Abstract: Polyol ether derivatives, a method for producing the polyol ether derivatives, and a working fluid composition for a refrigerating machine containing a hydrofluorocarbon and a refrigeration oil containing the polyol ether derivatives as a base oil.

Abstract: The use of compounds of the following formula I: ##STR1## for treating psoriasis is disclosed.

Abstract: The invention relates to chiral compounds of the general formulaA--Y--(M--Y).sub.n --B--(Y--M).sub.n --Y--AwhereB is a radical of the formula ##STR1## and where the radicals A independently of one another are C.sub.1 - to C.sub.20 -alkyl which may be substituted by fluorine, chlorine, bromine or cyano and may be interrupted by O, S, NH, NCH.sub.3, COO or OCO,X are carbon or boron,Y independently of one another are a chemical bond, O, S, NH, N(CH.sub.3), COO or OCO andM independently of one another are a mesogenic group andn independently of one another are 0 or 1 with the proviso that one n is other than 0.The compounds according to the invention are suitable as dopes in liquid-crystalline media.

Abstract: Disclosed are certain 1,3-2,4-di(substituted arylidene)-and 1,3-2,4-di(substituted heteroarylidene)-D-sorbitols which are useful as clarifying and nucleating additives for crystalline and semi-crystalline polyolefin compositions. Also disclosed are such poly(C.sub.1 -C.sub.8 alpha olefin) compositions containing them.

Abstract: 1,2,4-trioxane derivatives of formula: ##STR1## (wherein each of the subscripts m and n is equal to 0 or 1;the symbol Z represents an epoxide oxygen atom at the 5,6 or 6,7 positions, or a pair of electrons forming a double bond at the 5,6 or 6,7 positions;each of the symbols Ar.sup.1 and Ar.sup.2, being the same or different represents an aromatic group which optionally substituted;each of the symbols AR.sup.1 and R.sup.2, being the same or different, represents a linear or branched alkyl group, which is optionally substituted, or R.sup.1 and R.sup.

Abstract: Cytotoxic metabolites are isolated by extraction and chromatography from a marine sponge of the same species as that deposited in the Zoological Museum of the University of Amsterdam under reg. no. ZMA POR. 10883. The isolated compounds belong to the genus of compounds having the structure: ##STR1## wherein R is C.sub.6 -C.sub.12 alkyl or C.sub.6 -C.sub.12 alkenyl having 1 or 2 double bonds, which may be interrupted with one or more imino groups and which may be substituted with one or more substituents selected from the group consisting of amino, carboxyl, hydroxy, imino and oxo.

Abstract: A series of novel alkoxypyridin-4-yl and alkoxypyrimidin-4-yl derivatives of indol-3-ylalkylpiperazines of Formula I are intended to be useful agents ##STR1## for alleviation of vascular headache on the basis of their potent affinity and agonist activity at 5-HT1D binding sites.

Abstract: Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

Abstract: A physical property-improving reagent which comprises an alkenoylcarbamate compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group, X is an oxygen atom (--O--), a sulfur atom (--S--) or a substituted or unsubstituted imino group (--NR'--), R' being a hydrogen atom or a lower alkyl group, and Y is the residue of an active hydrogen atom-containing compound excluding --X--H therefrom dissolved in an organic solvent having a solubility parameter of not less than 8, which can impart excellent physical properties to a polymer produced with the same.

Abstract: A process for incorporating a clarifying agent into a semi-crystalline polyolefin resin is provided whereby a clarifying agent selected from compounds having the formula: ##STR1## wherein p is 0 or 1, m and n are independently 0-3, and R is, at each occurrence, independently selected from C.sub.1-8 alkyl, C.sub.1-4 alkoxy, hydroxy, halogen, C.sub.1-6 alkylthio, C.sub.1-6 alkylsulfoxy and a 4 or 5 membered alkyl group forming a carbocyclic ring with adjacent carbon atoms of the unsaturated parent ring, and wherein the clarifying agent is in the form of a powder characterized by a d.sub.97 of 30 microns or less, and a mean particle size of 15 microns or less, is blended with the polyolefin resin, at a temperature above 170.degree. C. until the clarifying agent is dissolved in the molten resin.

Abstract: Processes for eliminating the diethanolamine present in triethanolamine and the preparation of triethanolamine or compositions containing triethanolamine substantially free from diethanolamine in which the triethanolamine containing diethanolamine is treated with glyoxal in a molar ratio of glyoxal to diethanolamine greater than or equal to 1, then if desired the triethanolamine obtained or the composition containing it is isolated, and their use.

Abstract: A process for stabilizing dibenzylidenesorbitols comprising incorporating 0.05-20 pts. wt. sorbic acid and/or potassium sorbate in 100 pts. wt. dibenzylidenesorbitol represented by the following formula, ##STR1## and a stabilized dibenzylidenesorbitol composition formed thereby. The storage stability of dibenzylidenesorbitols is thus greatly improved.

Abstract: Bis(3,4-dialkylbenzylidene) sorbitol acetals are provided for the formula: ##STR1## in which R.sub.1 and R.sub.2 are independently selected from lower alkyl groups containing 1-4 carbon atoms.

Abstract: Disclosed is a process for preparing a diacetal compound such as a dibenzylidene sorbitol, comprising the steps of (i) condensing an aldehyde compound and a polyhydric alcohol in the presence of an acid catalyst and when required a lower alcohol in a hydrophobic organic solvent to give a reaction mixture containing a diacetal compound, (ii) neutralizing the reaction mixture, (iii) washing the mixture with water, (iv) removing the solvent from the mixture thus washed, and (v) drying the residual mass; the process being characterized in that an amine such as, for example, di(C.sub.10 -C.sub.26 alkyl or alkenyl)amine substituted on the nitrogen atom with a C.sub.1 -C.sub.4 alkyl group or with a group of the formula --C.sub.2 H.sub.4 O).sub.q H wherein q is an integer of 1 to 4, or a (C.sub.14 -C.sub.22 alkyl or alkenyl)amine sustituted on the nitrogen atom with one or two groups of the formula --C.sub.2 H.sub.4 O).sub.

Abstract: A process for preparing dibenzylidene-D-sorbitol compounds, particularly meta substituted halogenated derivatives, by reacting D-sorbitol with an aromatic aldehyde, particularly those substituted at the 3 position with a halogen, in the presence of an acid catalyst, and a C.sub.1 -C.sub.3 aliphatic alcohol reaction medium. The resulting product is purified by subsequent washings with a C.sub.1 -C.sub.3 aliphatic alcohol. Higher yields of the product, shorter reaction times, and simplified removal of impurities may be realized using this invention.

Abstract: Bis(3,4-dialkylbenzylidene) sorbitol acetals are provided for the formula: ##STR1## in which R.sub.1 and R.sub.2 are independently selected from lower alkyl groups containing 1-4 carbon atoms, or together form a carbocyclic ring containing up to 5 carbon atoms.

Abstract: The invention is concerned with diacetals resulting of the dehyrocondensation of an alditol comprising 5 or 6 carbon atoms and a benzoic aldehyde such as in particular DBS, BEBS, BMBS or DBX, featuring a purity of at least 95% and being free of organic solvent traces, and a process for preparing the same in aqueous medium, in the presence of an acid catalyst, according to which acetalization is carried out by mixing the reactants under stirring, the reaction mixture is then neutralized by a base, then the solid phase is separated from the liquid phase and washed with warm water, wherein: the initial molar ratio of the benzoic aldehyde to the alditol is lower than 2/1, the acid catalyst is an arylsulfonic acid, the initial molar ratio of the arylsulfonic acid to the benzoic aldehyde is higher than 0.6, and the reaction temperature is lower than about 45.degree. C.Application specially to the clarification and stabilization of polyolefins.

Abstract: A dibenzylidenesorbitol derivative having at least one nuclear substituent selected from an ester group represented by --COOR.sup.1 and an amido group represented by --CONR.sup.2 R.sup.3, wherein R.sup.1 represents a hydrocarbon group having 1 to 20 carbon atoms, and R.sup.2 and R.sup.3 are identical or different and each independently represents a hydrogen atom, an alkyl group, an aryl group or an aralkyl group.

Abstract: Unsymmetric biaryl compounds are prepared by coupling two different halogenoaromatics by reaction with a metal and carrying out the reaction in the presence of catalytic amounts of a nickel compound, a promoter and a phosphorus-containing ligand.

Abstract: Disclosed is a process for batchwise production of a 1,3:2,4-dibenzylidene-sorbitol or xylitor compound comprising subjecting a sorbitol or xylitol and a benzaldehyde compound to a condensation reaction in a reactor by feeding a homogeneous solution or suspension formed from (a) sorbitol or xylitor, (b) an aldehyde compound, (c) a lower alcohol, and if necessary (d) an acid catalyst, to the reactor, together with a hydrophobic organic solvent, continuously or intermittently while adjusting the rate of feeding of said homogeneous solution or suspension such that sorbitol or xylitol and the benzaldehyde compound are fed to the reaction system in a total amount per hour of about 0.1 to about 2 parts by weight per part by weight of the 1,3:2,4-dibenzylidene compound as found in the reaction system.

Abstract: Mycalamide compounds are derived from marine sponges of the genus Mycale or prepared by synthetic methods. These compounds and pharmaceutical compositions containing them as active ingredients are useful as antitumor and antiviral agents.

Abstract: Polyolefin compositions having high clarity and resistance to oxidative degradation are obtained with new dibenzylidene sorbitol additives having a sulfur-containing substituent on at least one of the benzylidene rings. Preferred additives are thioethers.

Abstract: This invention relates to novel compositions which are useful as antitumor, antiviral and antifungal compositions, a process of producing the compositions and a method for inhibiting tumors, viruses and fungi utilizing the composition. More particularly, the novel compositions are derived from marine sponge Theonella sp.

Abstract: This invention relates to novel compositions which are useful as antitumor, antiviral and antifungal compositions, a process of producing the compositions and a method for inhibiting tumors, viruses and fungi utilizing the composition. More particularly, the novel compositions are derived from marine sponge Theonella sp.

Abstract: A process for the preparation of a dimeric aromatic acyl cyanide of the formula ##STR1## in which Ar is optionally substituted phenyl, naphthyl or hetaryl,comprising reaction an acyl halide of the formulaAr--CO--Halin whichHal is fluorine, chlorine or bromine, with an alkali metal cyanide in a two-phase system comprising water and a water-immiscible or only sparingly water-miscible aliphatic ketone, and in the presence of a phase-transfer catalyst. The products are known intermediates for pesticides.

Abstract: A method is provided for producing a di-acetal of sorbitol and an aromatic aldehyde wherein an aqueous solution containing a catalytic amount of a mineral acid and sorbitol is formed. Thereafter, an effective amount of an aromatic aldehyde such as benzaldehyde is incrementally admixed into the homogeneous aqueous admixture containing the sorbitol at a rate sufficient to allow a substantially spontaneous reaction to occur between the D-sorbitol and aromatic aldehyde; thus, forming an aqueous slurry containing crude di-acetal, e.g., dibenzylidene sorbitol. The amount of aromatic aldehyde employed is that amount sufficient to provide a molar ratio of D-sorbitol to aromatic aldehyde of from about 1:0.75 to about 1:1.75. Thereafter, the aqueous slurry is neutralized, and crude di-acetal is removed from the liquid phase and washed with water to remove mono-acetal impurities, e.g., monobenzylidene sorbitol.