Abstract: A sulfenamide vulcanization accelerator is provided that acts satisfactorily slowly on a vulcanization reaction, produces no carcinogenic nitrosamine, and is free from environmental hygiene problems such as bioaccumulation. Also provided is an N-alkyl-N-t-butylbenzothiazole-2-sulfenamide represented by formula [I]. The vulcanization accelerator is a vulcanization accelerator for rubber, containing this compound. Furthermore provided is a process for producing the vulcanization accelerator. wherein R represents methyl, ethyl, n-propyl, or n-butyl.

Abstract: A sulfenamide vulcanization accelerator is provided that acts satisfactorily slowly on a vulcanization reaction, produces no carcinogenic nitrosamine, and is free from environmental hygiene problems such as bioaccumulation. Also provided is an N-alkyl-N-t-butylbenzothiazole-2-sulfenamide represented by formula [I]. The vulcanization accelerator is a vulcanization accelerator for rubber, containing this compound. Furthermore provided is a process for producing the vulcanization accelerator. wherein R represents methyl, ethyl, n-propyl, or n-butyl.

Abstract: Compounds represented by formula (I): are inhibitors of gut microsomal triglyceride transfer protein. Such compounds are useful in treating diseases or conditions such as diabetes and obesity, along with patients are risk for developing such diseases or conditions.

Abstract: Modulators of PPAR? activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity.

Abstract: The current invention discloses hydroxyamidino derivatives useful as nitric oxide synthase inhibitors.

Abstract: Biotin, fluorescent and chemiluminescent labeled vitamin D compounds are disclosed as well as their use in assays for the presence of vitamin D, its metabolites and vitamin D analogs in biological fluids.

Abstract: Novel mono- and bis-benzothiazole sulfenamide compounds based on primary amines are provided which may be employed as rubber vulcanization accelerators having excellent scorch safety. Vulcanizable rubber compositions containing rubber, sulfur and the novel benzothiazole sulfenamide compounds are also provided.

Abstract: Antiretroviral compounds (which are effective, for example, against HIV) of the formula I ##STR1## in which R.sub.

Abstract: The process for the preparation of benzothiazolyl-2-sulphenamides, by reacting a 2-mercaptobenzothiazole or dibenzothiazolyl 2,2'-disulphide with a primary or secondary aliphatic or cycloaliphatic amine in the presence of hydrogen peroxide as oxidizing agent in an aqueous medium is distinguished in that an aqueous hydrogen peroxide solution is metered at a temperature in the range from 30.degree. to 70.degree. C. into an aqueous suspension of the respective amine and the 2-mercaptobenzothiazole or dibenzothiazolyl 2,2'-disulphide in a ratio in the range between 1.0 and 1.5 mol of amine per mole of 2-mercaptobenzothiazole or per equivalent of dibenzothiazolyl 2,2'-disulphide, preferably in a quantity of below 1.35 mol per mole of 2-mercaptobenzothiazole or per equivalent of dibenzothiazolyl 2,2'-disulphide over a period of at least 60 minutes. The total quantity of water in the reaction mixture should not exceed 1500 g per mole of 2-mercaptobenzothiazole.

Abstract: Benzothiazole sulphene amides are obtained from dibenzothiazolyl disulphide and water-soluble amines in the absence of an oxidizing agent and in the presence of aqueous alkali in a high yield and with very good stability in storage by placing the amine solution in water and simultaneously adding dibenzothiazolyl disulphide and aqueous alkali from separate storage vessels.

Abstract: An improved work-up of aqueous mother liquors which originate from the oxidative preparation of benzothiazolylsulphenamides and which contain unreacted amine or a low-boiling alcohol employed as solubilizer, or both, the work-up being carried out in such a fashion that the mother liquor is saturated by additives until two phases form, the phases are separated from one another, the aqueous phase is extracted with further alcohol or amine, amine, alcohol and the extracted components are isolated from the combined organic phases, and amine or alcohol dissolved in the aqueous phase is removed therefrom by distillation.

Abstract: Benzothiazolesulphenamides can be prepared in high yield and purity from dibenzothiazolyl disulphide and a primary or secondary amine in the absence of an oxidizing agent in a water-immiscible organic solvent and in the presence of aqueous alkali by presenting a solution of the amine in the organic solvent and adding dibenzothiazolyl disulphide and aqueous alkali either simultaneously or in succession.

Abstract: There is disclosed a process for the preparation of N,N-diisopropylbenzothiazyl-2-sulfenamide which comprises contacting an aqueous mixture of diisopropylamine and 2-mercaptobenzothiazole with an oxidizing agent in the presence of sufficient acid to neutralize the excess base, if any, in the oxidizing agent wherein the molar ratio of diisopropylamine to 2-mercaptobenzothiazole is at least 1.5 to 1.

Abstract: This invention relates to a process for the production of benzothiazolyl sulphenamides corresponding to the following general formula: ##STR1## in which a corresponding 2-mercaptobenzothiazole or a dibenzothiazolyl-2,2'-disulphide is reacted with a primary or secondary amine at temperatures of from 0 to 100.degree. C. in the presence of ammonia, oxygen, a copper-containing catalyst and a reaction medium containing an excess of the primary or secondary amine or of a mixture of that amine with water and/or a water-miscible organic solvent.Benzothiazolyl sulphenamides are valuable vulcanization accelerators.

Abstract: A process for the preparation of benzothiazole-sulfenamides in which a benzothiazyl disulfide is reacted with a mixture comprising an amine halogenhydrate and an N-halogen amine derivative.

Abstract: Sulfenimides are prepared by electrolytic oxidation of organic disulfides or mercaptans and imides. The electrolytic oxidation is accelerated by a halide compound.

Abstract: Thiazolesulphenamides, useful as rubber vulcanization accelerators, are made by reaction of a 2-mercapto-thiazole or a 2,2'-dithiazolyl disulphide with ammonia or a primary or secondary amine in the presence of oxygen and a copper catalyst of specified kind.