ApplicationFiled: March 10, 2014Publication date: July 3, 2014Inventors: Lucy Clayton, Alasdair Cockett, Mark Christodoulou, Ian Davidson, Lynn Farrag, Marc Halphen, Leighton Jones, Vanik Petrossian, Peter Stein, David Tisi, Alex Ungar, Jeffrey Worthington
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Publication number: 20140170245Abstract: Provided is an inorganic composite compound having reduced oxygen and a high reducing ability, which includes elements having a positive atomic valence of a plant-derived component and a sulfur compound. The compound provides a therapeutic treatment effect and a pharmacological effect and is useful to suppress the influence of active oxygen (oxidization) and cannot be produced by a synthetic chemical technique.Type: ApplicationFiled: June 29, 2012Publication date: June 19, 2014Inventors: Eiki Nakayama, Masahiro Sugawara
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Publication number: 20140134251Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.Type: ApplicationFiled: October 23, 2013Publication date: May 15, 2014Applicant: PULMATRIX, INC.Inventors: Michael M. LIPP, Robert W. CLARKE, David L. HAVA, Richard BATYCKY, John HANRAHAN
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Publication number: 20140106040Abstract: There is described a method for the decontamination of (whole) fruit and/or vegetables comprising: (i) an optional first step of pre-washing the fruit and/or vegetables in high concentration of the decontaminant to deal with heavy spoilage; (ii) washing the fruit and/or vegetables in a low concentration of the decontaminant to deal with any residual microbial presence; wherein the decontaminant comprises an acidulant, such as sodium hydrogen sulphate, citric acid, lactic acid and tannic acid.Type: ApplicationFiled: March 4, 2011Publication date: April 17, 2014Applicant: NATURAL BIOTECHNOLOGY SPRLInventor: Jeff Dodd
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Patent number: 8691285Abstract: Methods of using a non-irritant, low pH acidic composition to destroy undesirable microorganisms are described. The methods may be used on food products, food processing equipment, and in aqueous solutions.Type: GrantFiled: July 14, 2011Date of Patent: April 8, 2014Assignee: CMS Innovative Technologies, Inc.Inventors: Barry Cummins, David Creasey
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Publication number: 20140087007Abstract: Disclosed is a method for rapidly cleansing the intestines and colon of a patient by orally administering an aqueous hypertonic sulfate solution, and then an aqueous isotonic solution to induce purgation, the purgations induced resulting in intestinal and colonic cleansing in less than four hours from the administration of the sulfate solution.Type: ApplicationFiled: March 15, 2013Publication date: March 27, 2014Applicant: Braintree Laboratories, Inc.Inventors: Mark vB. Cleveland, Edmund V. Dennett, JR., John D. McGowan
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Patent number: 8663707Abstract: A method for treating atherosclerosis in a patient comprising maintaining an elevated level of alcohol in the patient's blood; and administering a calcium chelating agent is provided.Type: GrantFiled: July 24, 2012Date of Patent: March 4, 2014Inventor: Ajay J. Panchal
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Patent number: 8658193Abstract: Technologies are described herein for styptic compounds comprising a hemostatic or styptic agent suspended within a hydrophobic carrier medium. Example carrier mediums may include waxes, lipids, oils, or combinations thereof. The compound may be a semisolid at room temperature and soft enough to be easily dispensed and formed into or onto bleeding tissue of an animal or human. The hydrophobic qualities of the carrier medium can protect the styptic agent from absorbing moisture. The carrier medium can mechanically support positioning treatments adjacent to the bleeding tissue. The carrier medium can further serve to mechanically seal the tissue to aid in hemostasis while also protecting the tissue from debris and contamination. The carrier medium can aid in maintaining moisture within the tissue. Slurry-based manufacturing processes can support a substantially homogeneous dispersal of styptic agent throughout the carrier medium.Type: GrantFiled: June 8, 2012Date of Patent: February 25, 2014Inventor: Robert J. Greenwald
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Patent number: 8652464Abstract: The present invention is directed to nanoparticulate active agent compositions comprising lysozyme as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate active agent composition of the invention and methods of making and using such nanoparticulate and pharmaceutical compositions.Type: GrantFiled: December 4, 2012Date of Patent: February 18, 2014Assignee: Alkermes Pharma Ireland LimitedInventors: Christian F. Wertz, Niels P. Ryde
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Publication number: 20140030363Abstract: A method for treating atherosclerosis in a patient comprising maintaining an elevated level of alcohol in the patient's blood; and administering a calcium chelating agent is provided.Type: ApplicationFiled: July 24, 2012Publication date: January 30, 2014Inventor: Ajay J. Panchal
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Publication number: 20140010895Abstract: The invention provides a colon cleansing solution comprising: a) 300 to 2000 mmol per litre ascorbate anion provided by ascorbic acid, one or more salts of ascorbic acid, or a mixture thereof; and b) 10 to 200 g per litre polyethylene glycol. The invention also provides methods and kits associated with, or making use of the solutions. The invention also provides a method of cleansing the colon of a subject comprising: — administering to the subject an effective amount of a first cleansing solution; and then after a time interval-administering to the subject an effective amount of a second cleansing solution, where in the two cleansing solutions are as described in the specification.Type: ApplicationFiled: March 9, 2012Publication date: January 9, 2014Applicant: NORGINE BVInventors: Marc Halphen, Hans-Jurgen Gruss, Ian Cox, Alasdair Cockett, Peter Stein, Alex Ungar
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Publication number: 20130344210Abstract: A food treatment method involves applying alkali metal bisulfate to an outer surface of a food, by an application process beginning with the alkali metal bisulfate in a solution and ending with the alkali metal bisulfate at least partially crystallized when it contacts the food surface. In certain embodiments, the application process causes at least partial evaporation of solvent from the solution. For example, the application process may include forming droplets of the solution, and/or propelling the solution with a gas having a relative humidity not greater than 60% or a temperature of at least 20° C. In certain embodiments, the beginning solution is an aqueous solution including the alkali metal bisulfate at a concentration within a range from 30% to 80%.Type: ApplicationFiled: August 28, 2013Publication date: December 26, 2013Applicant: Jones-Hamilton Co.Inventor: Carl J. Knueven
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Publication number: 20130295200Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.Type: ApplicationFiled: April 5, 2013Publication date: November 7, 2013Inventor: Nuvo Research AG
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Patent number: 8568759Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.Type: GrantFiled: December 14, 2010Date of Patent: October 29, 2013Assignee: W. Neudorff GmbH KGInventor: Diana L. Parker
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Patent number: 8557299Abstract: An improved dietary and/or therapeutic supplement composition comprising a quantity of a dietary and/or therapeutic supplement agent having a pH that upon ingestion with food or a beverage would limit the effectiveness of the agent and a sufficient amount of an alkaline electrolyte additive is provided in combination with the agent to raise the pH of the composition to a level of from about 8 to about 12.5 to increase the effectiveness and functional utilization of the agent while the composition is in the person's stomach. In a preferred composition, the electrolyte additive is selected from the group consisting of calcium, magnesium and potassium electrolytes. The supplement composition may be in the form of tablet, capsule, powder or liquid forms. The supplement composition is designed to provide for optimum utilization of a dietary and/or therapeutic supplement agent when taken orally with food or a beverage.Type: GrantFiled: October 30, 2012Date of Patent: October 15, 2013Inventors: Janmarie Hornack, Lawrence E. Dorman
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Patent number: 8530560Abstract: Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described include a spacer for spinal fusion, craniomaxillofacial (CMF) structures, and other structures for tissue implants.Type: GrantFiled: January 30, 2009Date of Patent: September 10, 2013Assignee: DePuy Synthes Products, LLCInventors: Sean Hamilton Kerr, Ali Recber, Thomas Pepe, Dominique Messerli, Lawton Laurence, Ryan Walsh, Thomas Kueenzi, Brandon Randall
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Publication number: 20130224123Abstract: The present invention is directed to nanoparticulate active agent compositions comprising lysozyme as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate active agent composition of the invention and methods of making and using such nanoparticulate and pharmaceutical compositions.Type: ApplicationFiled: December 4, 2012Publication date: August 29, 2013Applicant: Alkermes Pharma Ireland LimitedInventor: Alkermes Pharma Ireland Limited
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Publication number: 20130189377Abstract: The present invention concerns solid compressed oral pharmaceutical compositions comprising a mixture of at least two sulphate salts selected from the group consisting of sodium, potassium and magnesium for use, in particular, in cleansing the colon or treating faecal impaction, constipation, faecal retention, intestinal gas and cramping, or flatulence in a mammal. Methods of producing such compositions are also disclosed.Type: ApplicationFiled: July 26, 2011Publication date: July 25, 2013Applicant: Norgine BVInventors: Alasdair Cockett, Paul Pay, Guy Cameron Nash
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Publication number: 20130136725Abstract: Alterations of redox homeostasis in mammals underlie a host of symptoms, syndromes and diseases, including AIDS and cancer, which can be successfully treated by administration to a mammal of therapeutically-effective amounts of sulfide compounds and/or thiosulfate compounds and/or thionite compounds and/or thionate compounds and/or any chemical species capable of providing to a subject in need thereof a sulfide compound, thiosulfate compound, thionite compound, or thionate compound. The unique compositions of this invention contain one or more “active sulfur substances” in combination with each other or with other therapeutic agents. The invention also encompasses the varying modes of administration of the therapeutic substances. In particular, a novel method of combining active ingredient with wet cellulose is provided, which allows the wet cellulose to function as an enteric carrier.Type: ApplicationFiled: January 28, 2013Publication date: May 30, 2013Applicant: Nuevas Alternativas Naturales Thermafat, S.A.P.I. de C.V.Inventor: Nuevas Alternativas Naturales Thermafat, S.A.P.I. de C.V.
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Patent number: 8399506Abstract: The present invention relates to the use of combinations of 4-bromo-2-(4-chloro-phenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and an oxidizing agent, for eradicating, eliminating or reducing aquatic organisms in ballast water or bilge water whereby 4-bromo-2-(4-chloro-phenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and the oxidizing agent are in respective proportions to provide a synergistic effect against fouling organisms. Suitable oxidizing agents are e.g.Type: GrantFiled: August 6, 2007Date of Patent: March 19, 2013Assignee: Janssen Pharmaceutica, NVInventor: Tony Mathilde Jozef Kempen
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Publication number: 20130017275Abstract: The present invention relates to herbal medicinal compositions and extracts thereof for inhibiting growth of cancer cells. One of the examples described in the present invention comprises Forsythiae fructus, Menthae Herba, Gardeniae Fructus, Scutellariae Radix, Lophatheri Folium, Glycyrrhizae Radix, Rhei Rhizoma, Na2SO4, and Atractylodis Rhizoma. The residual examples are described herein.Type: ApplicationFiled: September 13, 2012Publication date: January 17, 2013Inventor: Chen-Yu LEE
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Publication number: 20120294849Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.Type: ApplicationFiled: July 27, 2012Publication date: November 22, 2012Inventors: Mathias Brosz, FRIEDRICH WILHELM KUHNE, KLAUS BLASZKIEWITZ, THOMAS ISENSEE
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Patent number: 8303941Abstract: A composition comprising mineral water and a chelating agent present in an amount sufficient to maintain all of the minerals in the water in solution. The mineral water is preferably obtained from Mount Clemens, Mich., US, and is preferably chelated with an ammonium and/or a sodium salt of an acid selected from the group consisting of ethylenediaminetetraacetic acid, nitrilotetraacetic acid, ?-alaninediacetic acid, ethylenediaminosuccinic acid, aminotrimethylenephosphoric acid, serinediaacetic acid, asparaginediacetic acid, methylgylcinediacetic acid and mixtures thereof. The resultant chelated mineral water may be combined with a cosmetically acceptable skin-conditioning agent and a cosmetically acceptable topical carrier, thereby resulting in a cosmetic composition that will confer beneficial effects on the skin, e.g., softening, hydrating and healing effects.Type: GrantFiled: April 19, 2008Date of Patent: November 6, 2012Assignee: Geologix, Inc.Inventor: Stephen Musumeci
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Patent number: 8298588Abstract: An improved dietary and/or therapeutic supplement composition comprising a quantity of a dietary and/or therapeutic supplement agent having a pH that upon ingestion with food or a beverage would limit the effectiveness of the agent and a sufficient amount of an alkaline electrolyte additive is provided in combination with the agent to raise the pH of the composition to a level of from about 8 to about 12.5 to increase the effectiveness and functional utilization of the agent while the composition is in the person's stomach. The supplement composition is designed to provide for optimum utilization of a dietary and/or therapeutic supplement agent when taken orally with food or a beverage.Type: GrantFiled: April 11, 2008Date of Patent: October 30, 2012Inventors: Janmarie Hornack, Lawrence E. Dorman
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Publication number: 20120245074Abstract: The invention includes a GRAS preservative system including sodium bisulfate and a combination of specific organic acids that act in a synergistic capacity. The preservative further has the benefit of a higher melting point of approximately 110° or higher making it particularly suited for solid wash applications. According to the invention it has surprisingly been found that a combination of sodium bisulfate, sorbic acid, and benzoic acid produced better preservative properties than other organic acid combinations or each acid by itself.Type: ApplicationFiled: May 24, 2012Publication date: September 27, 2012Applicant: ECOLAB USA INC.Inventors: Janel Marie Kieffer, Victor Fuk-Pong Man
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Patent number: 8273384Abstract: The present invention provides novel methods of making a non-corrosive base solution for use as an alkalinity increasing agent and/or antioxidant. The present invention further provides novel compositions and methods which can be used to provide relief from disorders related to or complicated by acidosis or excessive free radical or other reactive oxygen species production including, but not limited to, gout, Lesch-Nyhan syndrome, hemochromatosis, Alzheimer's, amyotropic lateral sclerosis, arthritis, atherosclerosis, cancer, cataracts, chronic obstructive pulmonary disease, diabetes, cellulitis, coronary artery disease, heart failure, hypertension, inflammatory bowel disease, macular degeneration, multiple sclerosis, Parkinson's, Reynaud's phenomenon, reperfusion injury, pancreatic impairment, skin infections, Hepatitis C, methicillin-resistant Staphylococcus aureus and infection.Type: GrantFiled: July 2, 2008Date of Patent: September 25, 2012Inventor: Stephen Ray Wurzberger
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Publication number: 20120219527Abstract: The present invention concerns the reduction of gastro-intestinal methanogenesis in ruminants with the aid of agents that compete for the hydrogen atoms required by methanogens during normal fermentation of ingested feed. The invention in one aspect resides in the findings that both nitrate reductive pathways as well as sulphate reductive pathways outcompete gastro-intestinal methanogenesis in ruminants and, that the methanogenesis reducing effects of nitrate and sulphate are completely additive. At the same time the combined administration of nitrate and sulphate was found to be fully effective to avoid or mitigate the potential problems of nitrite intoxication normally encountered when using nitrate alone, which effect is further enhanced, where necessary, by the addition of a nitrite reducing probiotic micoroorganism.Type: ApplicationFiled: July 23, 2010Publication date: August 30, 2012Inventors: Hindrik Bene Perdok, Sander Martijn Van Zijderveld, John Richard Newbold, Rob Bernard Anton Hulshof, David Deswysen, Walter Jan Jozef Gerrits, Jan Dijkstra, Ronald Alfred Leng
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Publication number: 20120203356Abstract: Calcium sulfate composite particles for bone augmentation are disclosed. The composite particles are composed of aggregated calcium sulfate nanoparticles of a diameter from about 50 to about 800 nm, which include a mixture of calcium sulfate dihydrate and calcium sulfate hemihydrate. The composite particles have a diameter from about 200 to about 1,200 ?m, and a mean half-life no less than 18 days. Further disclosed is a bone grafting material for bone augmentation. The bone grafting material includes a mixture of the calcium sulfate composite particles and a second type of calcium sulfate particles having a particle diameter from about 2 to about 60 ?m, at a ratio from 1:1 to 4:1. The method of using the composite particles and the bone grafting material for bone augmentation is also disclosed.Type: ApplicationFiled: February 6, 2012Publication date: August 9, 2012Inventors: Sachin Mamidwar, Harold Alexander, John L. Ricci
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Publication number: 20120195979Abstract: The present invention is directed to a treatment composition for recreational water, comprising a high molecular weight water soluble resin composition made from long chain alkoxylated polymers or co-polymers that impart emollient properties to the recreational water, as well as articles of manufacture comprising packaging material and the treatment composition for recreational water contained within the packaging material. The present invention is also directed to methods for treating recreational water, and recreational water treated with the above treatment composition.Type: ApplicationFiled: April 13, 2012Publication date: August 2, 2012Applicant: ARCH CHEMICALS, INC.Inventors: Derek Francis PARISH, Christopher M. ZETENA
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Patent number: 8226986Abstract: The present invention provides novel stable, liquid compositions comprising chalcogenides or salts thereof. These compositions may be used for a variety of purposes, including the treatment and prevention of ischemic or hypoxic injury, as well as in the preservation of biological matter.Type: GrantFiled: March 16, 2011Date of Patent: July 24, 2012Assignee: Ikaria, Inc.Inventors: Kevin J. Tomaselli, Paul A. Hill, Thomas L. Deckwerth, Edward A. Wintner, Csaba Szabo
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Publication number: 20120107414Abstract: The present invention relates to pharmaceutical formulations for treating a respiratory tract infection or a pulmonary disease in an individual, comprising a calcium salt and a sodium salt, wherein the ratio of Ca+2 to Na+ is from about 4:1 (mole:mole) to about 16:1 (mole:mole). The invention also relates to methods of treating (including prophylactically treating) and reducing the spread of a respiratory tract infection, methods of treating (including prophylactically treating) a pulmonary disease or an acute exacerbation of a pulmonary disease, and methods of reducing the spread of an acute exacerbation of a pulmonary disease, comprising administering a pharmaceutical formulation that comprises a calcium salt and a sodium salt.Type: ApplicationFiled: March 26, 2010Publication date: May 3, 2012Applicant: Pulmatrix, Inc.Inventors: Michael M. Lipp, Robert W. Clarke, David L. Hava, Richard Batycky, John Hanrahan
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Publication number: 20120100119Abstract: Three types of trisiloxane surfactants having the basic formula: MDM? are described wherein the substituents on the differing M and M? groups, in conjunction with pendant polyalkylene oxide substituents on the D group render the surfactant resistant to hydrolysis under either basic or acidic conditions outside the pH range of 6.0 to 7.5. The compositions are useful in agricultural, household and cosmetic applications.Type: ApplicationFiled: December 8, 2011Publication date: April 26, 2012Applicant: Momentive Performance Materials Inc.Inventors: George A. Policello, Mark D. Leatherman, Wenqing Peng, Suresh K. Rajaraman, Sophia Xia
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Publication number: 20120052136Abstract: The present invention relates to isolated haemoglobin from worms belonging to the Nereididae family and its use in cell culture medium, in preservation solutions and as artificial oxygen carrier for transfusion.Type: ApplicationFiled: May 7, 2010Publication date: March 1, 2012Applicant: HEMARINAInventors: Morgane Rousselot, Delphine Dutheil, Franck Zal
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Publication number: 20120027869Abstract: Methods of using a non-irritant, low pH acidic composition to destroy undesirable microorganisms are described. The methods may be used on food products, food processing equipment, and in aqueous solutions.Type: ApplicationFiled: July 14, 2011Publication date: February 2, 2012Inventors: Barry Cummins, David Creasey