Ester Of (hx)p=x(xh)(xh) (x Is Chalcogen) (e.g., Phosphate, Etc.) Patents (Class 514/143)
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Patent number: 5660858Abstract: This invention comprises pharmaceutical compositions consisting essentially of an oil-in-water emulsion containing a synthetic medium chain triglyceride in which is dissolved a therapeutically effective amount of a cyclosporin, phospholipid and optionally free fatty acid or a salt thereof, non-ionic surfactant, ionic surfactant, glycerol, salts, buffers, preservative, osmotic modifier and antioxidant.Type: GrantFiled: April 3, 1996Date of Patent: August 26, 1997Assignee: Research Triangle PharmaceuticalsInventors: Indu Parikh, Awadhesh Mishra
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Patent number: 5646133Abstract: An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small amount of a water soluble non-aromatic polyorganic acid or salt form thereof such as polyaspartic acid, particularly preferred with a molecular weight in the range of about 3000 to 40,000.Type: GrantFiled: March 14, 1996Date of Patent: July 8, 1997Assignee: Donlar CorporationInventor: J. Larry Sanders
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Patent number: 5627165Abstract: The composition and methods of synthesis of phosphorus prodrugs are described. These methods can be used to convert negatively charged phosphorous bearing drugs into neutrally charged; lipid soluble prodrugs which are able to passively diffuse into cells and into tissues in vivo. Prodrugs for a variety of antiviral and anti-leukemic agents are described.Type: GrantFiled: September 23, 1994Date of Patent: May 6, 1997Assignee: Drug Innovation & Design, Inc.Inventor: Arnold Glazier
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Patent number: 5627174Abstract: Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops, these compounds having the general structure: ##STR1## These Polar compounds are particularly useful for systemic control of pests.Type: GrantFiled: May 23, 1995Date of Patent: May 6, 1997Assignee: Monsanto CompanyInventors: Dennis P. Phillion, Peter G. Ruminski, Gopichand Yalamanchili
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Patent number: 5585249Abstract: Lipid bilayers which incorporate poly-3-hydroxybutyrate/polyphosphate ion channels. The ion channels are preferably purified polyhydroxybutyrate polyphosphate complexes extracted from organisms or prepared from the individual constituents which have been size selected. The bilayers are useful for testing the affect of various molecules and ions on the channel which correlates to the in vivo result. The bilayers are useful for transporting the channels into cells or other bilayers.Type: GrantFiled: October 3, 1994Date of Patent: December 17, 1996Assignee: Board of Trustees operating Michigan State UniversityInventor: Rosetta N. Reusch
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Patent number: 5583089Abstract: This invention provides a dry blend pesticide composition which contains a fungicidal bicarbonate salt ingredient, and a spreader-sticker ingredient which is a crystalline clathrate complex of a urea constituent and a normally liquid spreader sticker constituent such as a nonionic surfactant. In a preferred embodiment all of the composition ingredients are water-soluble, and the composition is readily dispersible in an aqueous medium to form a sprayable pesticide solution.Type: GrantFiled: May 9, 1995Date of Patent: December 10, 1996Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5541221Abstract: 3 and 4-substituted 2(5H)-furanone compounds influence the balance between bone production and bone resorption in mammals, including humans. The active compounds are administered to mammals, including humans, in an effective dose which ranges between 0.05 to 100 mg per kilogram, body weight, per day, for the purpose of influencing the balance between bone production and bone resorption, and particularly for treating osteoporosis.Type: GrantFiled: January 30, 1995Date of Patent: July 30, 1996Assignee: AllerganInventor: Michael E. Garst
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Patent number: 5505770Abstract: An antifouling agent characterized by containing one or more compounds represented by the following general formula (I) as an active ingredient: ##STR1## (wherein R.sub.1, R.sub.2 and R.sub.3 independently represent each a hydrogen atom, a halogen atom or an alkyl group carrying 1 to 30 carbon atoms; X represents an inorganic oxygen acid residue; n is from 1 to 4; m is from 0 to 3; and R.sub.4 represents a hydrogen atom or an alkyl or alkenyl group carrying 1 to 30 carbon atoms and optionally having an ether bond.Type: GrantFiled: April 29, 1994Date of Patent: April 9, 1996Assignee: Asahi Denka Kogyo Kabushiki KaishaInventors: Ryoji Kimura, Mitsuhiro Hamajima
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Patent number: 5453420Abstract: Garlic essence is produced by extracting garlic with ethanol and deodorized with phytic acid, added either during or after the extracting step. The garlic essence exhibits outstanding antibacterial action when added to or sprayed onto foods. It is used alone or in combination with .epsilon.-polylysine in the amount of 1-256 .mu.g/ml.Type: GrantFiled: August 19, 1993Date of Patent: September 26, 1995Inventor: Isao Sakai
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Patent number: 5451573Abstract: Substituted cyclohexane derivatives for the treatment of diseases Esters of cyclohexane derivatives of the formula I ##STR1## in which A--B, R.sup.3, R.sup.4, R.sup.5, Y and Z have the meanings indicated, for use as inhibitors of the glucose-6-phosphatase system of the liver in mammals are described. The compounds are suitable for the production of pharmaceutical preparations.Type: GrantFiled: September 7, 1993Date of Patent: September 19, 1995Assignee: Hoechst AktiengesellschaftInventors: Horst Hemmerle, Peter Schindler, Roland Utz, Robert Rippel, Andreas Herling
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Patent number: 5447923Abstract: Methods for the treatment of a human or lower animal subject having an H. pylori-mediated upper gastrointestinal disorder comprising administering to said subject a safe and effective amount of a diphenyl ether phosphate ester of the following formula: ##STR1## wherein n is an integer from 0 to 3, or a pharmaceutically-acceptable salt thereof.Type: GrantFiled: October 11, 1994Date of Patent: September 5, 1995Assignee: The Proctor & Gamble CompanyInventors: Carl E. Catrenich, Dennis G. A. Nelson
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Patent number: 5441983Abstract: A method for inhibiting cell infection by an enveloped virus, by administering to an infection site, a therapeutically effective amount of a calix(n)arene compound derivatized, at its ring positions meta to the bridge attachements to the ring, with polar substitutent having a terminal carboxylate, phosphate, or sulfonate groups, including esters and amides which are cleavable in vivo. The compound may be administered orally, or topically, e.g., for treatment of herpes virus.Type: GrantFiled: August 6, 1992Date of Patent: August 15, 1995Assignee: Genelabs IncorporatedInventors: Kou M. Hwang, You M. Qi, Su-Ying Liu, William Choy, Jen Chen
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Patent number: 5434144Abstract: The subject invention relates to methods of regulating skin wrinkles and/or atrophy in mammalian skin comprising topically applying to the skin of a mammal in need of treatment a composition comprising a safe and effective amount of a cyclic polyanionic polyol derivative having the structure: ##STR1## wherein n is an integer from 1 to 3; and each X is, independently, selected from the group consisting of OSO.sub.3.sup.-, OPO.sub.3.sup..dbd., SO.sub.3.sup.--, PO.sub.3.sup..dbd., CO.sub.2.sup.--, and OH; with at least 3 X's being other than OH.Type: GrantFiled: March 4, 1994Date of Patent: July 18, 1995Assignee: The Procter & Gamble CompanyInventors: Gerald B. Kasting, John M. Gardlik
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Patent number: 5432148Abstract: This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an aqueous dispersion. The constituents include (1) an ingredient such as urea which slow-releases ammonia under aqueous alkaline pH conditions; and (2) an alkali metal bicarbonate ingredient which imparts alkalinity to the aqueous dispersion, and provides bicarbonate ions for combination with the released ammonium ions. A spreader-sticker ingredient is included to maintain the ingredients in contact with plant foliage over an extended period after application.Type: GrantFiled: December 7, 1994Date of Patent: July 11, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5425952Abstract: This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an aqueous dispersion. The constituents include (1) an ingredient such as urea which slow-releases ammonia under aqueous alkaline pH conditions; and (2) an alkali metal bicarbonate ingredient which imparts alkalinity to the aqueous dispersion, and provides bicarbonate ions for combination with the released ammonium ions. A spreader-sticker ingredient is included to maintain the ingredients in contact with plant foliage over an extended period after application.Type: GrantFiled: October 13, 1993Date of Patent: June 20, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5409885Abstract: Stable and flowable aqueous dispersions of at least one water-insoluble material are formulated by dispersing such water-insoluble material, e.g., solid particulates of a plant protection compound, into a homogeneous, stable and flowable aqueous composition that includes (1) at least one water-soluble derivative of a plant protection active agent bearing at least one ionizable functional group and at least one hydrophilic functional group, (2) at least one nonionic surface-active agent and/or at least one aliphatic, cycloaliphatic or arylaliphatic alcohol having from 4 to 15 carbon atoms, and (3) water, this composition exhibiting optical birefringence and a yield point of at least 0.1 pascal.Type: GrantFiled: July 9, 1992Date of Patent: April 25, 1995Assignee: Rhone-Poulenc ChimieInventors: Paul-Joel Derian, Gilles Guerin, Philippe Jost
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Patent number: 5395828Abstract: A compound of the formula (I) ##STR1## in which R.sub.1 is e.g. phosphate,R.sub.2 is e.g. phosphate or OH, andR.sub.4 is e.g. ##STR2## are suitable Calcium antagonists and useful e.g. for the treatment of cardio-vascular diseases.Type: GrantFiled: June 24, 1992Date of Patent: March 7, 1995Assignee: Hoechst AktiengesellschaftInventors: Werner Schiebler, Elke Deckert, Erik Dreef, Gijs V. D. Marel, Jacques V. Boom
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Patent number: 5260051Abstract: The invention relates to novel compositions, in particular personal product compositions containing phosphate ester surfactants in which a portion of the surfactant molecule has a so-called "benefit reagent" function. It is believed that this benefit reagent portion comes to play when the surfactant is metabolized or hydrolyzed.Type: GrantFiled: December 17, 1990Date of Patent: November 9, 1993Assignee: Lever Brothers Company, Division of Conopco, Inc.Inventor: Suk H. Cho
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Patent number: 5260287Abstract: Compositions and methods for protecting the luminal lining against gastric acid challenge are disclosed. The compositions provide effective anti-ulcer preparations which include phosphorylated alcohol. Phosphorylated alcohols comprise the active anti-ulcerogenic ingredient of the described therapeutic formulations. The preparation of unique linear and cyclic polyphosphorylated alcohols and methods of using same to protect the stomach luminal lining against acid challenge are also disclosed. Inositol hexaphosphate and mannitol hexaphosphate are demonstrated to provide therapeutic value in the treatment and prevention of gastro-erosive disease precipitated by exposure of biological tissues to highly acidic substances, for example, the gastric digestive acids. While inositol hexaphosphate alone at subthreshold concentrations provides a small gastro-protective activity, a combination of inositol hexaphosphate (at subthreshold concentrations) with polyvalent cations, such as Au.sup.+3 or Bi.sup.Type: GrantFiled: May 11, 1992Date of Patent: November 9, 1993Assignee: Board of Regents, The University of Texas SystemInventors: Jose C. Barreto, Lenard M. Lichtenberger
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Patent number: 5198012Abstract: A biocide composition comprises an effective amount of a biocide and an effective amount of a biocide activator selected from the group consisting of an alkyl phosphate, an alkenyl phosphate, a hydroxyalkyl phosphate, a polyoxyalkylene alkyl ether phosphate, a salt thereof, a polyoxyalkylene alkenyl ether phosphate, a salt thereof, a polyoxyalkylene hydroxyalkyl ether phosphate and a salt thereof.Type: GrantFiled: May 21, 1991Date of Patent: March 30, 1993Assignee: Kao CorporationInventor: Tetsuji Iwasaki
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Patent number: 5147859Abstract: Complexes of glycyrrhetinic acid with phospholipids are described in which the molar ratio of phospholipids to glycyrrhetinic acid is from 0.5 to 2. The phospholipids are selected from the group consisting of soy lecithins, phospholipids from bovine or swine brain or cutis, phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine in which the acyl groups can be the same or different and are mostly derived from palmitic, stearic, oleic, linoleic, linolenic acids. The phospholipid may be soy phosphatidylcholine or distearoylphosphatidylcholine. Pharmaceutical compositions and a method for producing anti-inflammatory, antiulcer and healing effects in an animal are also described.Type: GrantFiled: January 15, 1991Date of Patent: September 15, 1992Assignee: Indena S.p.A.Inventors: Ezio Bombardelli, Gianfranco Patri, Roberto Pozzi
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Patent number: 5143739Abstract: Salmonella and other bacteria can be removed, reduced or retarded on poultry carcasses by treating poultry with a treatment solution containing an alkali metal orthophosphate, e.g., trisodium orthophosphate.Type: GrantFiled: June 7, 1991Date of Patent: September 1, 1992Assignee: Rhone-Poulenc Inc.Inventors: Fredric G. Bender, Eugene Brotsky
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Patent number: 5116992Abstract: The invention relates to glycerol derivatives of general formulae Ia, Ib and Ic ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, A and Y stand for various substituents, to a preparation process of said compounds and to therapeutical compositions containing the same.Type: GrantFiled: December 19, 1990Date of Patent: May 26, 1992Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)Inventors: Pierre Braquet, Colette Broquet, Benedicte Vandamme, Paola Principe-Nicolas
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Patent number: 5091193Abstract: A composition for preventing or treating diaper rash comprising an effective amount of zinc oxide and at least one antienzyme sufficient to treat or prevent diaper rash and an inert pharmaceutical carrier and a method of treating or preventing diaper rash on new-born babies.Type: GrantFiled: August 21, 1990Date of Patent: February 25, 1992Assignee: Roussel UclafInventors: Odile Enjolras, Hugues Noel
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Patent number: 5082833Abstract: A method for moderating the rate of cellular mitosis in a living mammalian tissue having a pathologically elevated rate of cellular mitosis sensitive to treatment with a solution below which comprises perfusing said tissue under mitotic growth conditions with a safe and effective amount and concentration of a composition consisting essentially of a) inositol hexaphosphate or a physiologically acceptable salt thereof; and b) a source of inositol or a physiologically acceptable salt thereof, for a period of time sufficient to moderate the elevated rate of cellular mitosis to a normal, non-pathological rate for said tissue. The method is useful in human and mammalian diseases wherein NK cell activity is altered in the laboratory, e.g. tumors, other cancers including leukemia, immunosuppressed individuals (AIDS and transplant recipients), and in viral, fungal or protozoal infections.Type: GrantFiled: June 30, 1988Date of Patent: January 21, 1992Inventor: Abulkalam M. Shamsuddin
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Patent number: 5045311Abstract: The invention relates to an emulsifiable microemulsion concentrate containing a phophoric acid ester and/or thiophosphoric acid ester as active ingredient. In addition to 20 to 80% by weight of active ingredient, the composition comprises: 7 to 70% by weight of a nonionic surface active agent, preferably a block copolymer with a molecular weight of 1000 to 10000 formed from polyethylene oxide and polypropylene oxide, an alkylphenol polyglycol ether, ethoxylated fatty alcohol or a mixture of nonionic surface active agents; 2 to 50% by weight of water; if desired, 1 to 50% by weight of a co-surfactant, preferably C.sub.1-8 straight or branched chain and/or cyclic alcohol, C.sub.3-8 straight or branched chain and/or cyclic ketone, esters of C.sub.1-6 fatty acids with C.sub.1-6 alcohols or the mixture thereof; and if desired, 15 to 30% by weight of a water-immiscible organic solvent.Type: GrantFiled: May 12, 1989Date of Patent: September 3, 1991Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.Inventors: Janos Pinter, Josefne Pal, Eva Kiss, Erzsebet Shuszler, Sandor Angyan, Laszlo Pap, Andras Szego, Tamas Detre, Tamasne Marmarosi
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Patent number: 5043008Abstract: A biocide composition comprises an effective amount of a biocide and an effective amount of a biocide activator selected from the group consisting of an alkyl phosphate, an alkenyl phosphate, a hydroxyalkyl phosphate, a polyoxyalkylene alkyl ether phosphate, a salt thereof, a polyoxyalkylene alkenyl ether phosphate, a salt thereof, a polyoxyalkylene hydroxyalkyl ether phosphate and a salt thereof.Type: GrantFiled: October 25, 1989Date of Patent: August 27, 1991Assignee: Kao CorporationInventor: Tetsuji Iwasaki
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Patent number: 5041429Abstract: Phytic acid or at least one of its salts is used as an effective component for cell activators in a hypoxic state, circulatory ameliorators, dementia remedies and edible compositions.Type: GrantFiled: May 22, 1989Date of Patent: August 20, 1991Assignee: Sanwa Kagaku Kenkyusho Co., Ltd.Inventors: Kiichi Sawai, Masayasu Kurono, Hiromoto Asai, Takahiko Mitani, Motohide Hayashi, Tunematu Suzuki, Naohisa Ninomiya
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Patent number: 4976769Abstract: A biocide composition comprises an effective amount of a biocide and an effective amount of a biocide activator selected from the group consisting of an alkyl phosphate, an alkenyl phosphate, a hydroxyalkyl, phosphate, a polyoxyalkylene alkyl ether phosphate, a salt thereof, a polyoxyalkylene alkenyl ether phosphate, a salt thereof, a polyoxyalkylene hydroxyalkyl ether phosphate and a salt thereof.Type: GrantFiled: October 18, 1989Date of Patent: December 11, 1990Assignee: Kao CorporationInventor: Tetsuji Iwasaki
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Patent number: 4973583Abstract: Pesticidal O-halogenocyclobutyl S-alkyl (di) thiophosph(on)ates of the formula ##STR1## in which x represents oxygen or sulphur,p represents zero, one or two,m represents zero, one or two,n represents 2, 3 or 4R.sup.1 represents alkyl, alkoxy which is optionally interrupted by oxygen or sulphur and can be substituted by halogen, or alkenyloxy, alkinyloxy, heterocyclyl-alkoxy or cycloalkoxy which is optionally substituted by alkyl and/or halogen,R.sup.2 represents alkyl which is optionally interrupted by oxygen or sulphur and can be substituted by halogen, or alkenyl, alkinyl or heterocyclyl-alkyl andR.sup.3 represents hydrogen or alkyl.Type: GrantFiled: June 1, 1989Date of Patent: November 27, 1990Assignee: Bayer AktiengesellschaftInventors: Bernd-Wieland Kruger, Dietmar Bielefeldt, Karl-Rudolf Gassen, Bernhard Homeyer, Benedikt Becker, Hans-Detlef Matthaei, Wilhelm Stendel
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Patent number: 4944950Abstract: The present invention relates to a bait composition for insects comprising a mixture of cucumbers, eggs, potatoes, sugar and honey. The bait composition can incorporate an insecticidal mixture of boric acid, mercuric chloride, arsenic trioxide and aluminum sulfate.Type: GrantFiled: April 26, 1989Date of Patent: July 31, 1990Inventor: Bronislava Sakharova
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Patent number: 4888049Abstract: A biocide is strengthened in the biocidal effect with a branched guaternary ammonium salt having a group of ##STR1## in which R5 is an alkyl or alkenyl having 4 to 18 carbon atoms and R6 is an alkyl or alkenyl having 2 to 16 carbon atoms.Type: GrantFiled: May 29, 1987Date of Patent: December 19, 1989Assignee: Kao CorporationInventors: Tetsuji Iwasaki, Hitoshi Hosokawa
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Patent number: 4868163Abstract: A transparent or semitransparent jelly-like cosmetic composition comprises a monoalkyl phosphate having a .beta.-branched alkyl group, water, an oil which is liquid at room temperature, and an alcohol.The cosmetic composition is highly safe and has good moisturizing effect. Therefore, it can be used as a base for a massage cream, a body treatment, a hand cream, a hair conditioner and the like.Type: GrantFiled: September 30, 1987Date of Patent: September 19, 1989Assignee: Kao CorporationInventors: Hiroko Takei, Toshiyuki Suzuki, Tsuyoshi Otomo, Ichiro Tokimitsu
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Patent number: 4844734Abstract: A granular pesticide containing a surfactant as a synergist can be prepared by countercurrent spray drying under specified conditions. The obtained granular pesticide exhibits excellent fluidity and storage stability and is excellent in wettability and disintegratability.Type: GrantFiled: May 29, 1987Date of Patent: July 4, 1989Assignee: Kao CorporationInventors: Tetsuji Iwasaki, Takuo Goto, Tadao Matsumoto
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Patent number: 4812443Abstract: A medicament containing a compound of the formula ##STR1## wherein ##STR2## is a trans-isoprene unit, ##STR3## is a cis-isoprene unit, and n is an integer of from 12 to 18, or a pharmaceutically acceptable ester thereof.The medicament is useful for the treatment of anemia, particularly aplastic anemia.Type: GrantFiled: June 24, 1985Date of Patent: March 14, 1989Assignee: Kuraray Co., Ltd.Inventors: Fumimaro Takak, Akio Urabe, Michiya Shimamura, Masao Mizuno
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Patent number: 4770694Abstract: A water-insoluble biocide component can be effectively dispersed in water by using as a dispersant a phosphoric acid ester salt of a nonionic surfactant.Type: GrantFiled: March 10, 1982Date of Patent: September 13, 1988Assignee: Kao Soap Co., Ltd.Inventors: Tesuji Iwasaki, Tsuneyuki Takeno, Yukio Yamamoto
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Patent number: 4762547Abstract: A biocide is enhanced in the effect by applying an esterase to a plant stem, leaves or an insect in advance to or together with the application of the biocide. The esterase decomposes the waxy outer layers of plants and insects.Type: GrantFiled: January 3, 1986Date of Patent: August 9, 1988Assignee: Kao CorporationInventors: Tetsuji Iwasaki, Yuichi Hioki
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Patent number: 4731240Abstract: The present invention relates to the art of veterinary science. The preparation for prevention and treatment of myiases of animals comprises the following components, percent by mass:an insecticide exhibiting a larvicidal effect: 1.4 to 2.3a 5-10% ethanolic solution of polyvinylbutyral and a resol-type phenolformaldehyde resin taken in a ratio of 1:10-45: 16 to 35.0a plastifying agent improving elasticity of the resulting polymeric film: 1.0 to 20.0an antibiotic: 0.1 to 0.7an organic solvent: the balance.Type: GrantFiled: June 5, 1986Date of Patent: March 15, 1988Inventors: Alexandr A. Zakomyrdin, Mark A. Simetsky, Elena I. Pilipets, Vladimir M. Repin, Vitaly I. Ilyaschenko, Dmitry G. Klientovsky, Ljudmila I. Golik, Viktor A. Samkin, Nina P. Kuznetsova
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Patent number: 4710494Abstract: Benzylbisthiophosphates of the formula ##STR1## where R is straight-chain or branched alkyl of 3 to 5 carbon atoms, their manufacture, and their use as pesticides.Type: GrantFiled: May 28, 1986Date of Patent: December 1, 1987Inventors: Rainer Buerstinghaus, Heinrich Adolphi
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Patent number: 4661509Abstract: A method of improving the levels of formed blood elements in a patient having disease or therapy induced leukopenia comprising administering to said patient a therapeutically effective amount of a pharmaceutically acceptable, water or lipid soluble tertiary or quaternary amine having cholinergic or anticholinesterase activity.Type: GrantFiled: February 21, 1984Date of Patent: April 28, 1987Inventors: Arnold Z. Gordon, Arthur H. Rossof
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Patent number: 4659701Abstract: A vinylbenzyl phosphate of the formula I ##STR1## where A, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8 and R.sup.9 have the meanings stated in the description, and their preparation are described. The substances are useful for the treatment of disorders.Type: GrantFiled: September 20, 1985Date of Patent: April 21, 1987Assignee: BASF AktiengesellschaftInventors: Hans-Heiner Wuest, Fritz-Frieder Frickel, Axel Nuerrenbach
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Patent number: 4596796Abstract: A dithiolphosphoric acid ester of the formula, ##STR1## wherein A is sec-butyl or tert-butyl group, and B is iso-propyl, n-butyl, iso-butyl, sec-butyl or tert-butyl group, which is useful as a soil pesticidal composition for pests in soil.Type: GrantFiled: September 10, 1984Date of Patent: June 24, 1986Assignee: Sumitomo Chemical Company, LimitedInventors: Haruyasu Yamamoto, Kiyoshi Kasamatsu, Takayuki Okabe
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Patent number: 4536519Abstract: Disclosed herein is an emulsifying agent comprising (a) a partially or completely neutralized product, with a basic substance, of a phosphoric acid ester which contains a phosphoric acid monoester represented by the general formula (I) and a phosphoric acid diester represented by the general formula (II) from 100:0 to 70:30 molar ratio: ##STR1## wherein R.sub.1 and R.sub.4 represent individually a linear alkyl group or a linear alkenyl group of 10-22 carbon atoms or a branched alkyl group of 12-24 carbon atoms, R.sub.2 and R.sub.3 represent individually an ethylene group or a propylene group, and m and n represent individually a number of 0-30, and (b) a nonionic surfactant with HLB of 6 or less. Emulsified cosmetics comprising (a) the neutralized product of the phosphoric acid ester, (b) a nonionic surfactant with HLB of 6 or less, (c) an oily substrate, and (d) water is also disclosed.Type: GrantFiled: June 9, 1982Date of Patent: August 20, 1985Assignee: Kao Soap Co., Ltd.Inventors: Toshiyuki Suzuki, Tohru Nakamura, Hisao Tsutsumi
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Patent number: 4535077Abstract: O-ethyl S,S-dialkyl phosphorodithioates of the formula: ##STR1## in which one of R and R.sup.1 is an s-butyl group and the other of R and R.sup.1 is s-butyl or t-butyl, exhibiting high levels of activity against soil borne insects and nematodes and low phytotoxicity, are described and exemplified.Type: GrantFiled: December 8, 1983Date of Patent: August 13, 1985Assignee: FMC CorporationInventor: Mohamed A. H. Fahmy
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Patent number: 4507288Abstract: The compounds of formula (I) ##STR1## wherein R.sub.1 is hydrogen or an alkyl radical containing one to six carbon atoms and R.sub.2 is an alkyl radical containing one to six carbon atoms possess markedly increased activity against malaria-causing parasites. Pharmaceutical compositions and method of treatment of subjects with malaria are also disclosed.Type: GrantFiled: September 16, 1983Date of Patent: March 26, 1985Assignee: Smithkline Beckman CorporationInventor: Jean F. Rossignol