Lactobacillus, Pediococcus, Or Leuconostoc Patents (Class 435/252.9)
  • Patent number: 11963986
    Abstract: The application discloses Lactobacillus strains having a beneficial effect on the metabolic health on a mammalian subject. Further disclosed is compositions comprising such strains and the use thereof for improving the metabolic health or for lowering the blood glucose level in a mammalian subject.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: April 23, 2024
    Assignee: Novozymes A/S
    Inventors: Nanna Ny Kristensen, Alexandra Mattern, Delphine Marie Anne Saulnier, Jeffrey Schultchen, Teis Jensen, Benjamin Anderschou Holbech Jensen
  • Patent number: 11938156
    Abstract: An isolated and purified lactic acid bacteria is provided, which is Lactobacillus paracasei PS23 (PS23) and its applications in delaying aging process, improving immunomodulatory activity, reducing, preventing or treating allergic and inflammation, preventing or treating a chronic disorder and/or (vi) preventing and/or treating a mood disorder or a neurological condition.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: March 26, 2024
    Assignee: BENED BIOMEDICAL CO., LTD.
    Inventors: Ying-Chieh Tsai, Hui-Yu Huang, Chien-Chen Wu, Jyh-Shing Hsu
  • Patent number: 11911422
    Abstract: A Bifidobacterium lactis BL-99 strain capable of enhancing immunity and the use thereof, which belongs to the technical field of microorganisms, is described. The Bifidobacterium lactis BL-99 provided by the present invention is deposited in China General Microbiological Culture Collection Center CGMCC on Apr. 26, 2018 with the deposit number CGMCC No. 15650. The bacteria have gastric acid resistance and intestinal fluid resistance, can significantly promote the growth of Bifidobacterium and Lactobacillus, significantly increase antibody-producing cells and half hemolysis value HC50, activate NK cell activity, and can be used to prepare foods for immunity enhancement. It also has the effects in preventing osteoporosis, increasing blood calcium and/or phosphorus ions, which has a wide range of application prospects.
    Type: Grant
    Filed: March 3, 2022
    Date of Patent: February 27, 2024
    Assignee: Inner Mongolia Yili Industrial Group Co., Ltd.
    Inventors: Wei-Hsien Liu, Wei-Lian Hung, Ting Sun, Wen Zhao, Ignatius Man-Yau Szeto
  • Patent number: 11889835
    Abstract: The present invention relates to a plant growth regulator of elevating anti-stress ability and use thereof. The plant growth regulator, which is consisted of Lactobacillus fermenting culture solution, has excellent thermostability and safety without any side effect, significantly elevating ability against biotic and abiotic stresses. Therefore, the Lactobacillus fermenting culture solution can be applied as the plant growth regulator or a use in preparation of a composition for elevating anti-stress ability of a plant.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: February 6, 2024
    Assignee: GENMONT BIOTECH INCORPORATION
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Tsuei-Yin Huang, Hsiang-En Huang, Yu-Jen Hsu
  • Patent number: 11812770
    Abstract: The present application relates to a Lactobacillus paracasei or progeny thereof. Specifically, the present application relates to Lactobacillus paracasei 207-27 and a composition, culture, food product or dietary supplement containing the same. The present application also relates to the use of Lactobacillus paracasei 207-27 and the composition, culture, food product or dietary supplement containing the same in medicine.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: November 14, 2023
    Assignee: BYHEALTH CO., LTD.
    Inventors: Xuguang Zhang, Xiaolei Ze, Ruikun He, Fang He
  • Patent number: 11660312
    Abstract: The present invention relates to a Bifidobacterium bifidum inducing regulatory T cells (Treg), a polysaccharide derived from Bifidobacterium bifidum, and a probiotic strain producing a polysaccharide and, more particularly, a polysaccharide containing ?-1-6-glucan as an effective ingredient, a probiotic strain producing ?-1-6-glucan, a food comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a therapeutic agent comprising the polysaccharide or strain as an effective ingredient for alleviation of immune disease or inflammatory disease, a method for preparing induced regulatory T cells (iTreg) by treatment with the polysaccharide or strain, and a cell therapy product for prevention or treatment of immune disease or inflammatory disease, comprising the induced regulatory T cells prepared by the method.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: May 30, 2023
    Assignees: INSTITUTE FOR BASIC SCIENCE, POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Sin-Hyeog Im, Ravi Verma, Changhon Lee
  • Patent number: 11653689
    Abstract: The present invention relates to Bifidobacterium breve deposited as DSM 32356 and compositions comprising said strain. The composition may further comprise at least one other bacterial strain and/or at least one compound which may be an NSAID such as acetylsalicylic acid (aspirin). In a presently preferred embodiment the invention relates to Bifidobacterium breve deposited as DSM 32356 for use in the support of the defense against intestinal tissue damage such as intestinal mucosal breaks or lesions e.g. in connection with NSAID administration such as in connection with administration of acetylsalicylic acid (aspirin). The invention further provides a method of supporting the defense against intestinal tissue damage, the method comprising administering the Bifidobacterium breve strain deposited as DSM 32356 to a subject in need thereof, e.g. to a subject in need of NSAID treatment.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: May 23, 2023
    Assignee: Chr. Hansen A/S
    Inventors: Brynjulf Mortensen, Anders Damholt, Anja Wellejus, Vibeke Westphal Stennicke, Johan E. T. Van Hycklama Vlieg
  • Patent number: 11638431
    Abstract: An object of the present invention is to provide a fermented milk and polysaccharide capable of inhibiting cancerous cachexia. A fermented milk with cancerous cachexia inhibitory effect according to one aspect of the present invention contains Lactobacillus delbrueckii subsp. bulgaricus as an active ingredient. Also, polysaccharide with cancerous cachexia inhibitory effect according to another aspect of the present invention are produced from the Lactobacillus delbrueckii subsp. bulgaricus. It is preferable that the Lactobacillus delbrueckii subsp. bulgaricus is Lactobacillus delbrueckii subsp. bulgaricus OLL1073R-1 (accession number: FERM BP-10741).
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: May 2, 2023
    Assignee: MEIJI CO., LTD.
    Inventors: Hirotaka Kawanabe, Marie Nakamura
  • Patent number: 11590182
    Abstract: Disclosed herein are methods and compositions related to probiotic formulas. These formulas comprise the bacterial strain Lactobacillus crispatus WZ-12 or a derivative thereof. Other strains which can be included in the composition include, but are not limited to, Lactobacillus salivarius 1-14, or Lactobacillus reuteri 2-2, and derivatives thereof. These compositions can be used in a variety of methods to treat and/or ameliorate diseases, such as colonization of antibiotic-resistant bacteria in the host organism. Also disclosed herein are methods of treating those subjects in need thereof by administering the compositions disclosed herein.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: February 28, 2023
    Assignee: Ohio State Innovation Foundation
    Inventors: Hua Wang, Lu Zhang, Yang Zhou, Zihua Wang
  • Patent number: 11591416
    Abstract: The present invention refers to exopolysaccharide molecules, conditioned media or compositions comprising said molecules or media. Moreover, the present invention refers to use of said exopolysaccharide molecules, conditioned media or compositions as prebiotic, preferably to boost immune system.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: February 28, 2023
    Assignee: SOFAR S.P.A.
    Inventors: Andrea Biffi, Ruggero Rossi, Walter Fiore, Simone Domenico Guglielmetti, Silvia Balzaretti
  • Patent number: 11541085
    Abstract: Disclosed herein is a process for producing a postbiotic extract, which includes providing a first material having a first isoelectric point ranging from pH 1 to pH 6 and a second material having a second isoelectric point ranging from pH 4 to pH 8, admixing the first material and a probiotic microorganism with water having a pH greater than the second isoelectric point, so as to form a mixture, adding the second material into the mixture and then adjusting a pH of the second material-added mixture to between the first and second isoelectric points so that a precipitate is formed, and subjecting the precipitate to a cell wall isolation treatment to obtain the postbiotic extract. Use of the postbiotic extract is also disclosed.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: January 3, 2023
    Assignee: CHAMBIO CO., LTD.
    Inventors: Meei-Yn Lin, Hung-Pin Chiu, Yi-Heng Chiu
  • Patent number: 11517596
    Abstract: A method for alleviating arthritis includes administering to a subject in need thereof a postbiotic extract. The postbiotic extract is prepared by a process including the steps of providing a first material having a first isoelectric point ranging from pH 1 to pH 6 and a second material having a second isoelectric point ranging from pH 4 to pH 8, admixing the first material and a probiotic microorganism with water having a pH greater than the second isoelectric point, so as to forma mixture, adding the second material into the mixture and then adjusting a pH of the second material-added mixture to between the first and second isoelectric points so that a precipitate is formed, and subjecting the precipitate to a cell wall isolation treatment to obtain the postbiotic extract.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: December 6, 2022
    Assignee: CHAMBIOCO., LTD.
    Inventors: Meei-Yn Lin, Hung-Pin Chiu, Yi-Heng Chiu
  • Patent number: 11458175
    Abstract: The present disclosure relates to a composition comprising a Lactobacillus plantarum CJLP475 strain deposited under Accession No. KCCM12287P; and a Lactobacillus plantarum CJLP243 strain deposited under Accession No. KCCM11045P, and use thereof.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: October 4, 2022
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Hee-Yeon Kim, Ho Jin Moon, Kyu Yeol Son, Kyung Min Lee, Yoon Tack Jang, Sung Hun Kim, Gi Duk Bae, Bong Joon Kim
  • Patent number: 11390892
    Abstract: The present invention is in the field of a method of producing lactic acid in high yield in a sequencing batch reactor. Therein glucose may be used as feedstock for bacteria, which ferment the glucose into lactic acid. The reactor is operated under at least partly defined non-axenic conditions and in a cyclic mode.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: July 19, 2022
    Assignee: NATURE'S PRINCIPLES B.V.
    Inventors: Julius Laurens Rombouts, Marinus Cornelius Maria Van Loosdrecht, Robbert Kleerebezem, David Gregory Weissbrodt, Gerben Stouten, Maximilienne Toetie Allaart
  • Patent number: 11390692
    Abstract: Compositions are disclosed herein comprising dextran that comprises (i) 87-93 wt % glucose linked at positions 1 and 6; (ii) 0.1-1.2 wt % glucose linked at positions 1 and 3; (iii) 0.1-0.7 wt % glucose linked at positions 1 and 4; (iv) 7.7-8.6 wt % glucose linked at positions 1, 3 and 6; and (v) about 0.4-1.7 wt % glucose linked at (a) positions 1, 2 and 6, or (b) positions 1, 4 and 6. Aqueous forms of this composition have enhanced viscosity profiles. Further disclosed are methods of using compositions comprising dextran, such as increasing the viscosity of an aqueous composition. Enzymatic reactions for producing dextran are also disclosed.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: July 19, 2022
    Assignee: NUTRITION & BIOSCIENCES USA 4, INC.
    Inventors: Rakesh Nambiar, Rong Guan, Qiong Cheng, Robert Dicosimo, Jayme L. Paullin, Yuanfeng Liang, Charles R. Powley, Yefim Brun
  • Patent number: 11238261
    Abstract: An ultrasonic fingerprint recognition module is described that includes sensing units distributed in the form of array, where the sensing units include: a receiving electrode layer having a plurality of receiving electrodes distributed in the form of array; a piezoelectric material layer disposed on one side of the receiving electrode layer; an emission electrode layer disposed on a side of the piezoelectric material layer distal to the receiving electrode layer, and including a plurality of rows of emission electrodes; a selection circuit having an input terminal which is connected with an excitation signal and an output terminal which is connected with the emission electrode for selecting to transmit the excitation signal to the plurality of emission electrodes; and a pixel receiving circuit connected to the receiving electrode layer that receives a fingerprint signal.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: February 1, 2022
    Assignee: BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Xiufeng Li, Haisheng Wang, Xiaoliang Ding, Pengpeng Wang, Yuzhen Guo, Lijun Zhao, Chenyang Zhang, Yaqian Ji, Yanling Han, Peixiao Li
  • Patent number: 11207358
    Abstract: The present invention relates to a composition comprising a given Lactobacillus rhamnosus strain and a given Lactobacillus paracasei strain wherein the ratio of the given Lactobacillus rhamnosus strain to the given Lactobacillus paracasei strain (LR?:LP?) is higher or equal to 8:1 and to methods thereof.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: December 28, 2021
    Assignee: COMPAGNIE GERVAIS DANONE
    Inventors: Tamara Smokvina, Rebeca Martin Rosique, Philippe Langella
  • Patent number: 11166991
    Abstract: The invention relates to a novel bacterial strain deposited with the CNCM under number 1-4969. This strain has properties that are useful in the treatment of respiratory disorders. The invention also relates to compositions and uses of said strain.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: November 9, 2021
    Assignee: Institut National De La Recherche Agronomique
    Inventors: Muriel Thomas, Aude Remot-Brizion, Philippe Langella
  • Patent number: 11066694
    Abstract: The present invention concerns compositions and processes that use affinity tags for isolating, and detecting or quantifying analytes, including nucleic acids, proteins and polypeptides. Compositions include nucleic acid compositions and protein compositions with affinity binding pairs, including metal binding peptides and immobilized metals, or peptide affinity groups.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: July 20, 2021
    Assignee: Enzo Biochem, Inc.
    Inventors: Elazar Rabbani, Jannis G. Stavrianopoulos, James J. Donegan, Wayne Patton, Juan Carcamo
  • Patent number: 10835485
    Abstract: The present invention is concerned with microorganisms or fragments thereof as sensorically neutral oral care agents, particularly for prevention of dental calculus, as anti-caries agents and/or anti-oral malodor agents. The invention is furthermore concerned with compositions comprising microorganisms or fragments thereof for reducing mutans Streptococci. Such compositions can be used in oral care compositions, e.g. for caries prophylaxis, or for prophylaxis of dental calculus or oral malodor. They may also or instead be used for prevention or treatment of oral malodor. As the microorganisms and fragments thereof according to the present invention have a very low, unobtrusive smell and taste, they are particularly suited as sensorically neutral agents for preventment of dental calculus, caries, oral biofilm formation and/or for prevention or treatment of oral malodor.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: November 17, 2020
    Assignee: BASF SE
    Inventor: Markus Pompejus
  • Patent number: 10188684
    Abstract: The present invention provides a method for preventing or treating a functional gastrointestinal disorder in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier. The present invention further provides a method for preventing or treating visceral hypersensitivity in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier. Moreover, the present invention provides a method for preventing or treating functional abdominal pain, irritable bowel syndrome or constipation in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: January 29, 2019
    Assignee: National Yang-Ming University
    Inventors: Ying-Chieh Tsai, Jian-Fu Liao, Chih-Chieh Hsu
  • Patent number: 9854822
    Abstract: Microbial starter cultures. More specifically, a method for preparing a microbial starter culture wherein the microorganism is inoculated in a culture medium comprising at least one 5 yield enhancing agent selected from the group consisting of a purine base, a pyrimidine base, a nucleoside and a nucleotide. Such microbial starter cultures are useful in the manufacturing of food, feed and pharmaceutical products.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: January 2, 2018
    Assignee: CHR. HANSEN A/S
    Inventors: Børge Windel Kringelum, Niels Martin Sørensen, Christel Garrigues, Martin B. Pedersen, Susanne Grøn
  • Patent number: 9839656
    Abstract: A composition comprising specific Lactobacillus helveticus strains is provided for reducing the symptoms of allergies originating from food, respiratory or contact allergens. Preferably the composition reduces symptoms of allergies (secondary prevention) while also able to reduce sensitization (primary prevention).
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: December 12, 2017
    Assignee: Nestec S.A.
    Inventors: Sebastien Holvoet, Annick Mercenier, Marietta Weiss, Adrian Walter Zuercher
  • Patent number: 9771624
    Abstract: The multiple embodiments described herein comprise the genome of a probiotic Bifidobacterium longum bifidobacteria strain and genes encoded by the genome. Various novel Bifidobacterium longum are described.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: September 26, 2017
    Assignee: The Procter & Gamble Company
    Inventors: Douwe Van Sinderen, Jun Xu, Wenzhu (Steven) Zhao, Raymond A. Grant, Song Yuli, Charles Bascom, Duane Larry Charbonneau, Liam O'Mahony
  • Patent number: 9737577
    Abstract: An object of the present invention is to provide a useful composition that contains a highly safe lactic acid bacterium or a component derived from this lactic acid bacterium. The present invention relates to a composition comprising at least one lactic acid bacterium selected from the group consisting of Lactobacillus delbrueckii subsp. lactis strain KR-037 (NITE BP-395), Lactobacillus delbrueckii subsp. lactis strain KLAB-4 (NITE BP-394), and variants thereof, or comprising a component derived from the lactic acid bacterium. The composition of the present invention is useful as a preparation that has an excellent antiallergic function and also has at least one other function selected from an anti-autoimmune disease function, a diabetes-improving function, a neutral fat-lowering function, and so forth.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: August 22, 2017
    Assignee: KANEKA CORPORATION
    Inventors: Airo Tategaki, Toyoaki Watanabe, Kazuya Hamada
  • Patent number: 9629883
    Abstract: The present invention discloses different specific bacterial strains isolated from individuals without caries which are characterized in that they present inhibitory activity against cariogenic organisms. The invention also discloses a process for isolating said strains, as well as bioactive peptides, such as anti-microbial peptides of human and bacterial origin, which also show anti-cariogenic activity. Moreover, the present invention also discloses pharmaceutical and/or probiotic/prebiotic compositions, functional foods, mouthwashes, toothpaste, chewing gum, etc., that comprise at least one of the strains and/or at least one of the bioactive peptides described in the invention, or a combination thereof, which are useful in the treatment and/or prevention of infectious diseases of the buccal cavity, preferably caries.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: April 25, 2017
    Assignee: CENTRO SUPERIOR DE INVESTIGACIÓN EN SALUD PÚBLICA (CSISP)
    Inventor: Alejandro Mira Obrador
  • Patent number: 9185927
    Abstract: The present invention relates to a selected strain of Lactobacillus pentosus for use as a medication for the preventive or curative treatment of infections due to Gram-negative bacteria, preferably enterococci, coliforms and E. coli.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: November 17, 2015
    Assignee: Probiotical S.p.A.
    Inventors: Giovanni Mogna, Gian Paolo Strozzi, Luca Mogna
  • Patent number: 9169499
    Abstract: An engineering method was developed to allow genetic modification and isolation of lactic acid bacteria cells that lack lactate dehydrogenase and acetolactate decarboxylase activities. In cells with these modifications and an isobutanol biosynthetic pathway, improved production of isobutanol was observed.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: October 27, 2015
    Assignee: BUTAMAX ADVANCED BIOFUELS LLC
    Inventors: Brian James Paul, Wonchul Suh
  • Patent number: 9101158
    Abstract: The present invention addresses the problem of providing a soybean-derived raw material-containing food or beverage that improves problems with flavor and physical properties, such as the grassy smell caused by soybean raw materials, and markedly improves product quality, in a soybean-derived raw material-containing food or beverage using conventional soybean raw materials such soymilk or tofu. Provided are a milk-substitute composition, and an egg-yolk substitute composition, etc., characterized by including a soybean emulsion composition having a protein content relative to dry material of at least 25 wt %, a fat content (as a chloroform/methanol mixed solvent extract) relative to the protein content of at least 100 wt %, and an LCI value of at least 55%. Also provided are a variety of soybean-derived raw material-containing food and beverages using these compositions.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: August 11, 2015
    Assignee: FUJI OIL COMPANY LIMITED
    Inventors: Masahiko Samoto, Jiro Kanamori, Norifumi Adachi, Chizuru Ueno, Eriko Harada, Mai Kanda, Takahiro Tsuruda, Ayako Ogama, Yuki Usui, Koichi Saito, Kohsuke Ito, Hideo Sugano, Masashi Asanoma, Mitsutaka Kohno, Masayuki Shibata, Yuusuke Shishido, Sayuri Kitagawa, Miyuki Kanaya, Shigeru Ashida, Takayasu Motoyama
  • Patent number: 9101651
    Abstract: The present invention generally relates to the field of obesity. In particular the present invention relates to the use of probiotics to treat obesity. One embodiment of the present invention relates to the use of Lactobacillus rhamnosus CGMCC 1.3724 and/or Lactobacillus rhamnosus NCC 4007 for the preparation of a composition to support weight management, promote weight loss and/or to treat obesity.
    Type: Grant
    Filed: April 10, 2013
    Date of Patent: August 11, 2015
    Assignee: Nestec S.A.
    Inventors: Christian Darimont, David Philippe, Catherine Mace, Fabrizio Arigoni
  • Patent number: 9057112
    Abstract: The invention herein provides certain strains of lactic acid bacteria selected for their capability of promoting production of IL-10 and consequently proliferation of CD4+CD25+ TR cells, for prophylaxis and/or treatment of infant colic, a method of selecting such strains, and products containing such strains.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: June 16, 2015
    Assignee: BIOGAIA AB
    Inventors: Eamonn Connolly, Bo Mollstam
  • Patent number: 9040037
    Abstract: The present invention provides a triple vital bacteria composition, including: powder of Bifidobacterium longum, powder of Lactobacillus acidophilus, and powder of Streptococcus faecalis. The present invention further provides a method for preparing the above triple vital bacteria composition, as well as the protection agents, the fermenting culture medium and the seed culture medium used therein.
    Type: Grant
    Filed: February 3, 2008
    Date of Patent: May 26, 2015
    Assignee: Shanghai Sine Pharmaceutical Laboratories Co., Ltd.
    Inventors: Binhua Chen, Xuesong Wang, Liang Zhang
  • Publication number: 20150139968
    Abstract: The present invention relates to a composition used for treating picornavirus infection comprising at least one of the following bacterial strains: Lactobacillus paracasei GMNL-33 with the deposition numbers of CCTCC M 206133, Lactobacillus reuteri GMNL-89 with the deposition numbers of CCTCC M 207154 and Lactobacillus casei GMNL-277 with the deposition numbers of CCTCC M 2013197, and a pharmaceutically acceptable vehicle. The Lactobacillus casei GMNL-277 of the invention is a novel Lactobacillus isolated strain. In addition, the present invention also features the novel use of the composition of the Lactobacillus strains for treating picornavirus infection, and the mechanism of which is inhibition of virus infection by binding of the probiotic bacteria to viruses.
    Type: Application
    Filed: November 15, 2013
    Publication date: May 21, 2015
    Applicant: GENMONT BIOTECH INC.
    Inventors: Ya-Fang Wang, Jen-Ren Wang, Yi-Hsing Chen
  • Publication number: 20150132270
    Abstract: The present invention relates to novel strains of Lactobacillus as well as preparations and compositions, such as fermentation broths, protective cultures, final food or feed product with Lactobacillus alone or in combination with bacteria of the genus Propionibacterium. The present invention further relates to methods for the controlling of growth of a contaminant, such as a bacteria, yeast or mould by using these novel strains of Lactobacillus.
    Type: Application
    Filed: May 21, 2013
    Publication date: May 14, 2015
    Inventors: Connie Benfeldt, Heike Ursula Morgenstern
  • Patent number: 9011877
    Abstract: TRFs useful for identifying strains of interest are provided. A method of identifying one or more strain that can be used as a direct-fed microbial is also provided. One or more strain identified by the method is additionally provided. A method is also provided for administering to an animal an effective amount of the one or more strain. Additionally provided is an isolated strain chosen from at least one of Lactobacillus acidophilus strain P1B c6 (NRRL B-50103), Lactobacillus salivarius strain o246e 33w (NRRL B-50102), Pediococcus acidilactici strain o246e 42 (NRRL B-50171), and Pediococcus acidilactici strain P1J e3 (NRRL B-50101). An isolated strain having all of the identifying characteristics of one of the strains listed above is also provided. One or more strain can be administered as a direct-fed microbial to an animal. Methods of preparing a direct-fed microbial are also provided.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: April 21, 2015
    Assignee: Dupont Nutrition Biosciences APS
    Inventors: Mari Ellen Davis, Joshua M. Rehberger, Charles Maxwell, Thomas G. Rehberger, Mike King
  • Patent number: 9011838
    Abstract: Methods and compositions are hereby disclosed for reducing the numbers of E. coli O157:H7, Salmonella or other pathogens in an animal. The methods include administering to the animal a lactic acid producing bacterium at a relatively low dosage in combination with a lactate utilizing bacterium, followed by administration of the lactic acid producing bacterium at a relatively high dosage. The disclosed methods help achieve pre-harvest food safety and enhance feed performance while keeping the total cost relatively low. The preferred lactic acid producing bacterium is Lactobacillus acidophilus/animalis and the preferred lactate utilizing bacterium is Propionibacterium freudenreichii.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: April 21, 2015
    Assignee: Nutrition Physiology Company, LLC
    Inventors: Douglas Ware, Peter Anderson
  • Patent number: 8986675
    Abstract: The present invention relates to the prevention and treatment of obesity and obesity related metabolic syndrome, particularly to the prevention and treatment of obesity by changing intestinal flora. The characteristics of intestinal bacteria are transformed by administration of a microorganism preparation which improves free fatty acid absorption by the bacteria, and free fatty acid absorption in the gastrointestinal tract is thereby decreased by introduction thereof. The present invention provides a method for preventing and treating obesity and obesity related metabolic syndrome, a pharmaceutical composition and diet supplement for prevention and treatment thereof, and modified probiotic strains usable for such purposes. The present invention provides a weight loss effect and shows that the absorption of fatty acids in the gastrointestinal tract is blocked by improving the characteristics of intestinal bacteria and transplanting them, thereby enabling the treatment of obesity.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: March 24, 2015
    Assignee: Jinis Biopharmaceuticals Co.
    Inventors: Hyeon Jin Kim, Seong Tshool Hong
  • Publication number: 20150079040
    Abstract: The invention provides probiotic bacteria and lysates thereof for use in methods of medical and cosmetic treatment. Use in the treatment of infections, including skin infections and methods involving regeneration or repair of the skin barrier are contemplated.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 19, 2015
    Inventors: Catherine O'Neill, Andrew McBain
  • Publication number: 20150079236
    Abstract: The present invention relates to food-grade bacteria strain being capable of removing mercury from an aqueous environment.
    Type: Application
    Filed: April 5, 2013
    Publication date: March 19, 2015
    Inventors: Jeremy Burton, Marc Monaches, Gregor Reid, Tamara Smokvina, Johan Van Hylckama Vlieg
  • Publication number: 20150079232
    Abstract: The present invention relates to mutants of lactic acid bacteria which are resistant to the antibiotic ampicillin and which were found to give an increased texture when grown in milk while maintaining the other growth properties of the parent strain. The present invention, furthermore, relates to compositions comprising such mutants, and to dairy products fermented with the lactic acid bacteria resistant to ampicillin.
    Type: Application
    Filed: April 23, 2013
    Publication date: March 19, 2015
    Applicant: Chr. Hansen A/S
    Inventors: Eric Johnsen, Kim Ib Soerensen, Annette Kibenich
  • Publication number: 20150079057
    Abstract: The present invention is related to the field of bioprotection, in particular to the strain of Lactobacillus rhamnosus CHCC5366 with accession no. DSM23035. Furthermore, the present invention concerns an antifungal composition comprising the strain, an antifungal composition comprising the strain and at least one strain of Lactobacillus paracasei, food, feed and pharmaceutical products comprising such an antifungal composition, a method of manufacturing such food, feed and pharmaceutical products, a method for reducing the content of yeasts and molds of such food, feed and pharmaceutical products and uses of the antifungal composition.
    Type: Application
    Filed: April 9, 2013
    Publication date: March 19, 2015
    Applicant: CHR. HANSEN A/S
    Inventors: Tina Hornbaek, Maike Lisberg, Silja Kej Diemer
  • Patent number: 8980611
    Abstract: Compositions and methods useful for reducing or eliminating the presence of pathogens in meat or meat products are disclosed. Administration of one or more lactic acid producing microorganisms to a live animal, to a carcass, to meat, to meat products, or in animal feed results in significant reductions in the amount of pathogens potentially harmful to humans when ingested. Synergistic effects can be achieved with the administration of multiple strains of microorganisms.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: March 17, 2015
    Assignee: Guardian Food Technologies, LLC
    Inventors: Douglas R. Ware, Mindy M. Brashears
  • Publication number: 20150072033
    Abstract: The present invention generally relates to the field of pro biotic micro-organisms, in particular to the field of non-replicating probiotic micro-organisms. Embodiments of the present invention relate to compositions comprising probiotic microorganisms that were rendered non-replicating by extrusion. Such compositions may be used to treat or prevent disorders that are related to a compromised immune system.
    Type: Application
    Filed: November 14, 2014
    Publication date: March 12, 2015
    Inventors: Annick Mercenier, Antoine Wermeille, Audrey Demont, Guenolee Prioult
  • Publication number: 20150064152
    Abstract: The present invention is related to the field of bioprotection, in particular to the strain of Lactobacillus paracasei CHCC14676 with accession no. DSM25612. Furthermore, the present invention concerns an antifungal composition comprising the strain, an antifungal composition comprising the strain and at least one strain of Lactobacillus rhamnosus, food, feed and pharmaceutical products comprising such an antifungal composition, a method of manufacturing such food, feed and pharmaceutical products, a method for reducing the content of yeasts and molds of such food, feed and pharmaceutical products and uses of the antifungal composition.
    Type: Application
    Filed: April 9, 2013
    Publication date: March 5, 2015
    Applicant: Chr. Hansen A/S
    Inventors: Tina Hornbaek, Maike Lisberg, Silja Kej Diemer
  • Patent number: 8961953
    Abstract: This invention relates to a preparation comprising N-acetyl-lactosamine and/or an oligosaccharide containing N-acetyl-lactosamine and a probiotic Lactobacillus sp. The invention extends to nutritional compositions comprising said preparation and to the use of the preparation in the prevention and treatment of pathogenic infections of the gastro-intestinal and upper respiratory tracts.
    Type: Grant
    Filed: February 24, 2009
    Date of Patent: February 24, 2015
    Assignee: Nestec S.A.
    Inventor: Norbert Sprenger
  • Publication number: 20150050254
    Abstract: A first aspect of the invention relates to a porcine lactic acid bacterial strain, wherein said bacterial strain is characterised by one or more of the following characteristics: (i) the ability to exhibit antimicrobial activity against E. coli; (ii) the ability to exhibit antimicrobial activity against S. enteritidis; (iii) the ability to suppress inflammation in IPEC cells induced by 12-0-tetradecaboylphorbol-13-acetate (PMA); (iv) the ability to block the attachment or invasion of IPEC cells by S. enteritidis; (v) the ability to block the attachment or invasion of IPEC cells by E. coli; (vi) the absence of antibiotic resistance to one or more antibiotics selected from the following: ampicillin; cefotaxime; chloramphenicol; erythromycin; gentamicin; tetracycline; vancomycin; metronizadole; nalidixic acid; and kanamycin; and (vii) the ability to exhibit heat stability when subjected to three cycles of heating, each cycle comprising heating at a temperature of 70° C. for a period of 15 minutes.
    Type: Application
    Filed: July 13, 2012
    Publication date: February 19, 2015
    Applicant: GT BIOLOGICS LTD
    Inventor: Denise Kelly
  • Publication number: 20150050255
    Abstract: New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower LDL-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation.
    Type: Application
    Filed: October 28, 2014
    Publication date: February 19, 2015
    Inventors: BELINDA VALLEJO GALLAND, AARÓN FERNANDO GONZÁLEZ CÓRDOVA, JÓSE CARLOS RODRÍGUEZ FIGUEROA
  • Patent number: 8951775
    Abstract: The present invention relates to the cosmetic use of an effective amount of at least one probiotic microorganism and/or a fraction thereof and/or a metabolite thereof, as an agent for treating and/or preventing oily skin or skin with an oily tendency and the associated skin disorders.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: February 10, 2015
    Assignees: L'Oreal, Nestec SA
    Inventors: Isabelle Castiel, Audrey Gueniche
  • Patent number: RE46718
    Abstract: The invention refers to a composition comprising one or more tannase-producing strains of Lactobacillus having the ability to adhere to the human intestinal mucosa in combination with tannin. New tannase-producing strains of Lactobacillus plantarum are a.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: February 20, 2018
    Assignee: Probi AB
    Inventors: Goran Molin, Siv Ahrné, Bengt Jeppsson
  • Patent number: RE48652
    Abstract: The present invention relates to a lactic acid bacterium isolated from human mother's milk, more precisely a Lactobacillus gasseri BNR17 strain that is isolated from Korean mother's milk and has excellent probiotic activity including acid resistance, bile acid resistance and antimicrobial activity and weight gaining inhibitory effect as well. Again, the Lactobacillus gasseri BNR17 of the present invention has excellent acid resistance, bile acid resistance, enteric absorption activity and antimicrobial activity against pathogenic microorganisms, in addition to the weight gaining inhibitory effect by synthesizing indigestible polysaccharides from monosaccharides included in food taken and releasing the synthesized polysaccharides out of the body.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: July 20, 2021
    Assignee: BIONEER CORPORATION
    Inventors: Ji Hee Kang, Byeung Il You, Sung Il Yun, Han Oh Park