Carbonate Patents (Class 424/715)
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Publication number: 20100074973Abstract: The present invention relates to new thioxanthene modulators of dopamine D2 receptors, pharmaceutical compositions thereof, and methods of use thereof.Type: ApplicationFiled: August 21, 2009Publication date: March 25, 2010Applicant: AUSPEX PHARMACEUTICALS, INC.Inventors: Thomas G. Gant, Manouchehr M. Shahbaz, Sepehr Sarshar
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Publication number: 20100021545Abstract: Self-forming hybrid compositions consisting in admixed liquid and solid components enable the formation of bio-materials. The present invention proposes a) a thermo-sensitive self-forming liquid component, being water-based and containing at least a polycationic polymer such as chitosan, and an organic mono-phosphate source, which is a solution at a pH ranging from 6.5 to 7.4; b) a solid component being mineral and composed of at least one of calcium, fluoride, strontium, carbonate and phosphate salts. Solid mineral salts preferentially have a recognized bioactive potential such as the calcium phosphate salts for bones. Both solid and liquid components are admixed to form an injectable liquid slurry or pre-gelled paste that turn in situ into a hybrid uniform gel-like bio-material.Type: ApplicationFiled: October 8, 2009Publication date: January 28, 2010Applicant: BIOSYNTECH CANADA INC.Inventors: Cyril Chaput, Abdellatif Chenite
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Publication number: 20090324514Abstract: A composition and method are described for sanitizing or otherwise treating a material such as a non-living surface, living tissue, soil or atmosphere which may be contaminated by a toxin, chemical warfare agent, insect, prion, microorganism or other infectious agent. The composition generally includes an aqueous composition mixture that includes: (a) lower alkanol; (b) an alkalinating agent, and (c) a fatty acid salt and/or ester. The components are present in an effective amount to sanitize (or treat) a material (or modifying a chemical contained thereon) to which the composition is applied. Also described are methods of making the composition.Type: ApplicationFiled: April 28, 2009Publication date: December 31, 2009Applicant: UrthTech, LLCInventor: Aziz C. Awad
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Publication number: 20090311300Abstract: The invention relates to a stent with in particular a coated basic body made of an implant material the use of lithium salts as a coating material or a component of an implant material for stents and the use of lithium salts in a method for restenosis prevention. The inventive stent having a basic body made of an implant material is characterized in that (i) the basic body has a coating which comprises or consists of a lithium salt, and/or (ii) the implant material is biocorrodible and the basic body contains a lithium salt.Type: ApplicationFiled: June 2, 2009Publication date: December 17, 2009Inventor: Eric Wittchow
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Patent number: 7618656Abstract: A method for treating hyperphosphatemia using lanthanum carbonate, including analytically determining the amount of an impurity in the lanthanum carbonate sample is provided. This X-ray diffraction method preferably uses the Rietveld refinement.Type: GrantFiled: October 31, 2007Date of Patent: November 17, 2009Assignee: Shire International Licensing B.V.Inventors: Donald Hallenbeck, Simon Bates
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Publication number: 20090274775Abstract: The present invention relates to combinatorial therapies for treating anxiety, depression or psychotic conditions using a lithium salt and a psychoactive drug selected from the group consisting of serotonin reuptake inhibitor, a 5HT2 receptor antagonist, an anticonvulsant, a norepinephrine reuptake inhibitor, an ?-adrenoreceptor antagonist, an NK-3 antagonist, an NK-1 receptor antagonist, a PDE4 inhibitor, an Neuropeptide Y5 Receptor Antagonists, a D4 receptor antagonist, a 5HT1A receptor antagonist, a 5HT1D receptor antagonist, a CRF antagonist, a monoamine oxidase inhibitor, a sedative-hypnotic drug, and an atypical antipsychotic.Type: ApplicationFiled: December 2, 2008Publication date: November 5, 2009Inventor: Philip Maxwell Satow
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Publication number: 20090257968Abstract: The present invention provides an enhanced gelling agent composition comprising a mixture of an anionic surfactant and a coupling agent. The invention also describes compositions in gel form comprising: (a) a solvent selected from the group consisting of polar solvents, non-polar solvents and combinations thereof; and (b) a gelling agent in an amount sufficient to impart gelation to the composition, the gelling agent being a mixture comprising an anionic surfactant and a coupling agent. The gels of the invention may be substantially anhydrous or may optionally contain water as part of the formulation.Type: ApplicationFiled: May 6, 2009Publication date: October 15, 2009Inventors: Richard Walton, Edward T. Borish
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Publication number: 20090232895Abstract: The patent refers to a procedure and devices for the generation of dry aerosols, continuously, by mechanic self-erosion, by average stirring in air or air-oxygen feed, of some crystals with special structure obtained by controlled crystallization processes. There can be also used other salts known to have physiological effects or mixtures of saline crystals with capacities close to the micro-particle generation. The devices can be for human or veterinary individual use, in intensive therapies or for producing aerosols with therapeutic or preventive effect in public rooms.Type: ApplicationFiled: May 14, 2009Publication date: September 17, 2009Inventor: Costantin Pascu
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Publication number: 20090220621Abstract: A method for treating gastric acid disorders with a non-enteric coated proton pump inhibitor in a pharmaceutically acceptable carrier including a bicarbonate salt of a Group IA metal and a carbonate salt of a Group IA metal; and a pharmaceutical composition of a non-enteric coated proton pump inhibitor in a pharmaceutically acceptable carrier including a bicarbonate salt of a Group IA metal and a carbonate salt of a Group IA metal are disclosed. A presently preferred proton pump inhibitor is lansoprazole, a presently preferred bicarbonate salt is sodium bicarbonate, and a presently preferred carbonate salt is sodium carbonate. The composition is a fast-acting formulation which reduces the undesirable belching associated with proton pump inhibitor formulations that contain high doses of sodium bicarbonate.Type: ApplicationFiled: May 12, 2009Publication date: September 3, 2009Inventors: Rajneesh Taneja, Pramod Gupta
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Publication number: 20090214628Abstract: The present invention relates to compositions and their use for the treatment of human skin, particularly facial skin, to alleviate the symptoms of cosmetic or determatologic skin conditions. The invention relates to compositions for treating and ameliorating skin conditions including acne, rosacea and wrinkling caused by photodamage or conditions related to aging, hormonal imbalances, hyper-pigmentation, melasma, keratosis or the like. The invention can also be used to treat conditions of the scalp such as dandruff. The present invention also relates to compositions that can be used to remove biofilms from contact lenses. More particularly, this invention relates to a composition comprising (a) one or more metasilicate; (b) one or more carbonate; (c) one or more glyconate; and (d) one or more sulfate. The composition may also contain (e) salts, e.g., sea salts and other additives or active agents.Type: ApplicationFiled: August 4, 2006Publication date: August 27, 2009Inventor: Jan de Rijk
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Publication number: 20090175960Abstract: A first aqueous solution filled in an electrolytic cell (2) is electrolyzed by applying DC voltage between the electrodes 7a and 7b in said electrolytic cell 2, to form an oxidation field short of electrons in said aqueous solution; and then, a second aqueous solution with carboxylic acid dissolved in it is mixed into the first aqueous solution in oxidation field state, so that the first aqueous solution in oxidation field state obtains electrons and is deoxidized, and the carboxylic acid is oxidized, to produce carbonic acid gas in said aqueous solution. Therefore, the present invention can be used to produce carbonic acid gas solution at a low cost easily.Type: ApplicationFiled: September 22, 2006Publication date: July 9, 2009Applicant: OMSI CO., LTD.Inventors: Yoh Sano, Masahiko Asano, Hitoshi Yagi
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Publication number: 20090162448Abstract: Silver-containing particles, and methods of making silver-containing particles are disclosed.Type: ApplicationFiled: December 12, 2008Publication date: June 25, 2009Applicant: Nucryst Pharmaceuticals Corp.Inventors: Nicholas Dunwoody, Zachary S. Wilson
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Publication number: 20090155389Abstract: Disclosed herein are pharmaceutical compositions comprising an inverse serotonin receptor agonist or a serotonin receptor antagonist and an anti-psychotic agent. Disclosed herein are also methods of treating psychotic disorders using the disclosed pharmaceutical compositions.Type: ApplicationFiled: February 11, 2009Publication date: June 18, 2009Inventors: David M. Weiner, Robert E. Davis, Mark R. Brann
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Publication number: 20090022819Abstract: Dryness of keratin materials, in particular dryness of the skin, and especially disorders associated with dry and/or hyposeborrheic skin are treated by administering to individuals afflicted therewith, thus effective amounts of at least one extract of a non-photosynthetic and non-fruiting filamentous bacterium cultured in a medium which includes at least one non-sulfurous mineral and/or thermal water, e.g., an extract derived from the bacterium Vitreoscilla filiformis, in particular the strain ATCC 15551, cultured in a medium enriched with water from La Roche Posay.Type: ApplicationFiled: July 17, 2008Publication date: January 22, 2009Applicant: L'OREALInventors: AUDREY GUENICHE, LIONEL BRETON
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Patent number: 7476660Abstract: The present invention relates to a composition for organ preservation, comprising an inulin type fructan as an active ingredient. The composition for organ preservation can suppress the hypofunction of an organ and damage to a histological structure and can improve the state of preservation of the organ in the course of organ transplantation and the like.Type: GrantFiled: March 28, 2003Date of Patent: January 13, 2009Assignee: Meiji Seika Kaisha, Ltd.Inventors: Yoshihiko Masaki, Kazunari Yoshida, Tadao Endo, Hirofumi Nakamura, Yasuhito Tashiro
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Publication number: 20080317800Abstract: The present invention relates to a biocidal composition, a method for its production and the use of the biocidal composition.Type: ApplicationFiled: February 15, 2007Publication date: December 25, 2008Inventor: Djamschid Amirzadeh-Asl
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Publication number: 20080317855Abstract: An ingestible particulate composition comprises: a. an alginate and/or alginic acid; b. a bicarbonate and/or carbonate; c. an organic acid; and d. an agglomerant, being a compound, such as a low molecular weight polyol, which allows the particulate composition to flow yet which substantially does not release fine particulates into the air. Resulting particulate compositions have excellent flow characteristics, dust suppression, organoleptic properties and stability. They are highly suitable for administration direction into a patient's mouth, and ingested to alleviate oesophageal and gastric conditions.Type: ApplicationFiled: July 27, 2006Publication date: December 25, 2008Applicant: RECKITT BENCKISER HEALTCARE (UK) LIMITED,Inventors: Ian Gordon Jolliffe, Charles Trafford, Olav Gaserod
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Publication number: 20080317856Abstract: This invention relates to compositions with a capillary-active system with application-relevant differentiability and synergistic potential for use in mammals, especially humans. The invention accordingly relates to a composition that has a capillary-active system C optionally containing a capillary activator system CA consisting of drugs that increase blood flow, stabilize the vascular wall, and/or dilate the blood vessels; and/or a capillary-protective system CP comprising drugs for endothelial stabilization, lipoprotein protection, and for stabilization of leukocytes/platelets; and/or a capillary energy supply system CE comprising redox systems and cofactors in energy provision and energy carriers. This system C is combined with a selective action system S.Type: ApplicationFiled: July 26, 2005Publication date: December 25, 2008Inventors: Rolf D. Beutler, Karl-Heinz Schmidt, Bettina Funke, Kirstin Becker
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Patent number: 7465465Abstract: This invention relates to a chewable lanthanum formulation comprising a pharmaceutically effective amount of a lanthanum compound; and at least one chewable pharmaceutically acceptable excipient. This invention also relates to a pharmaceutical formulation in a tablet or in a powder comprising a pharmaceutically effective amount of a lanthanum compound produced by a process which comprises the steps of: a) powder blending the lanthanum compound and at least one pharmaceutically acceptable excipient in a mixer to form a mixture; or b) powder blending the lanthanum compound and excipients, compressing the resulting combination into a slug material or roller compacting the resulting combination into a strand material, and milling the prepared material into a free flowing mixture; and c) compressing the resulting mixture into a tablet or filing up the resulting mixture in a appropriate container.Type: GrantFiled: August 26, 2004Date of Patent: December 16, 2008Assignee: Shire Biochem Inc.Inventors: Robert Paul Haslam, Laura Anna Trespidi, Josephine Christine Ferdinando
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Publication number: 20080286220Abstract: The invention provides a hair treatment composition comprising i) a disaccharide; ii) a di-acid, and iii) a source of ammonium ions.Type: ApplicationFiled: March 23, 2005Publication date: November 20, 2008Inventors: Fraser Ian Bell, Stuart Keith Pratley, Richard Skinner
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Publication number: 20080286357Abstract: The present invention relates to a pharmacologic dosage unit which includes a multi-functional particulate system and a pharmacologically active agent. The multi-functional particulate system includes solid biologically-safe particles incorporated into a matrix and having a characteristic that each individual particle retains its original size. The invention also relates to methods of preparing, enhancing flow properties and compacting properties of a pharmacologic composition, increasing capacity for inclusion of ingredients, and increasing dispersion of actives. Finally, the invention includes a method for delivering an active agent to a patient.Type: ApplicationFiled: May 17, 2007Publication date: November 20, 2008Applicant: Balchem CorporationInventors: Bob Sherwood, Janos Szamosi, Paul Richardson
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Patent number: 7419680Abstract: Compositions useful in the prevention and treatment of osteoporosis and for bone and fracture repair. Slow-releasing calcium phosphate-based materials are disclosed, incorporating Mg, Zn, F and carbonate, which will promote bone formation and inhibit bone resorption and thus be agents for the cited uses.Type: GrantFiled: September 28, 2004Date of Patent: September 2, 2008Assignee: New York UniversityInventor: Racquel Z. LeGeros
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Publication number: 20080187603Abstract: The present invention describes a novel antimicrobial ion delivery system (IDS) article, methods of making the article, and its applications in cleaning dentures and dentistry equipment. The novel IDS entails a source of oligodynamic metal ions embedded in a matrix that allows for the release of metal ions in water at concentrations that are biocidals and prevent biofilm formation. The preferred IDS contains particles made of metallic alloys and bound to a matrix that ensures the controlled release of ions in water. The novel IDS is safe for use in humans and it is environment friendly and biodegradable.Type: ApplicationFiled: October 6, 2007Publication date: August 7, 2008Applicant: Quartek CorporationInventor: Reyad I. Sawafta
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Publication number: 20080175904Abstract: The present invention relates to a particulate material and a solid dosage form notably tablets comprising a regularly shaped calcium-containing compound such as a calcium salt as a therapeutically and/or prophylactically active substance and a pharmaceutically acceptable sugar alcohol such as, e.g., sorbitol and/or isomalt that has a micro structure as evidenced by SEM. The invention also relates to a process for the preparation of the particulate material and solid dosage form. The process involves agglomeration of the calcium-containing compound and the pharmaceutically acceptable sugar alcohol by means of roller compaction. The particulate material obtained by roller compaction is suitable for use in the further processing of the particulate material into e.g. tablets such as chewing tablets.Type: ApplicationFiled: May 24, 2005Publication date: July 24, 2008Applicant: Nycomed Pharma ASInventors: Jacob Mathiesen, Carsten M. Nielsen, Peder M. Olsen, Poul E. Bertelsen
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Publication number: 20080166431Abstract: A smooth, dry-feeling, less-greasy, substantially-odorless, ecotoxicologically-safe, wax-based composition with a melting point above 25° C., comprising one or more wax components selected from dialkyl carbonates, dialkylene carbonates, and mixtures of two or more thereof; less than 10%, by weight, of water; and (c) optionally, one or more components selected from the group consisting of one or more wax or oil components selected from the group consisting of dialkyl ethers, dialkylene ethers, dicarboxylic acids, hydroxyfatty alcohols, and mixtures of two or more thereof, as well as one or more wax-like lipid components, other than those in previously listed, one or more other oil components, liquid at 20° C. and immiscible with water at 25° C.Type: ApplicationFiled: March 19, 2008Publication date: July 10, 2008Inventors: Achim Ansmann, Ulrich Issberner, Stefan Bruening, Bettina Jackwerth, Daniele Hoffmann
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Patent number: 7381428Abstract: Stabilized lanthanum carbonate compositions containing a monosaccharide or disaccharide stabilizing agent are disclosed. Subjects having hyperphosphatemia can be treated by administering a pharmaceutical composition containing a therapeutically effective amount of the stabilized lanthanum carbonate formulation.Type: GrantFiled: November 9, 2005Date of Patent: June 3, 2008Assignee: Shire International Licensing B.V.Inventors: Josephine Christine Ferdinando, Peter Neil Davies
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Patent number: 7374776Abstract: The present invention relates to a composition for bone-filling, more particularly, to a bone-filling composition for stimulating bone-formation and bone consolidation comprising calcium sulfate and viscous biopolymers. The composition of the present invention can easily be administered into the missing part of injured bone. Since the composition of the present invention does not diffuse to surrounding organs, it can effectively be used for bone-filling material suitable for body.Type: GrantFiled: September 30, 2002Date of Patent: May 20, 2008Assignee: Regen Biotech, Inc.Inventors: In-San Kim, Byung Chae Cho
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Patent number: 7368121Abstract: A process for eradicating moss and liverwort which includes applying sodium percarbonate; and irrigating the moss. In some cases the process includes applying lime to control the pH of the moss and thereby constrain development of additional moss and said sodium percarbonate is a solid material.Type: GrantFiled: October 5, 2005Date of Patent: May 6, 2008Inventor: Robert A Larose
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Patent number: 7347994Abstract: The invention is a method for attracting mosquitoes by producing a volatilized acid by combining an acid precursor with water to produce the humidified vapor acid attractant, preferably hydrogen chloride. The humidified volatilized acid can be further combined with carbon dioxide, or carbon dioxide can be simultaneously produced to attract mosquitoes. The acid precursor can be a hydrate of ferric chloride, such as ferric chloride hexahydrate. The acid precursor can be impregnated in a carrier, and can be combined with water through exposure to water vapor in the atmosphere, the intentional addition of water, or water produced by a chemical reaction.Type: GrantFiled: September 12, 2003Date of Patent: March 25, 2008Assignee: ICA Trinova, LLCInventors: Joel Tenney, Tom Isaac, William Ernst
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Publication number: 20080038375Abstract: A bathing product for bathing comprises: a sodium hydrogen carbonate, commonly known as baking soda, being usable for softening the bathing water, removing body odor, revitalizing skin and facilitating enhanced body care or treatment, and a water sanitizing agent, being usable for effectively sanitizing the liquid and cleaning the bath apparatus without causing toxic effect to a bather for bathing in the liquid. The sodium hydrogen carbonate mixture may comprise 50-99% by weight sodium of hydrogen carbonate formed in powder form, and the water sanitizing agent may comprise about 1-10% by weight of trichloroisocyanuric acid.Type: ApplicationFiled: July 9, 2007Publication date: February 14, 2008Inventor: Soo Kyoung Park
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Patent number: 7323452Abstract: A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as catalysts or “pseudo” enzymes for the oxidation. These additives include multivalent transition metal ions, as well as complexes thereof, and NAD+ which enhance the oxidation reaction. The method described can act as a sobriety inducer and/or as an effective palliative for the unpleasant effects of overuse of ethanol.Type: GrantFiled: December 20, 2004Date of Patent: January 29, 2008Assignee: Wardan, L.L.C.Inventors: Ward B. Bowen, Jr., Daniel S. Daniel
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Patent number: 7312199Abstract: A process is provided for making (?)-epigallocatechin gallate (EGCG) by subjecting a green tea extract to chromatography on a macroporous polar resin, eluting EGCG from the resin with a polar elution solvent, optionally concentrating the eluate, optionally regenerating the resin by desorbing the remaining catechins, and optionally concentrating the desorbed catechins.Type: GrantFiled: November 9, 2005Date of Patent: December 25, 2007Assignee: DSM IP Assets B.V.Inventors: David Carl Burdick, Heinz Egger, Andrew George Gum, Ingo Koschinski, Elena Muelchi, Isabelle Prevot-Halter
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Patent number: 7306814Abstract: A composition is provided comprising a substance of interest encapsulated by a continuous layer of a plurality of salt crystals which layer is impermeable to the substance of interest. Also provided is a method of producing a continuous layer of a plurality of salt crystals, the salt comprising a cation and an anion, which method comprises (i) providing a substrate which comprises a plurality of negatively charged binding sites for the cation and/or a plurality of positively charged binding sites for the anion, and (ii) contacting the substrate with a solution of the salt under conditions which cause nucleation of salt crystals comprising the cation and the anion at a plurality of said binding sites, the plurality of charged binding sites being present on the surface of the substrate at a sufficient density so that the resulting plurality of salt crystals form a continuous layer.Type: GrantFiled: May 9, 2005Date of Patent: December 11, 2007Assignee: Conopco, Inc.Inventors: Michael Francis Butler, Mary Heppenstall-Butler, Christopher Rawlins
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Patent number: 7303755Abstract: The use of certain salts and aminoacids as stabilizer of the antibiotic Fosfomycin Tromethamol and pharmaceutical compositions containing them, is described.Type: GrantFiled: July 10, 2003Date of Patent: December 4, 2007Assignee: Zambon S.p.A.Inventors: Luca Rampoldi, Luca Pirrone, Sarah Faccin, Alessandro Grassano, Giovanni Gurrieri
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Patent number: 7270833Abstract: Use of potassium for the production of a cardioplegic solution for the prevention of stone heart development during acute cardiac ventricular fibrillation in connection with cardiopulmonary resuscitation is described, as well as a cardioplegic solution comprising potassium and a method for the prevention of stone heart developement during acute cardiac ventricular fibrillation in connection with cardiopulmonary resuscitation.Type: GrantFiled: August 7, 2001Date of Patent: September 18, 2007Assignee: Jolife ABInventor: Stig Steen
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Patent number: 7241460Abstract: The invention provides a method of treatment of a human or non-human subject to combat sub-dermal soft tissue pain therein, said method comprising administering to a subject in need thereof an effective amount of a physiologically tolerable strontium compound.Type: GrantFiled: September 27, 2002Date of Patent: July 10, 2007Assignee: Santosolve ASInventors: Egil Jellum, Bjørn Jarl Fagerlund, Clas Magne Kjølberg, Jo Klaveness
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Patent number: 7192609Abstract: Conditions such as kidney stones, which are characterized by undesired absorption of oxalate from the intestinal tract are conveniently treated using nontoxic salts of rare earth metal ions.Type: GrantFiled: April 22, 2002Date of Patent: March 20, 2007Assignee: Shire International Licensing B.V.Inventors: Michael J. Abrams, Gary J. Bridger, Simon P. Fricker, Stefan R. Idzan
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Patent number: 7153492Abstract: An effervescent solid composition of matter is provided, which comprises, as an active component, a substance selected from chitosan, its derivatives and salts thereof and a second component capable of releasing CO2 in an acidic environment. Also, methods for treatment of a mammal suffering from a dermal wound, or for prophylactic or wound-healing treatment of lactating animals prone to develop or suffering from mastitis, are provided. The methods comprise the steps of: a) admixing said effervescent solid composition of matter with an aqueous liquid to form a solution or suspension thereof; b) contacting said animals with said solution or suspension to provide such treatment.Type: GrantFiled: April 12, 2002Date of Patent: December 26, 2006Assignee: Medicarb ABInventors: Torbjörn Mathisen, Marcus Back, Åsa Hellman
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Patent number: 7078059Abstract: The invention provides a method for enhancing bone formation, inhibiting osteoclastic differentiation and/or activating osteoblastic differentiation whereby to manage, treat or achieve prophylaxis of bone disease which comprises administering to a human or animal subject suffering from, or susceptible to bone disease a therapeutically or prophylactically effective amount of a lanthanum compound.Type: GrantFiled: June 26, 2001Date of Patent: July 18, 2006Assignee: Shire Holdings AGInventors: Nigel D. Atherton, Joseph William Totten, Michael David Gaitonde
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Patent number: 7063865Abstract: A composition that will substantially reduce the deleterious effects of alcohol on the body and substantially reduce the side effects associated with hangovers (i.e. headaches, dizziness, nausea, dry mouth, etc) when taken as recommended. The composition includes an effective amount of (I)-glycine, (I)-glutathione, thiamine, magnesium, selenium, molybdenum. Other vitamins, mineral compounds, flavoring, coloring, and solubility agents may also be added.Type: GrantFiled: May 10, 2002Date of Patent: June 20, 2006Inventors: Jeremy Park Jones, Peter Kevin Dobler
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Patent number: 6994873Abstract: This invention refers to: multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional release granules, suitable for once-a-day administration also at high strengths of Lithium salts, and to the preparation process of said formulations.Type: GrantFiled: February 4, 2002Date of Patent: February 7, 2006Assignee: Valpharma S.A.Inventors: Roberto Valducci, Tiziano Alighieri, Serozh Avanessian
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Patent number: 6989159Abstract: Once daily pharmaceutical compositions containing lithium carbonate in the form of coated granules.Type: GrantFiled: August 6, 2001Date of Patent: January 24, 2006Assignee: JDS Pharmaceuticals, LLCInventor: Giulio Tarro
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Patent number: 6974590Abstract: A pharmaceutical dosage form adapted to supply a medicament to the oral cavity for buccal, sublingual or gingival absorption of the medicament which contains an orally administerable medicament in combination with an effervescent for use in promoting absorption of the medicament in the oral cavity. The use of an additional pH adjusting substance in combination with the effervescent for promoting the absorption drugs is also disclosed.Type: GrantFiled: February 20, 2002Date of Patent: December 13, 2005Assignee: Cima Labs Inc.Inventors: Sathasivan Indiran Pather, Rajendra K. Khankari, Jonathan D. Eichman, Joseph R. Robinson, John Hontz
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Patent number: 6899900Abstract: Disclosed are a multipurpose, high-functional, alkaline solution composition, preparation therefor and use thereof as a nonspecific immunostimulator. The composition comprises 1-25 parts by weight of borax (Na2B4O7.10H2O), 10?5-10?4 parts by weight of sodium thiosulfate (Na2S2O3.5H2O), 30-150 parts by weight of potassium carbonate, 30-200 parts by weight of refined sugar (C12H22O11), and 100-200 parts by weight of water, based on 100 parts by weight of sodium metasilicate (Na2SiO3.5H2O). In addition to bringing about an improvement in disease resistance, weight gain rate, crop yield, crop quality, harvest time, the composition shows nonspecific immunostimulating activities, including antibody production and immune enhancement, by activating immune cells, thereby maximizing vaccination effects on malignant viral diseases.Type: GrantFiled: April 25, 2003Date of Patent: May 31, 2005Assignee: BARODON-S.F. Corp.Inventors: Soo-Il Choi, Hyun-Suk Choi, Kyung-Soo Jeon, Byung-Woo Yoo, Yong-Ho Park
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Patent number: 6896908Abstract: This invention relates to a leach-resistant borate preservative for lignocellulosic-based products, providing resistance against insect and fungal attack for use in exterior and ground contact applications. The preservative compositions of this invention may be provided as a high strength liquid concentrate, suitable for transportation, storage and easy on-site dilution, or as a ready-to-use treatment solution. These wood preservative compositions include a borate preservative component and a co-biocidal metal fixative such as copper or zinc. The preservative compositions also contain volatile organic acid, free ammonia and ammonium salts to aid dissolution. Methods for the application of these preservative compositions to wood are also provided.Type: GrantFiled: November 14, 2001Date of Patent: May 24, 2005Assignee: U.S. Borax Inc.Inventors: Jeffrey D. Lloyd, Jennifer L. Fogel
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Patent number: 6884440Abstract: Disclosed are a multipurpose, high-functional, alkaline solution composition, preparation therefor and use thereof as a nonspecific immunostimulator. The composition comprises 1-25 parts by weight of borax (Na2B4O7.10H2O), 10?5-10?4 parts by weight of sodium thiosulfate (Na2S2O3.5H2O), 30-150 parts by weight of potassium carbonate, 30-200 parts by weight of refined sugar (C12H22O11), and 100-200 parts by weight of water, based on 100 parts by weight of sodium metasilicate (Na2SiO3.5H2O). In addition to bringing about an improvement in disease resistance, weight gain rate, crop yield, crop quality, harvest time, the composition shows nonspecific immunostimulating activities, including antibody production and immune enhancement, by activating immune cells, thereby maximizing vaccination effects on malignant viral diseases.Type: GrantFiled: April 25, 2003Date of Patent: April 26, 2005Assignee: Barodon-S.F. Corp.Inventors: Soo-Il Choi, Hyun-Suk Choi, Kyung-Soo Jeon, Byung-Woo Yoo, Yong-Ho Park
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Patent number: 6872408Abstract: The present invention provides a method for treating psychiatric disorders such as mania or depression in a patients, in particular, patients with a bipolar disorder, by providing substantially isotopically pure heavy water substantially free of protons, isotopically pure hydrogen-containing water substantially free of deuterium, isotopically pure carbonate compounds substantially free of deuterium, isotopically pure carbonate compounds substantially free of protons, isotopically pure phosphate compounds substantially free of deuterium, isotopically pure phosphate compounds substantially free of protons, or mixtures thereof to the patient. In particular, the present invention provides a method for treating manic symptoms in a patient and mania or depression in patients with a bipolar disorder.Type: GrantFiled: September 6, 2002Date of Patent: March 29, 2005Inventor: Rupert C. Bell
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Patent number: 6833362Abstract: A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or “pseudo” enzymes for the oxidation. Additives include the oxidant Nicotinamide Adenine Dinucleotide and a variety of other additives such as transition metal ions and complexes thereof which favor the oxidation reaction. The compositions described can act as a sobriety inducer and/or as an effective palliative for the unpleasant effects of overuse of ethanol.Type: GrantFiled: June 7, 2001Date of Patent: December 21, 2004Inventors: Ward Beryl Bowen, Jr., Daniel Salman Daniel
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Patent number: 6830764Abstract: Application of an alkaline earth metal salt selected from calcium and strontium salts can steadily denature the allergens those exist in the environment without any coloring trouble on the treated material.Type: GrantFiled: March 12, 2001Date of Patent: December 14, 2004Assignees: Shinto Fine Co., Ltd., Sumitomo Chemical Co., Ltd.Inventors: Keiichiro Inui, Mariko Mikame
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Publication number: 20040241252Abstract: The present invention pertains to a controlled release solid dose formulations of lithium carbonate, comprising lithium carbonate, optional pharmacologically acceptable excipients, lubricants including stearic acid, sodium stearyl fumerate, calcium stearate, and magnesium stearate, optionally glycine, and sodium carboxymethylcellulose. Tablet forms are compressed at various pressures. The sodium carboxymethylcellulose and optionally glycine increases the dissolution rate profiles for lithium carbonate formulations, particularly for those formulations stored for extended periods of time and at varying conditions of heat and humidity. A process of formulating such compositions, comprising the steps of mixing lithium carbonate with excipients, top spraying a solution of sodium carboxymethylcellulose and glycine onto the lithium mixture in a fluid bed granulator, milling, and pressing the resultant compound into tablets is also described.Type: ApplicationFiled: July 15, 2003Publication date: December 2, 2004Inventors: Christopher Charles Abney, Brandon Scott Hampton, James Russell Norton, Daniel Joseph Schave, George Ronald Tomaich