Two Of The Cyclos Share At Least Three Ring Members, Or A Ring Carbon Is Shared By Three Of The Cyclos (e.g., Bridged, Peri-fused, Etc.) Patents (Class 548/419)
  • Patent number: 9029566
    Abstract: An epoxide agent for an epoxy resin system, the epoxide agent comprising at least one non-acid functional rosin moiety and at least one epoxide moiety. Another embodiment is a curing agent for an epoxy resin system comprising at least one non-acid functional rosin moiety and at least one moiety that is reactive with an epoxy.
    Type: Grant
    Filed: September 16, 2009
    Date of Patent: May 12, 2015
    Assignee: Washington State University
    Inventors: Jinwen Zhang, Xiaoqing Liu, Ming Xian
  • Publication number: 20150073092
    Abstract: Methods for forming rosin-derived cationic compounds are provided. The method can include attaching a cationic group to a conjugated diene on a hydrophenathrene-based ring of a resin acid (e.g., levopimaric acid, abietic acid, dehydroabietic acid, or a mixture thereof) to form a rosin-derived cationic compound. Attaching the cationic group to the conjugated diene on the hydrophenathrene-based ring of the resin acid can be achieved via a Diels-Alder reaction of a dienophile with the hydrophenathrene-based ring of the resin acid. Rosin-derived cationic compounds are also provided. The rosin-derived cationic compound can include a cationic group attached to a conjugated diene on a hydrophenathrene-based ring of a resin acid, wherein the rosin-derived cationic compound further comprises a carboxylic acid group.
    Type: Application
    Filed: November 17, 2014
    Publication date: March 12, 2015
    Inventors: Chuanbing Tang, Jifu Wang, Alan W. Decho, Yung Pin Chen
  • Publication number: 20150064123
    Abstract: The present invention relates to ophthalmic and non-ophthalmic systems with blue light filtering and Yellowness Index ranges. UV and IR filtering are also included. Industrial applications are also outlined in the invention.
    Type: Application
    Filed: September 25, 2014
    Publication date: March 5, 2015
    Inventors: Andrew W. Ishak, Sean P. McGinnis, Ronald D. Blum, Michael B. Packard
  • Publication number: 20150057326
    Abstract: A method of synthesizing cycloalkanyl[b]indoles, as well as related cycloalkanyl[b]benzofurans and cycloalkanyl[b]benzothiophenes is provided. The method is a single, multicomponent reaction that combines (1) an indole, benzofuran, or benzothiopene, (2) an aldehyde, ketone, or ketal, and (3) a diene in the presence of an acid, in particular a Ga(III) or In(III) salt. Compositions and methods of using these compounds to stimulate secretion and/or production of glucagon-like peptide-1 or inhibit the activity of Calcitonin Gene-Related Peptide receptor are also provided.
    Type: Application
    Filed: November 10, 2014
    Publication date: February 26, 2015
    Applicant: Trustees of Dartmouth College
    Inventor: Jimmy Wu
  • Publication number: 20140361259
    Abstract: An arylamine-based compound is represented by Formula 1 below. The arylamine-based compound is included in an organic light emitting diode.
    Type: Application
    Filed: October 23, 2013
    Publication date: December 11, 2014
    Applicant: SAMSUNG DISPLAY CO., LTD.
    Inventors: Seok-Hwan Hwang, Young-Kook Kim, Hye-Jin Jung, Jun-Ha Park, Eun-Young Lee, Jin-O Lim, Sang-Hyun Han, Eun-Jae Jeong, Soo-Yon Kim, Jong-Hyuk Lee
  • Publication number: 20140167028
    Abstract: The present invention provides a novel aminoindolo[3,2,1-jk]carbazole compound having a good film-forming property and provides an organic light-emitting device including the compound. Provided is the aminoindolo[3,2,1-jk]carbazole compound represented by Formula [1] according to Claim 1. In Formula [1], l represents an integer of 1 to 3; n and m each independently represent an integer of 0 to 2; and R1 to R32 represent hydrogen atom, alkyl groups having 1 to 8 carbon atoms or fluorine atoms, wherein the alkyl groups may contain fluorine atoms.
    Type: Application
    Filed: July 10, 2012
    Publication date: June 19, 2014
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Takeshi Sekiguchi, Hiroki Ohrui, Masanori Muratsubaki
  • Publication number: 20140163174
    Abstract: Methods for forming rosin-derived cationic compounds are provided. The method can include attaching a cationic group to a conjugated diene on a hydrophenathrene-based ring of a resin acid (e.g., levopimaric acid, abietic acid, dehydroabietic acid, or a mixture thereof) to form a rosin-derived cationic compound. Attaching the cationic group to the conjugated diene on the hydrophenathrene-based ring of the resin acid can be achieved via a Diels-Alder reaction of a dienophile with the hydrophenathrene-based ring of the resin acid. Rosin-derived cationic compounds are also provided. The rosin-derived cationic compound can include a cationic group attached to a conjugated diene on a hydrophenathrene-based ring of a resin acid, wherein the rosin-derived cationic compound further comprises a carboxylic acid group.
    Type: Application
    Filed: December 10, 2013
    Publication date: June 12, 2014
    Inventors: Chuanbing Tang, Jifu Wang, Alan W. Decho, Yung Pin Chen
  • Publication number: 20140034914
    Abstract: An organic electroluminescent element comprising a substrate; a pair of electrodes including an anode and a cathode, disposed on the substrate; and at least one organic layer including a light emitting layer, disposed between the electrodes, wherein the light emitting layer includes a compound represented by the following general formula: wherein: R1, R2, and R19; R11 to R18; and A1 to A4 are as defined in the specification.
    Type: Application
    Filed: January 23, 2013
    Publication date: February 6, 2014
    Applicant: UDC Ireland Limited
    Inventors: Saki TAKADA, Yosuke YAMAMOTO, Kousuke WATANABE, Yuichiro ITAI
  • Patent number: 8628864
    Abstract: There is provided an indolo[3,2,1-jk]carbazole compound having an excellent membrane property, a high T1 energy, and a deep HOMO level. There is also provided an organic light-emitting device that contains the indolo[3,2,1-jk]carbazole compound. There is provided an indolo[3,2,1-jk]carbazole compound having a high T1 energy and a deep HOMO level.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: January 14, 2014
    Assignee: Canon Kabushiki Kaisha
    Inventors: Shigemoto Abe, Jun Kamatani, Kengo Kishino
  • Publication number: 20130320310
    Abstract: An organic electroluminescent element comprising: a substrate; a pair of electrodes including an anode and a cathode, disposed on the substrate; and at least one organic layer including a light emitting layer, disposed between the electrodes. At least one of the organic layer contains a compound of general formula (1): A-(B)n-D, wherein A, D, and B represent groups of the following general formulas (2), (3), and (4) respectively; n represents 0 or 1; and when n is 0, A and D are not symmetrical about a point to each other, including the binding sites: wherein XA1 to XA11, XD1 to XD11, and XB1 to XB11 are as defined in the specification.
    Type: Application
    Filed: February 26, 2013
    Publication date: December 5, 2013
    Applicant: UDC Ireland Limited
    Inventors: Yosuke Yamamoto, Kousuke Watanabe, Yuichiro Itai
  • Publication number: 20130200359
    Abstract: The present invention relates to compounds of the formula (1) and (2) which are suitable for use in electronic devices, in particular organic electroluminescent devices.
    Type: Application
    Filed: September 16, 2011
    Publication date: August 8, 2013
    Applicant: Merck Patent GmbH
    Inventors: Philipp Stoessel, Dominik Joosten, Arne Besing
  • Publication number: 20130190511
    Abstract: The present invention provides methods for chemically synthesizing naturally-occurring alkaloids, for example, Flindersia alkaloids, and their analogs and derivatives. Generally, the precursor borrerine is synthesized from tryptamine in the presence of an alkylating agent, an acylating agent and a reducing agent and dimerized in the presence of an acid, for example, tetrafluoroacetic acid, hydrochloric acid or acetic acid to yield the products. Analog and derivative compounds are produced by derivatizing one or more of the tryptamine, alkylating agent or acylating agent. Also provided are the synthetic alkaloids and derivatives and analogs thereof produced by the synthetic methods.
    Type: Application
    Filed: January 18, 2013
    Publication date: July 25, 2013
    Inventors: Jeremy A. May, Ravikrishna Vallakati
  • Patent number: 8470869
    Abstract: The present invention relates to new salts of perindopril, particularly to a new calcium salt and new amine salts of perindopril, to a process for their preparation and to a pharmaceutical formulations containing the new salts.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: June 25, 2013
    Assignee: KRKA, Tovarna Zdravil D.D. Novo Mesto
    Inventors: Marjo Merslavic, Sergeja Bombek, Urska Gojak, Matej Smrkolj, Rok Zupet
  • Publication number: 20120214950
    Abstract: Methods for forming rosin-derived cationic compounds are provided. The method can include attaching a cationic group to a conjugated diene on a hydrophenathrene-based ring of a resin acid (e.g., levopimaric acid, abietic acid, dehydroabietic acid, or a mixture thereof) to form a rosin-derived cationic compound. Attaching the cationic group to the conjugated diene on the hydrophenathrene-based ring of the resin acid can be achieved via a Diels-Alder reaction of a dienophile with the hydrophenathrene-based ring of the resin acid. Rosin-derived cationic compounds are also provided. The rosin-derived cationic compound can include a cationic group attached to a conjugated diene on a hydrophenathrene-based ring of a resin acid, wherein the rosin-derived cationic compound further comprises a carboxylic acid group.
    Type: Application
    Filed: February 15, 2012
    Publication date: August 23, 2012
    Applicant: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Chuanbing Tang, Jifu Wang, Alan W. Decho, Yung Pin Chen
  • Publication number: 20120075273
    Abstract: There is provided an indolo[3,2,1-jk]carbazole compound having an excellent membrane property, a high T1 energy, and a deep HOMO level. There is also provided an organic light-emitting device that contains the indolo[3,2,1-jk]carbazole compound. There is provided an indolo[3,2,1-jk]carbazole compound having a high T1 energy and a deep HOMO level.
    Type: Application
    Filed: September 20, 2011
    Publication date: March 29, 2012
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Shigemoto Abe, Jun Kamatani, Kengo Kishino
  • Patent number: 7994312
    Abstract: A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting group, with (ii) a metal salt under basic conditions to produce the metalloporphyrin. Products produced by such methods and intermediates useful for carrying out such methods are also described.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: August 9, 2011
    Assignee: North Carolina State University
    Inventors: Jonathan S. Lindsey, Dilek Dogutan Kiper
  • Publication number: 20110172440
    Abstract: An epoxide agent for an epoxy resin system, the epoxide agent comprising at least one non-acid functional rosin moiety and at least one epoxide moiety. Another embodiment is a curing agent for an epoxy resin system comprising at least one non-acid functional rosin moiety and at least one moiety that is reactive with an epoxy.
    Type: Application
    Filed: September 16, 2009
    Publication date: July 14, 2011
    Inventors: Jinwen Zhang, Xiaoqing Liu, Ming Xian
  • Patent number: 7700765
    Abstract: There is provided an oligopeptide compound comprising: (a) at least one nitrogen-containing basic group attached to at least one end of the oligopeptide; and (b) two or more heterocyclic monomers, at least one of which is substituted in the heterocyclic part by a branched, cyclic or part cyclic C3-5 alkyl group, or a pharmaceutically acceptable salt or solvate thereof; which compound, salt or solvate binds to the minor groove of DNA.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: April 20, 2010
    Assignee: University of Strathclyde
    Inventors: Abedawn Khalaf, Roger Waigh, Colin Suckling
  • Publication number: 20100051928
    Abstract: An organic electroluminescence device includes: a pair of electrodes; and at least one organic layer including a light emitting layer, the light emitting layer being provided between the pair of electrodes, wherein at least one layer of the at least one organic layer contains a compound represented by formula (1): wherein each of Z11 and Z12 independently represents an aromatic heterocyclic ring or an aromatic hydrocarbon ring; R11 represents a hydrogen atom or a substituent, provided that a plurality of R11s are the same or different; m represents an integer of 1 or more; and L1 represents a single bond or an m-valent linking group and is linked to any one of C atoms in R11, Z11 and Z12, provided that when m is 1, L1 does not exist.
    Type: Application
    Filed: September 4, 2009
    Publication date: March 4, 2010
    Applicant: FUJIFILM CORPORATION
    Inventor: Eiji FUKUZAKI
  • Publication number: 20090082576
    Abstract: A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting group, with (ii) a metal salt under basic conditions to produce the metalloporphyrin. Products produced by such methods and intermediates useful for carrying out such methods are also described.
    Type: Application
    Filed: February 11, 2008
    Publication date: March 26, 2009
    Applicant: North Carolina State University
    Inventors: Jonathan S. Lindsey, Dilek Dogutan Kiper
  • Publication number: 20080177073
    Abstract: The present teachings provide compounds of formulae I and II: where Q, Ra, R1, W, and n are as defined herein. The present teachings also provide methods of preparing compounds of formulae I and II, including methods of preparing compounds of formula II from compounds of formula I. The compounds disclosed herein can be used to prepare semiconductor materials and related composites and electronic devices.
    Type: Application
    Filed: January 7, 2008
    Publication date: July 24, 2008
    Inventors: Antonio Facchetti, Tobin J. Marks, He Yan
  • Patent number: 6576780
    Abstract: The current invention discloses hydroxyamidino derivatives useful as nitric oxide synthase inhibitors.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: June 10, 2003
    Assignee: GD Searle & Company
    Inventors: Rolando E. Gapud, Timothy J. Hagen, E. Ann Hallinan, Donald W. Hansen, Jr., Barnett S. Pitzele, Suzanne S. Metz, R. Keith Webber, Foe S. Tjoeng, Robert E. Manning, Mihaly V. Toth
  • Publication number: 20030087948
    Abstract: Compounds of the general formula I 1
    Type: Application
    Filed: October 18, 2002
    Publication date: May 8, 2003
    Inventors: Hakan Wikstrom, Durk Dijkstra, Bastiaan Johan Venhuis
  • Patent number: 6124465
    Abstract: Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. ##STR1## In the formula (I), the following substituents are among the preferred: Ar represents a substituted or condensed phenyl radical or a polycyclic or heterocyclic aromatic radical, R represents a radical of general formula --(CH.sub.2).sub.m --X.sub.1 --(CH.sub.2).sub.n --Z in which X.sub.1 =single bond, O, S; m=0, 1; n=0, 1, 2; it being possible for the CH.sub.2 radicals to be substituted; Z represents carboxyl, COOR.sub.6 (R.sub.6 =alkyl), CON(R.sub.7)(R.sub.8) (R.sub.7 =hydrogen or alkyl and R.sub.8 =hydrogen, hydroxyl, arylsulphonyl, heterocyclyl, optionally substituted amino, optionally substituted alkyloxy or optionally substituted alkyl), PO(OR.sub.9).sub.2 (R.sub.9 =hydrogen or alkyl), an --NH--CO--T (T=hydrogen or optionally substituted alkyl) radical, or else--a ##STR2## radical, R.sub.1 and R.sub.
    Type: Grant
    Filed: July 2, 1999
    Date of Patent: September 26, 2000
    Assignee: Rhone-Poulenc S.A.
    Inventors: Jean-Dominique Bourzat, Alain Commer.cedilla.on, Norbert Dereu, Patrick Mailliet, Fabienne Sounigo-Thompson, Jean-Paul Martin, Marc Capet, Michel Cheve
  • Patent number: 6107345
    Abstract: A compound of formula (I): ##STR1## wherein: Z.sub.1, Z.sub.2, Z.sub.3, Z.sub.4, which may be identical or different, represent a group as defined in the description,X represents oxygen, S(O).sub.p, --(CH.sub.2).sub.n -- or --CH.sub.2 --Y--CH.sub.2 -- wherein p, n and Y are as defined in the description,A represents ##STR2## wherein m, R.sub.1, R.sub.2 and G are as defined in the description, their isomers and addition salts thereof with a pharmaceutically-acceptable acid, and medicinal products containing the same are useful in the treatment of diseases like depression, panic attacks, obsessive compulsive disorders, phobias, impulsive disorders, drug abuse or anxiety.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: August 22, 2000
    Assignee: Adir et Compagnie
    Inventors: Jean-Louis Peglion, Aimee Dessinges, Jean-Christophe Harmange, Mark Millan, Adrian Newman-Tancredi, Mauricette Brocco
  • Patent number: 5968933
    Abstract: The invention relates to novel bis-benzimidazole compounds which have the ability to bind to the minor groove of DNA and to alkylate DNA, to methods of preparing the compounds, and the use of the compounds in the treatement of neoplastic disease.
    Type: Grant
    Filed: February 19, 1997
    Date of Patent: October 19, 1999
    Assignees: Auckland Division Cancer Society of New Zealand Inc., Circadian Pharmaceuticals (Australia) Pty. Ltd.
    Inventors: William A. Denny, Jeffrey B. Smaill
  • Patent number: 5457119
    Abstract: New hapalindole-type alkaloids called A89271 A-F and I are antifungal and antitumor agents. Methods for preparing them and for preparing hapalindoles G and H by culturing the blue-green alga Fischerella ambigua ATCC 55210 are provided. Methods for preparing A89271 factors B and F by culturing the blue-green alga Hapalosiphon hibernicus ATCC 55225 and a biologically pure culture of this alga are also provided. Further provided are methods and compositions for the inhibition of fungal growth and the treatment of susceptible neoplasms.
    Type: Grant
    Filed: July 8, 1994
    Date of Patent: October 10, 1995
    Assignee: Eli Lilly and Company
    Inventors: Roseanne Bonjouklian, Richard E. Moore, Gregory M. L. Patterson, Tim A. Smitka
  • Patent number: 5411960
    Abstract: Substituted pyrroloanthracenes are prepared by reacting either furanoanthracenes or N-unsubstituted pyrroloanthracenes with appropriately substituted alkylamines. The compounds can be employed as active ingredients in medicaments, in particular as immunomodulators.
    Type: Grant
    Filed: December 9, 1993
    Date of Patent: May 2, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Eckhard Schwenner, Gaetan Ladouceur, Hans-Joachim Kabbe, Thomas M. Aune
  • Patent number: 5302589
    Abstract: The present invention relates to certain substituted 17 .beta.-substituted carbonyl-6-azaandrost-4-en-3-ones of formula (I): ##STR1## wherein R.sup.1 and R.sup.2 arei) independently hydrogen or lower alkyl and the bond between the carbons bearing R.sup.1 and R.sup.2 is a single or a double bond, orii) taken together are a --CH.sub.2 -- group to form a cyclopropane ring, and the bond between the carbons bearing R.sup.1 and R.sup.2 is a single bond;X is ##STR2## wherein R.sup.5, R.sup.6, R.sup.7 and R.sup.8 are independently hydrogen or lower alkyl,p and q are independently either 0 or 1;R.sup.3 is lower alkyl, lower alkenyl, lower cycloalkyl, lower alkoxy, thiopyridyl, adamantyl, --NR.sup.9 R.sup.10 or --Ar--NR.sup.9 R.sup.10whereinR.sup.9 and R.sup.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: April 12, 1994
    Assignee: Glaxo, Inc.
    Inventors: Stephen V. Frye, David Middlemiss, Francis G. Fang
  • Patent number: 5264538
    Abstract: Cyclic poly(aryl ether) oligomers and mixtures thereof, and methods for the preparation thereof in a highly dilute reaction medium under reaction conditions favorable for ring closure at low degrees of polymerization. These oligomers are represented by the general formula ##STR1## where each Y is divalent oxygen or divalent sulfur, each Ar is an aromatic diradical which comprises one or more C.sub.6 to C.sub.20 arylene groups and has at least one electron withdrawing group attached to an aromatic ring, and n is an integer from 1 to about 20 with the proviso that for integer values of n equal to 1 or 2 all linkages between independent aromatic rings comprise at least one atom.
    Type: Grant
    Filed: June 27, 1990
    Date of Patent: November 23, 1993
    Assignee: The Dow Chemical Company
    Inventors: Michael J. Mullins, Edmund P. Woo, Kimberly E. Balon, Daniel J. Murray, Cheng-Cheng C. Chen
  • Patent number: 5137908
    Abstract: 4-Azahexacyclo (5.4.1.0.sup.2,6 .0.sup.3,10 .0.sup.5,9 .0.sup.8,11) dodecane compounds of the formula ##STR1## wherein R, A and B each is hydrogen; a linear or branched alkyl group having one to twelve carbon atoms and optionally including a hydroxyl or halogen substituent; or a phenyl group alone or optionally substituted with a linear or branched alkyl group having one to twelve carbons, which group optionally includes a hydroxyl or halogen substituent; and X is a hydroxyl or --NR.sub.2 group where R is as stated above; or an acid addition salt of such compound. These compounds are useful in pharmaceutical compositions wherein the compound is included in an amount effective to be used as a calcium antogonist, a cardiac agent or an anti-hypertensive agent.
    Type: Grant
    Filed: December 13, 1990
    Date of Patent: August 11, 1992
    Assignee: Noristan Holdings Limited
    Inventors: Theunis G. Fourie, Friedrich O. Snyckers
  • Patent number: 4988710
    Abstract: A compound and method are disclosed for reducing neurotoxic effects (such as seizures and brain damage) caused by cholinergic agents such as soman (a nerve gas) and pilocarpine (a convulsant drug used to study the mechanisms of epilepsy). Effective treatment can be provided by administering an aryl-cycloalkylalkanolamine substance having the general formula: ##STR1## The compoudns procyclidine, biperiden, and trihexyphenidyl fall within this class of compounds. Although not previously recognized to be effective against soman or other cholinergic neurotoxins, all three representative compounds have been discovered to be highly effective against all cholinergic neurotoxins tested to data, even when administered after actual seizures begin.
    Type: Grant
    Filed: August 25, 1989
    Date of Patent: January 29, 1991
    Assignee: Washington University
    Inventor: John W. Olney
  • Patent number: 4960860
    Abstract: The present invention provides an improved epoxy resin composition comprising an epoxy resin and a novel imide compound represented by the formula ##STR1## wherein X represents an --NH.sub.2 group and/or --OH group, Ar.sub.1 and Ar.sub.2 independently represent an aromatic residue, R.sub.1 represents a hydrogen atom or an alkyl group having from 1 to 10 carbon atoms, R.sub.2 represent a hydrogen atom, an alkyl or alkoxy group having from 1 to 20 carbon atoms or hydroxyl group, and each of m and n represents a number of from 0 to 30.
    Type: Grant
    Filed: May 31, 1989
    Date of Patent: October 2, 1990
    Assignee: Sumitomo Chemical Co., Ltd.
    Inventors: Yasuhisa Saito, Kunimasa Kamio, Mitsuhiro Shibata, Katsuya Watanabe, Yutaka Shiomi, Youichi Ueda
  • Patent number: 4939012
    Abstract: Naphtholactam dyes of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, n, p, Z.sup.1, Z.sup.2 and the rings A, B, C and D each have the meanings stated in the description, and an optical recording medium which contains one or more naphtholactam dyes and may contain a base.
    Type: Grant
    Filed: August 21, 1989
    Date of Patent: July 3, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Matthias Dust, Peter Neumann, Ernst Schefczik, Heidi Benthack-Thoms, Helmut Barzynski, Klaus-Dieter Schomann, Harald Kupplemaier, Eberhard Koester
  • Patent number: 4939241
    Abstract: The invention relates to compounds of antitumor activity of the formula: ##STR1## ps in which R.sup.1 is hydrogen, lower allkyl, halo(lower)alkyl or aryl,R.sup.2 is hydrogen, hydroxy or protected hydroxy,R.sup.3 is hydrogen,R.sup.4 is aminocarboxy(lower)alkyl, protected amino(lower)alkyl or protected aminocarboxy(lower)alkyl, andR.sup.5 is hydrogen or lower alkyl, or its pharmaceutical acceptable salt.
    Type: Grant
    Filed: March 25, 1988
    Date of Patent: July 3, 1990
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Masakuni Okuhara, Toshio Goto, Masami Ezaki, Miho Tanaka, Shigehiro Takase, Hidenori Nakajima, Hideo Hirai, Akira Katayama
  • Patent number: 4876356
    Abstract: Naphtholactam dyes of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, n, p, Z.sup.1, Z.sup.2 and the rings A, B, C and D each have the meanings stated in the description, and an optical recording medium which contains one or more naphtholactam dyes and may contain a base.
    Type: Grant
    Filed: March 12, 1987
    Date of Patent: October 24, 1989
    Assignee: BASF Aktiengesellschaft
    Inventors: Matthias Dust, Peter Neumann, Ernst Schefczik, Heidi Benthack-Thoms, Helmut Barzynski, Klaus-Dieter Schomann, Harald Kuppelmaier, Eberhard Koester
  • Patent number: 4830951
    Abstract: Naphtholactamsquaric acid dyes of the formula ##STR1## where R.sup.1 and R.sup.2 independently of one another are each unsubstituted or substituted C.sub.3 -C.sub.22 -alkyl, in which the alkyl chain may be interrupted by oxygen atoms, or are each unsubstituted or substituted C.sub.1 -C.sub.4 -aralkyl, unsubstituted or substituted C.sub.5 -C.sub.7 -cycloalkyl or unsubsituted or substituted phenyl, and the rings A, B, C and D are unsubstituted or substituted and/or benzofused, and optical recording materials consisting of a base and a layer which is sensitive to laser light and is composed of a thermoplastic or crosslinked polymer and one or more dyes (I).Because of the high light absorption of (I), the recording materials are very sensitive to light from the GaAlAs semiconductor laser. An excellent signal-to-noise ratio is obtained on reading the recordings.
    Type: Grant
    Filed: September 4, 1987
    Date of Patent: May 16, 1989
    Assignee: BASF Aktiengesellschaft
    Inventors: Matthias Dust, Peter Neumann, Peter Hauser, Gerhard Wagenblast, Heidi Benthack-Thoms, Helmut Barzynski, Klaus D. Schomann, Harald Kuppelmaier
  • Patent number: 4820846
    Abstract: Compounds which are useful as sensitizers of photoconductors, having the general formula: ##STR1## in which: like symbols represent identical substituents,at least 4 of R.sup.1 to R.sup.9 represent hydrogen atoms and the remaining R.sup.1 to R.sup.9 pairs of groups independently represent:(i) hydrogen, an alkyl group having from 1 to 18 carbon atoms, a substituted alkyl group, or an aryl or substituted aryl group,(ii) a halogen atom, a cyano group, a carboxy or alkoxycarbonyl group, a hydroxy group, an alkoxy group, a nitro group or a sulfonic acid group, providing that not more than two such groups (ii) are present in each ring,(iii) an acylamino group, a secondary acylamino group or a tertiary amino group in which the pendant substituent groups on the nitrogen atom are alkyl, aryl or aralkyl, providing not more than two such groups (iii) may be present in each benzocarbazole ring, and(iv) any two groups R.sup.1 to R.sup.
    Type: Grant
    Filed: September 12, 1983
    Date of Patent: April 11, 1989
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: D. E. Brown, Kenneth Reynolds
  • Patent number: 4670461
    Abstract: New substituted, formaldehyde derived mitindomide and methods of preparing the same are disclosed. The novel compounds are water soluble and have anti-neoplastic activity. The formaldehyde derived mitindomide is prepared by reacting mitindomide with formaldehyde and further acetylating the derived hydroxymethyl compound. The amido compounds can be derived by reacting mitindomide in mannich fashion, i.e-formaldehyde and secondary amines.
    Type: Grant
    Filed: April 26, 1984
    Date of Patent: June 2, 1987
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Rudiger D. Haugwitz, Venkatachala L. Narayanan, Leon H. Zalkow, Howard M. Deutsch
  • Patent number: 4555563
    Abstract: Imide functional polyphenols are prepared by reacting an excess of a phenol with an unsaturated diimide which is prepared by reacting an unsaturated polycycloaliphatic dicarboxylic acid anhydride with a diamine.These materials are useful in the preparation of castings, coatings, laminates and the like.
    Type: Grant
    Filed: December 7, 1984
    Date of Patent: November 26, 1985
    Assignee: The Dow Chemical Company
    Inventors: Robert E. Hefner, Jr., Mary N. White
  • Patent number: 4465688
    Abstract: The invention concerns adducts of 1,8-dihydroxy-9-anthrone, of formula: ##STR1## in which: R.sub.1 and R.sub.2, taken together, form one of the following divalent residues: ##STR2## R.sub.3, R.sub.4, R'.sub.4, R.sub.5 and R'.sub.5 representing H, an alkyl group having 1-8 C with the exception of R.sub.5 =R'.sub.5 =CH.sub.3, a monohydroxyalkyl group with 2-8 C, possibly interrupted by one or more oxygens, a cycloalkyl group having 4-6 C, a phenyl group, or a benzyl group.Utilization of the compounds (I) in human or veterinary medicine, in particular in the treatment of psoriasis and or warts, and in cosmetics.
    Type: Grant
    Filed: June 29, 1982
    Date of Patent: August 14, 1984
    Assignee: Groupement d'Interet Economique Centre International de Recherches Dermatologiques C.I.R.D.
    Inventors: Braham Shroot, Jean Maignan, Gerard Lang
  • Patent number: 4417057
    Abstract: Compounds of the formulae I or II ##STR1## and processes for their preparation are described. In the above formulae, Z is a tetravalent aliphatic radical, which can be interrupted by hetero-atoms, or a substituted or unsubstituted tetravalent cycloaliphatic radical, which can contain hetero-atoms and/or can be fused to a benzene ring, A is --C(R.sup.4).dbd.C(R.sup.5)(R.sup.6) or --C.tbd.C--R.sup.5, especially --CH.dbd.CH.sub.2, R.sup.1 and R.sup.2 independenty of one another are H, methyl, phenyl, --CN or Cl, or together are trimethylene, tetramethylene, ##STR2## R.sup.3 is a direct bond, C.sub.1-8 alkylene, cyclohexylene, phenylene or --CH.sub.2 -phenylene with the --CH.sub.2 group bonded to the N atom, R.sup.4 and R.sup.6 independently of one another are H, methyl or ethyl and R.sup.5 is H or C.sub.1-9 alkyl. The compunds of the formula I and II are valuable intermediates for the preparation of silicon-modified adhesion promoters.
    Type: Grant
    Filed: June 26, 1981
    Date of Patent: November 22, 1983
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Lohmann, Martin Roth, Marcus Baumann
  • Patent number: 4339383
    Abstract: The invention relates to alkanolamido-.beta.-carboxylic acid esters of the formula I ##STR1## A full definition of the above formula will be found in claim 1 of the specification. These compounds are useful stabilizers for chlorinated thermoplastics.
    Type: Grant
    Filed: July 2, 1980
    Date of Patent: July 13, 1982
    Assignee: Ciba-Geigy Corporation
    Inventors: Wolfgang Wehner, Klaus-Peter Michaelis, Rainer Schneider