Unsaturated Patents (Class 562/598)
-
Patent number: 11867324Abstract: Hoses include an inner tube, a reinforcement layer disposed outwardly from the inner tube, and a cover layer disposed outwardly from the reinforcement layer, where the cover layer and/or the inner tube includes a cured composition having a sustainable content and formed from a mixture including EPDM/EPR sustainable polymer and a sulfur or peroxide based curing system. In some cases, the EPDM/EPR sustainable polymer has ethylene monomer derived from one or more renewable sources, such as, ethylene monomer derived from sugar cane. The mixture may further include one or more of recovered carbon black and sustainable oils from renewable sources. The hose embodiments may also include the reinforcement layer formed of fibers from sustainable material. The hose may contain the sustainable content in an amount of up to 75% by weight based upon total hose weight, or even greater than 25% by weight based upon total hose weight.Type: GrantFiled: November 2, 2021Date of Patent: January 9, 2024Assignee: ContiTech USA, Inc.Inventors: Lance Miller, Jeffrey T. Epperson, Jenny Zhaoxia Yu, Mathew Augustine, Jeffrey P. Dotson
-
Patent number: 11807602Abstract: The present invention relates to a process for preparing a 3-isopropenyl-6-heptenal compound of the following formula (2): wherein R1 represents a hydrogen atom or a methyl group, the process comprising: subjecting a 3-isopropenyl-6-heptenoate ester compound of the following formula (1): wherein R1 is as defined above, and R2 represents a monovalent hydrocarbon group having 1 to 10 carbon atoms, to a reduction reaction with a reducing agent to form the 3-isopropenyl-6-heptenal compound (2).Type: GrantFiled: December 7, 2021Date of Patent: November 7, 2023Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Akihiro Baba, Takeshi Kinsho, Naoki Ishibashi, Yusuke Nagae
-
Patent number: 11779910Abstract: Disclosed herein are methods for preparing isotopically modified polyunsaturated lipids containing 1,4-diene systems involving selective isotopic modification of one or more bis-allylic positions of the polyunsaturated lipids in the presence of a transition metal catalyst.Type: GrantFiled: February 19, 2021Date of Patent: October 10, 2023Assignee: BioJiva LLCInventors: Dragoslav Vidovic, Mikhail S. Shchepinov
-
Patent number: 11773215Abstract: Provided is a method of producing a film by cryogenically grinding polypropiolactone to form a powder, and extruding the powder to form the film. Provided herein are also polypropiolactone films having certain biocontent and compostability, as well as certain mechanical and physical properties. Such films may also be suitable for use as packaging materials.Type: GrantFiled: April 1, 2019Date of Patent: October 3, 2023Assignee: Novomer, Inc.Inventor: Utpal Mahendra Vakil
-
Patent number: 11420919Abstract: The present invention provide for preparing a formylalkenyl alkoxymethyl ether compound of the following general formula (2): R3CH2OCH2O(CH2)aCH?CHCHO (2), wherein R3 represents a hydrogen atom, an n-alkyl group having 1 to 9 carbon atoms, or a phenyl group; and “a” represents an integer of 1 to 10, the process comprising: hydrolyzing a dialkoxyalkenyl alkoxymethyl ether compound of the following general formula (1): R3CH2OCH2O(CH2)aCH?CHCH(OR1)(OR2) (1), wherein R1 and R2 represent, independently of each other, a monovalent hydrocarbon group having 1 to 15 carbon atoms, or R1 and R2 may form together a divalent hydrocarbon group, R1-R2, having 2 to 10 carbon atoms; and R3 and “a” are as defined above, in the presence of an acid while removing an alcohol compound thus generated to form the formylalkenyl alkoxymethyl ether compound (2).Type: GrantFiled: March 23, 2021Date of Patent: August 23, 2022Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Yuki Miyake, Takeshi Kinsho, Miyoshi Yamashita
-
Patent number: 11089805Abstract: The present invention provides a mucosal immunomodulator comprising, as an active ingredient, at least one selected from the group consisting of compounds represented by the following formula (1), compounds represented by the following formula (2) and compounds represented by the following formula (3), and salts thereof.Type: GrantFiled: October 12, 2017Date of Patent: August 17, 2021Assignees: Yamada Bee Company, Inc., National University Corporation Kumamoto UniversityInventors: Shogo Misumi, Tomoki Ikuta, Tomoki Tatefuji, Hiroko Tani, Hiroshi Inooka
-
Patent number: 10364213Abstract: The present invention provides a method for producing ?-hydroxyisobutyric acid amide by hydration of acetone cyanohydrin under the presence of a catalyst composed mainly of manganese oxide using a reactor in which at least two reaction regions are connected in series, the method being characterized by comprising: a step (B) of cyclically supplying at least a portion of a reaction liquid withdrawn from at least one reaction region to a first reaction region (I) in the reactor; and a step (b1) of further cyclically supplying at least a portion of the reaction liquid withdrawn from at least one reaction region to at least one reaction region other than the first reaction region. The method is also characterized in that an oxidizing agent is supplied to at least one reaction region in the reactor.Type: GrantFiled: April 25, 2017Date of Patent: July 30, 2019Assignee: MITSUBISHI GAS CHEMICAL COMPANY, INC.Inventors: Atsushi Kakimi, Takako Uchiyama, Hideho Matsuda, Masaki Takemoto, Katsumi Higuchi
-
Patent number: 10035747Abstract: The present invention provides a method for allowing a used inert material that has been subjected to a reaction once, which is disposed of in the background art, to be used again as well as a brand-new one. A method of recovering an inert material of the present invention is characterized by in the fixed-bed reactor, the inert material is loaded in an inert material layer provided between a first-stage catalyst layer and a second-stage catalyst layer, the first-stage catalyst layer is loaded with a first-stage catalyst for producing acrolein from propylene, and the second-stage catalyst layer is loaded with a second-stage catalyst for producing acrylic acid from acrolein, the method comprising the steps of: extracting the inert material from the fixed-bed reactor; washing the extracted inert material; and screening the washed inert material.Type: GrantFiled: July 30, 2015Date of Patent: July 31, 2018Assignee: NIPPON SHOKUBAI CO., LTD.Inventors: Yasuhiro Mimura, Fumio Munechika, Hisao Kakuta, Motoki Hisanaga, Seiichi Hara
-
Patent number: 9771314Abstract: The invention relates to a process for preparing acrylic acid from formaldehyde and acetic acid, comprising (i) providing a gaseous stream S1 comprising formaldehyde, acetic acid and acrylic acid, where the molar ratio of acrylic acid to the sum total of formaldehyde and acetic acid in stream S1 is in the range from 0.005:1 to 0.3:1; (ii) contacting stream S1 with an aldol condensation catalyst in a reaction zone to obtain a gaseous stream S2 comprising acrylic acid.Type: GrantFiled: November 10, 2016Date of Patent: September 26, 2017Assignee: BASF SEInventors: Marco Hartmann, Lukas Schulz, Nicolai Tonio Woerz, Yong Liu, Till Christian Brueggemann, Michael Lejkowski, Johannes Lieberknecht
-
Patent number: 9290430Abstract: Technical grade acrylic acid derived from renewable resources utilizing a homogeneous nickel catalyst system by a process including reacting lactide with acetic acid to form 2-acetoxypropionic acid in the presence of a homogeneous nickel catalyst, pyrolyzing, with or without a catalyst, the 2-acetoxypropionic acid to acrylic acid and acetic acid, condensing and collecting the pyrolysis products in the presence of polymerization inhibitor(s) and purifying the acrylic acid by distillation in the presence of polymerization inhibitor(s). Acrylic acid and methyl acrylate are produced from methyl 2-acetoxypropionate which comes from fermentation derived lactic acid. The disclosed process will produce a “green” (i.e. renewable resources derived) acrylic acid and methyl acrylate ester.Type: GrantFiled: April 20, 2015Date of Patent: March 22, 2016Assignee: SGA Polymers, LLCInventors: Olan S. Fruchey, Thomas A. Malisezewski, John E. Sawyer
-
Patent number: 9193661Abstract: In one embodiment, the invention is to a process for producing an acrylate product. The process comprises the step of providing a crude product stream comprising the acrylate product and an alkylenating agent. The process further comprises the step of separating at least a portion of the crude product stream to form an alkylenating agent stream and an intermediate product stream. The alkylenating agent stream comprises at least 1 wt % alkylenating agent and the intermediate product stream comprises acrylate product.Type: GrantFiled: January 9, 2014Date of Patent: November 24, 2015Assignee: Celanese International CorporationInventors: Craig J. Peterson, Josefina T. Chapman, Ilias S. Kotsianis, Sean Mueller, Dick Nagaki, Tianshu Pan
-
Patent number: 9174913Abstract: A process for the production of methacrylic acid is described. The process comprises the base catalysed decarboxylation of at least one or a mixture of dicarboxylic acids selected from itaconic, citraconic or mesaconic acid. The decarboxylation is carried out in the range greater than 240 and up to 275° C. to provide high selectivity. The methacrylic acid product may be esterified to produce an ester. A method of preparing polymers or copolymers of methacrylic acid or methacrylic acid esters using the process is also described. Optionally, the process may be preceded with a decarboxylation and, if necessary, a dehydration step on a source of pre-acid such as citric acid or isocitric acid.Type: GrantFiled: November 18, 2011Date of Patent: November 3, 2015Assignee: Lucite International UK LimitedInventors: David William Johnson, Graham Ronald Eastham, Martyn Poliakoff, Thomas Andrew Huddle
-
Publication number: 20150133687Abstract: An ?,?-unsaturated aldehyde and/or an ?,?-unsaturated carboxylic acid are prepared by gas phase oxidation of alkene with molecular oxygen over a fixed catalyst bed comprising a bed of hollow cylindrical shaped catalyst bodies having a multimetal oxide active composition. The fixed catalyst bed comprises at least three successive reaction zones; the highest local temperature in the fixed catalyst bed does not occur in the reaction zone closest to the reactor outlet; the highest local temperature in the fixed catalyst bed does not occur in the reaction zone closest to the reactor inlet; and the value WT=(ED?ID)/2 in the reaction zone in which the highest local temperature in the fixed catalyst bed occurs is lower than in the other reaction zones, in which ED is the external diameter and ID is the internal diameter of the shaped catalyst body. The yield of the products of value is enhanced in this way.Type: ApplicationFiled: November 10, 2014Publication date: May 14, 2015Applicant: BASF SEInventors: Josef MACHT, Christian WALSDORFF, Cornelia Katharina DOBNER, Cathrin Alexandra WELKER-NIEUWOUDT, Ulrich HAMMON
-
Publication number: 20150126777Abstract: This invention relates to a process of preparing highly pure, non-yellowing (meth)acrylic acid necessary for high-tech applications requiring long-tem color stability in the presence of amines. Process for the preparation of highly pure, non-yellowing (meth)acrylic acid comprising the steps: f) Condensation of a (meth)acrylic acid-containing gas phase obtained via a gas phase oxidation process of a C4-compound to generate an aqueous (meth)acrylic acid solution g) Separation of the (meth)acrylic acid from the aqueous (meth)acrylic acid solution to obtain crude (meth)acrylic acid h) Rectification of the crude (meth)acrylic acid to obtain pure (meth)acrylic acid via a sidestream outlet of the rectification column i) Treatment of the pure (meth)acrylic acid generated in step c) with an ion exchange resin j) Distillation of the (meth)acrylic acid generated in step d).Type: ApplicationFiled: April 22, 2013Publication date: May 7, 2015Applicant: EVONIK INDUSTRIES AGInventors: Zhengfeng Zhang, Gerhard Koelbl, Lorenza Sartorelli, Horst Hiltner, Huisheng Wang, Mirko Michel
-
Publication number: 20150119541Abstract: A process for the production of methacrylic acid or esters thereof by the base catalysed decarboxylation of at least one dicarboxylic acid selected from itaconic, citraconic or mesaconic acid or mixtures thereof in an aqueous reaction medium is described. The decarboxylation is carried out at a temperature in the range from 200° C. and up to 239° C. The methacrylic acid is isolated from the aqueous reaction medium by a purification process which does not include introducing an organic solvent to the aqueous reaction medium for solvent extraction of the methacrylic acid into an organic phase. A method of preparing polymers or copolymers of methacrylic acid or methacrylic acid esters is also described.Type: ApplicationFiled: April 26, 2013Publication date: April 30, 2015Inventors: Graham Ronald Eastham, David William Johnson, Mark Waugh
-
Patent number: 9012686Abstract: Technical grade acrylic acid derived from renewable resources utilizing a homogeneous nickel catalyst system by a process including reacting lactide with acetic acid to form 2-acetoxypropionic acid in the presence of a homogeneous nickel catalyst, pyrolyzing, with or without a catalyst, the 2-acetoxypropionic acid to acrylic acid and acetic acid, condensing and collecting the pyrolysis products in the presence of polymerization inhibitor(s) and purfying the acrylic acid by distillation in the presence of polymerization inhibitor(s). Acrylic acid and methyl acrylate are produced from methyl 2-acetoxypropionate which comes from fermentation derived lactic acid. The disclosed process will produce a “green” (i.e. renewable resources derived) acrylic acid and methyl acrylate ester.Type: GrantFiled: September 6, 2011Date of Patent: April 21, 2015Inventors: Olan S. Fruchey, Thomas A. Malisezewski, John E. Sawyer
-
Publication number: 20150105586Abstract: Methods and systems are provided for converting methane in a feed stream to acetylene. The method includes processing the acetylene to form a stream having acrylic acid. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is be treated to convert acetylene to acrylic acid. The method according to certain aspects includes controlling the level of carbon monoxide to prevent undesired reactions in downstream processing units.Type: ApplicationFiled: December 18, 2014Publication date: April 16, 2015Inventors: Jeffery C. Bricker, John Q. Chen, Peter K. Coughlin
-
Publication number: 20150094438Abstract: A process for the production of methacrylic acid by the base catalysed decarboxylation of at least one dicarboxylic acid selected from itaconic, citraconic or mesaconic acid or mixtures thereof is described. The decarboxylation is carried out at a temperature in the range from 100 to 199° C. A method of preparing polymers or copolymers of methacrylic acid or methacrylic acid esters is also described.Type: ApplicationFiled: April 26, 2013Publication date: April 2, 2015Inventors: Graham Ronald Eastham, David William Johnson, Mark Waugh
-
Publication number: 20150080604Abstract: Described herein are methods for preparing acrylic acid from biobased starting materials, e.g., ethanol.Type: ApplicationFiled: September 16, 2014Publication date: March 19, 2015Inventor: JOSHUA LENSBOUER
-
Publication number: 20150065746Abstract: To address the problem of insufficient biodegradability of perfluorinated surfactants, the present invention provides biodegradable fluorosurfactants derived from olefins having —CHR, —CHRf, —CHF, and/or —CH2 groups, where R is an alkyl group and Rf is a perfluoro or fluroroalkyl group. Preferably, the —CHR, —CHRf, —CHF, and/or —CH2 groups are contained within partially fluorinated alkenes.Type: ApplicationFiled: August 14, 2014Publication date: March 5, 2015Inventors: Haridasan K. Nair, Yian Zhai, Andrew J. Poss, Rajiv R. Singh, David Nalewajek
-
Publication number: 20150057455Abstract: Methods and systems for producing high purity 3-hydroxypropionic acid (3-HP) from an aqueous medium, such as a fermentation broth, are described. Aqueous 3-HP solution can be purified by flash evaporation wherein the 3-HP is vaporized at an elevated temperature without conversion to acrylic acid. This process can be integrated with downstream processes for producing other chemical and consumer products.Type: ApplicationFiled: March 14, 2014Publication date: February 26, 2015Inventors: Cindy HOPPE, Sarah M. HOYT, Robert TENGLER, David DeCOSTER, Bradley HARKRADER, Patrick H. AU-YEUNG, Sanjib BISWAS, Pedro R. VARGAS, II, Raymond P. ROACH, Timothy Charles FRANK
-
Publication number: 20150045577Abstract: The present invention relates to a process for hydrolysis of acetone cyanohydrin (ACH) by means of sulphuric acid within the ACH sulpho process for preparation of methacrylic acid (MAA) or methyl methacrylate (MMA).Type: ApplicationFiled: March 6, 2013Publication date: February 12, 2015Applicant: Evonik Roehm GmbHInventors: Arndt Selbach, Lorenza Sartorelli, Andreas Perl, Joachim Deinken, Stefanie Sohnemann, Norbert Mnich, Matthias Groemping, Udo Gropp, Thomas Mertz
-
Publication number: 20150045583Abstract: A transesterification process produces a (meth)acrylate ester product from a mixture comprising an alkyl(meth)acrylate reactant, an alcohol reactant, a catalyst, and a polymerization inhibitor. The mixture is subjected to reaction conditions sufficient to produce a product (meth)acrylate and a product alcohol, which are different than the reactants.Type: ApplicationFiled: February 11, 2013Publication date: February 12, 2015Applicant: ROHM AND HAAS COMPANYInventors: David A. Flosser, Philippe P. Maillot, Nawal K. Sharma, Alejandro Ceron, Mingyu Ye
-
Publication number: 20150031911Abstract: The invention relates to a method for producing a shell catalyst that is suitable for producing vinyl acetate monomer (VAM). The invention further relates to a shell catalyst that is obtainable by the method according to the invention and to the use of the shell catalyst according to the invention for producing VAM.Type: ApplicationFiled: February 19, 2013Publication date: January 29, 2015Applicant: CLARIANT PRODUKTE (DEUTSCHLAND) GMBHInventors: Gerhard Mestl, Peter Scheck, Alfred Hagemeyer, Carolin Fischer, Roman Bobka
-
Patent number: 8933270Abstract: The present invention is generally drawn to novel isolated therapeutic agents, termed resolvins, generated from the interaction between a dietary omega-3 polyunsaturated fatty acid (PUFA) such as eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA), cyclooxygenase-II (COX-2) and an analgesic, such as aspirin (ASA). Surprisingly, careful isolation of compounds generated from the combination of components in an appropriate environment provide di- and tri-hydroxy EPA or DHA compounds having unique structural and physiological properties. The present invention therefore provides for many new useful therapeutic di- or tri-hydroxy derivatives of EPA or DHA (resolvins) that diminish, prevent, or eliminate inflammation or PMN migration, for example. The present invention also provides methods of use, methods of preparation, and packaged pharmaceuticals for use as medicaments for the compounds disclosed throughout the specification.Type: GrantFiled: October 28, 2013Date of Patent: January 13, 2015Assignee: The Brigham and Women's Hospital, Inc.Inventors: Charles N. Serhan, Bruce D. Levy
-
Patent number: 8933179Abstract: A method of producing a compound of formula (i): wherein R=H or CH3 the method comprising exposing a source of a compound of formula (ii) to reaction conditions of temperature and pressure: formula (ii) wherein R is defined as above wherein, when R=CH3, the source of a compound of formula (ii) is exposed to reaction conditions of temperature and pressure while being in a liquid phase.Type: GrantFiled: December 21, 2010Date of Patent: January 13, 2015Assignee: Lucite International UK LimitedInventors: David William Johnson, Graham Ronald Eastham, Martyn Poliakoff, Thomas Andrew Huddle
-
Patent number: 8927769Abstract: Methods and systems are provided for converting methane in a feed stream to acetylene. The method includes processing the acetylene to form a stream having acrylic acid. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is to be treated to convert acetylene to acrylic acid. The method according to certain aspects includes controlling the level of carbon monoxide to prevent undesired reactions in downstream processing units.Type: GrantFiled: June 11, 2013Date of Patent: January 6, 2015Assignee: UOP LLCInventors: Jeffery C. Bricker, John Q. Chen, Peter K. Coughlin
-
Patent number: 8895683Abstract: In one aspect, a process for the preparation of a superabsorbent polymer is described herein. In some embodiments, the process comprises (I) preparing acrylic acid, wherein the process comprises (a1) provision of a fluid F1 having a composition comprising from about 5 to about 20 wt. % of hydroxypropionic acid, salts thereof, or mixtures thereof; from about 0.1 to about 5 wt. % of inorganic salts; from about 0.1 to about 30 wt. % of organic compounds which differ from hydroxypropionic acid; from 0 to about 50 wt. % of solids; and from about 20 to about 90 wt. % of water; (a2) dehydration of said hydroxypropionic acid to give a fluid F2 containing acrylic acid; and (a3) purification of said fluid F2 to give a purified acrylic acid phase comprising acrylic acid having a purity of at least 70 wt. %; and (II) polymerizing the acrylic acid of (I) to form a superabsorbent polymer.Type: GrantFiled: May 17, 2013Date of Patent: November 25, 2014Assignee: Evonik Degussa GmbHInventors: Franz-Felix Kuppinger, Axel Hengstermann, Guido Stochniol, Gunther Bub, Jurgen Mosler, Andreas Sabbagh
-
Publication number: 20140316002Abstract: The present disclosure relates to lipid compounds of general formula (I) wherein R1 is chosen from a C10-C22 alkyl group, a C10-C22 alkenyl group having 1-6 double bonds, and a C10-C22 alkynyl group having 1-6 triple bonds; R2 and R3 are the same or different and may be selected from different substituents; Y is chosen from sulphur, sulfoxide, and sulfone; and X is a carboxylic acid or a derivative thereof, a carboxylic ester, a carboxylic anhydride, or a carboxamide; or a pharmaceutically acceptable salt, complex, or solvate thereof. The present disclosure also relates to pharmaceutical compositions and lipid compositions comprising such compounds, and methods of using such compounds such as for treating diseases related to cardiovascular, metabolic, and/or inflammatory diseases.Type: ApplicationFiled: April 28, 2014Publication date: October 23, 2014Applicant: PRONOVA BIOPHARMA NORGE ASInventors: Anne Kristin Holmeide, Ragnar HOVLAND, Morten BRÆNDVANG
-
Publication number: 20140288254Abstract: Provided herein is a non-naturally occurring microbial organism having a methanol metabolic pathway that can enhance the availability of reducing equivalents in the presence of methanol. Such reducing equivalents can be used to increase the product yield of organic compounds produced by the microbial organism, such as 3-hydroxyisobutyrate or MAA. Also provided herein are methods for using such an organism to produce 3-hydroxyisobutyrate or MAA.Type: ApplicationFiled: November 4, 2013Publication date: September 25, 2014Applicant: Genomatica, Inc.Inventors: Anthony P. Burgard, Robin E. Osterhout, Stephen J. Van Dien, Cara Ann Tracewell, Priti Pharkya, Stefan Andrae
-
Patent number: 8841481Abstract: The present invention relates to a process for preparing unsaturated aldehydes or unsaturated carboxylic acids by heterogeneous catalytic gas phase oxidation of unsaturated or saturated hydrocarbons, comprising the process steps of: i) providing a gas mixture comprising a saturated hydrocarbon and catalytically dehydrogenating the saturated hydrocarbon in the gas phase to obtain a gas mixture comprising an unsaturated hydrocarbon in a dehydrogenation reactor having a dehydrogenation catalyst material; or ii) providing a gas mixture comprising oxygen and an unsaturated hydrocarbon; iii) catalytically oxidizing the unsaturated hydrocarbon obtained in process step i) or provided in process step ii) in the gas phase to obtain a gas mixture comprising an unsaturated aldehyde in a first oxidation reactor having a first oxidation catalyst material; wherein at least one of the reactors selected from the dehydrogenation reactor, the first oxidation reactor and the second oxidation reactor comprises at least one foam bType: GrantFiled: July 29, 2009Date of Patent: September 23, 2014Assignee: Evonik Degussa GmbHInventors: Horst-Werner Zanthoff, Nicole Brausch, Franz-Felix Kuppinger, Jorg Sauer, Andreas Sabbagh, Dennis Fruhling, Markus Weber, Oliver Becker
-
Publication number: 20140275520Abstract: The invention provides a process of preparing 4-amino-4-oxobutanoyl peptides and cyclic analogues thereof of Compound I and pharmaceutically acceptable salts thereof.Type: ApplicationFiled: March 17, 2014Publication date: September 18, 2014Applicant: Achillion Pharmaceuticals, Inc.Inventors: Avinash Phadke, Akihiro Hashimoto
-
Publication number: 20140271946Abstract: Tobacco products comprising smokeless tobacco products and active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel are disclosed. Nicotine replacement therapies comprising active ingredients, including those that antagonize nicotinic acetylcholine receptors, the TRPV1 channel, and/or the TRPA1 channel. The active ingredient may reduce or eliminate sensory irritation arising due to use of the product. Analgesic compositions comprising active ingredients. Methods of reducing taste and sensory irritation by employing an active ingredient.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: ALTRIA CLIENT SERVICES INC.Inventors: Gerd Kobal, Georgios D. Karles, Munmaya K. Mishra
-
Publication number: 20140271488Abstract: Synthesis of compounds having varying degrees of conformational rigidity is obtained via a low cost, high yield and efficient synthetic reactions. The library of compounds is structurally diverse having at least one or more chiral centers and providing large numbers of compounds having building block diversity and substantial scaffold diversity. The compounds further provide a novel method for obtaining candidate therapeutic agents for prevention, treatment or diagnosis of diseases.Type: ApplicationFiled: September 7, 2012Publication date: September 18, 2014Applicant: The Scripps Research InstituteInventors: Glenn C. Micalizio, Thomas Kodadek, Mohosin Sarkar
-
Patent number: 8829134Abstract: A process for transporting a liquid monomer phase which has been withdrawn from a storage vessel and comprises methacrylic monomers to an extent of ?90% by weight, in a tank truck or in a tanker ship, in which the liquid monomer phase is subjected to a separating operation on the route from the storage vessel into the tank of a tank truck or of a tanker ship in order to separate polymer of the monomer present in dissolved form in the liquid monomer phase.Type: GrantFiled: March 21, 2008Date of Patent: September 9, 2014Assignee: BASF SEInventors: Joerg Heilek, Ulrich Hammon, Volker Schliephake, Klaus Joachim Mueller-Engel, Till Blum
-
Publication number: 20140239231Abstract: An environmentally beneficial process for the production of fuels and chemicals employs carbon dioxide from a natural source or from an artificial chemical source that would otherwise be discharged into the environment. The carbon dioxide is converted to formic acid and the formic acid is then non-biologically converted to fuels and/or chemicals without the intermediate process of hydrogenating the formic acid to methanol or reacting the formic acid with ammonia to form formamide. In the present process, formic acid is converted to one of seven primary feedstocks: formaldehyde, acrylic acid, methane, ethylene, propylene, syngas, and C5-C7 carbohydrates. The formaldehyde, acrylic acid, methane, ethylene, propylene, syngas and/or short chain carbohydrates can either be used directly, or can be converted into a wealth of other products.Type: ApplicationFiled: February 24, 2013Publication date: August 28, 2014Applicant: DIOXIDE MATERIALS, INC.Inventors: Richard I. Masel, Zheng Richard Ni, Qingmei Chen, Brian A. Rosen
-
Publication number: 20140228571Abstract: In a method of stabilizing acrylic compounds, a liquid phase containing at least one acrylic compound is mixed with at least one metal and at least one ligand. The acrylic compound can be acrylic acid, methacrylic acid, and their respective esters. The metal can be copper, manganese, and cerium. The ligand can be a quinoline compound of formula (I), an N-oxide of a compound of formula (I), 2,2?-bis(2,3-dihydro-3-oxoindolylidene), or an aliphatic y-dentate ligand with y being 2-6 and comprising at least two nitrogen atoms joined by aliphatic or aromatic C1-C4 bridges comprising y-2 further coordinating nitrogen atoms or heteroatoms: where X is OH, NH2, O—(C1-C4)-alkyl, O—C(O)—(C1-C4)-alkyl, or O—C(O)-phenyl; R1 is H, or (C1-C4)-alkyl; R2 is H, (C1-C4)-alkyl, Cl, Br, or SO3H; and R3 is H, Cl or Br.Type: ApplicationFiled: December 12, 2013Publication date: August 14, 2014Applicant: BASF SEInventors: Tobias Johannes KORN, Peter Zurowski, Thorsten Friese, Sylke Haremza, Ulrich Jäger, Steffen Rissel, Volker Schliephake
-
Publication number: 20140194559Abstract: The invention concerns a formulation and method which allow for the efficient delivery of antipolymerants of low solubility into processes for the production of ethylenically unsaturated monomers, and associated process streams, and which avoid the potential health and safety problems and economic disadvantages which are associated with the methods of the prior art and facilitate the safe and efficient production of these monomers. Specifically, the invention provides an antipolymerant composition for the prevention of unwanted polymerisation reactions during the production and processing of ethylenically unsaturated compounds, the composition comprising a concentrated liquid formulation, wherein said concentrated liquid formulation is a suspension concentrate which comprises: (a) at least one compound selected from the group comprising phenols, quinones, thiazines, hydroxylamines and aromatic amines; (b) at least one dispersing agent; and (c) at least one polar or non-polar liquid carrier.Type: ApplicationFiled: August 20, 2012Publication date: July 10, 2014Applicant: NuFarm UK LimitedInventors: Peter Price, Guillaume Duchamp, Angela Jane Glossop, Andrew Nigel Fawbert, Stephanie Mary Dwyer
-
Publication number: 20140179942Abstract: The invention relates to a micro-organism comprising a hydrogenase enzyme system which is capable of converting carbon dioxide into formic acid and a second enzyme system which is capable of converting formic acid into aliphatic carboxylic acids having a chain length of five or more carbon atoms. Also described are various methods for producing oil, as well as other aspects of the invention.Type: ApplicationFiled: July 13, 2012Publication date: June 26, 2014Applicant: VERDANT BIOPRODUCTS LIMITEDInventor: Irene Finnegan
-
Publication number: 20140162345Abstract: Processes for converting lignocellulose to feedstock and downstream products are disclosed. The processes may include acid treatment of lignocellulose to produce a fermentation feedstock. In various instances, the processes include recovery or recycling of acid, such as recovery of hydrochloric acid from concentrated and/or dilute streams. Downstream products may include acrylic acid-based products such as diapers, paper and paper-based products, ethanol, biofuels such as biodiesel and fuel additives, and detergents.Type: ApplicationFiled: April 2, 2012Publication date: June 12, 2014Inventor: Aharon Eyal
-
Patent number: 8748545Abstract: The present invention relates to the manufacture of bioresourced polymer-grade acrylic acid from glycerol. The polymer grade acrylic acid produced has limited content of certain impurities harmful to polymerization processes, such as, total aldehydes, protoanemonin, maleic anhydride and nonphenolic polymerization inhibitors. The invention also relates to the use of the bioresourced acrylic acid obtained for manufacture of superabsorbents or for manufacture of polymers or copolymers using amide or ester derivatives of the bioresourced acrylic acid.Type: GrantFiled: September 14, 2009Date of Patent: June 10, 2014Assignee: Arkema FranceInventors: Jean-Francois Devaux, Michel Fauconet, Denis Laurent
-
Publication number: 20140147481Abstract: The invention provides novel compositions based on a structure designated as “Honaucin A”, including Honaucin A variants and analogs, and pharmaceutical compositions, liposomes and nanoparticles comprising them, and methods of making and using them. In one embodiment these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used as bacterial quorumsensing inhibitors. Accordingly, in alternative embodiments the compositions of the invention are used as anti-bacterial agents.Type: ApplicationFiled: June 3, 2011Publication date: May 29, 2014Applicants: UNIVERSITY OF RHODE ISLAND RESEARCH FOUNDATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: William Gerwick, Lena Gerwick, Huykjae Choi, Francisco Villa, Jennifer Smith, David C Rowley
-
Patent number: 8729299Abstract: In one embodiment, the invention is to a process for producing an acrylate product. The process comprises the step of reacting a reaction mixture comprising an alkanoic acid, an alkylenating agent, and oxygen over a catalyst and under conditions effective to form a crude acrylate product. Preferably, the reaction mixture comprises from 0.5 wt % to 10 wt % oxygen. The crude acrylate product comprises acrylate product and alkylenating agent. The process further comprises the step of separating at least a portion of the crude product to form at least one alkylenating agent stream and at least one purified acrylate product stream. The purified acrylate product stream comprises acrylate product.Type: GrantFiled: March 23, 2012Date of Patent: May 20, 2014Assignee: Celanese International CorporationInventors: Sean Mueller, Josefina Chapman, Craig Peterson, Dick Nagaki
-
Publication number: 20140135526Abstract: Methods of obtaining mutant nucleic acid sequences that demonstrate elevated oxaloacetate a-decarboxylase activity are provided. Compositions, such as genetically modified microorganisms that comprise such mutant nucleic acid sequences, are described, as are methods to obtain the same.Type: ApplicationFiled: October 30, 2013Publication date: May 15, 2014Applicant: OPX Biotechnologies, Inc.Inventor: Michael D. Lynch
-
Publication number: 20140121399Abstract: The polymerization of monomers may be at least partially reduced or inhibited by introducing an effective amount of an additive. The additive may be or include a first compound: where: R1 and R2 may be or include an alkyl group, an aryl group, an alkyl group having a heteroatom, an aryl group having a heteroatom, and combinations thereof. The hetero atom may be or include sulfur, nitrogen and/or oxygen. R1 may be the same or different from R2. The polymerizable monomers may be or include, but are not limited to styrene, butadiene, isoprene, acrylic acid, acrylonitrile, vinyl acetate, and combinations thereof.Type: ApplicationFiled: October 25, 2012Publication date: May 1, 2014Applicant: BAKER HUGHES INCORPORATEDInventors: Hua Mo, Roger D. Metzler
-
Patent number: 8704000Abstract: PROBLEM There is provided a melting method of (meth)acrylic acid crystal which is capable of providing a higher quality of (meth)acrylic acid without carrying out an additional purification treatment to (meth)acrylic acid obtained by a crystallization operation accompanied by melting of (meth)acrylic acid. In addition, there is provided a simple method for adjusting a content of polymerization inhibitor in a product (meth)acrylic acid. SOLUTION In the crystallization method melting (meth)acrylic acid crystal while wetting with the crystalline molten liquid, a polymerization inhibitor is added to a molten liquid melted after initiation of melting, and all of crystal is melted while circulating and feeding the molten liquid containing said polymerization inhibitor to the crystal.Type: GrantFiled: May 27, 2010Date of Patent: April 22, 2014Assignee: Nippon Shokubai Co., Ltd.Inventors: Kazuhiko Sakamoto, Koji Ueno, Yoshitake Ishii, Harunori Hirao, Satoshi Nakagawa
-
Publication number: 20140107377Abstract: This invention relates to microorganisms that convert a carbon source to acrylate or other desirable products using propionyl-CoA as an intermediate. The invention provides genetically engineered microorganisms that carry out the conversion, as well as methods for producing acrylate by culturing the microorganisms. Also provided are microorganisms and methods for converting propionyl-CoA and propionate to 3-hydroxypropionyl-CoA, 3-hydroxypropionate (3-HP) and poly-3-hydroxypropionate.Type: ApplicationFiled: October 15, 2012Publication date: April 17, 2014Applicant: THE PROCTER & GAMBLE COMPANYInventors: Jun Xu, Phillip Richard Green, Charles Winston Saunders, Juan Estaban Velasquez
-
Patent number: 8685682Abstract: An engineered strain of the oleaginous yeast Yarrowia lipolytica capable of producing greater than 5.6% docosahexaenoic acid acid (DHA, an w-3 polyunsaturated fatty acid) in the total oil fraction is described. This strain comprises various chimeric genes expressing heterologous desaturases, elongases and acyltransferases and optionally comprises various native desaturase and acyltransferase knockouts to enable synthesis and high accumulation of DHA. Production host cells are claimed, as are methods for producing DHA within said host cells.Type: GrantFiled: May 14, 2009Date of Patent: April 1, 2014Assignee: E I du Pont de Nemours and CompanyInventors: Howard Glenn Damude, Peter John Gillies, Daniel Joseph Macool, Stephen K Picataggio, James John Ragghianti, John E Seip, Zhixiong Xue, Narendra S Yadav, Hongxiang Zhang, Quinn Qun Zhu
-
Publication number: 20140087978Abstract: A method of converting an inactive biocide into an active biocide comprises: contacting the inactive biocide with an activating agent, wherein the activating agent is capable of chemically reacting with the inactive biocide; and causing or allowing a chemical reaction to take place between the inactive biocide and the activating agent, wherein the chemical reaction produces the active biocide. The methods can also include deactivating the active biocide via a chemical reaction between the active biocide and a deactivating agent.Type: ApplicationFiled: September 27, 2012Publication date: March 27, 2014Applicant: HALLIBURTON ENERGY SERVICES, INCInventor: Jay P. DEVILLE
-
Publication number: 20140058133Abstract: Methods and systems are provided for converting methane in a feed stream to acetylene. The method includes processing the acetylene to form a stream having acrylic acid. The hydrocarbon stream is introduced into a supersonic reactor and pyrolyzed to convert at least a portion of the methane to acetylene. The reactor effluent stream is be treated to convert acetylene to acrylic acid. The method according to certain aspects includes controlling the level of carbon monoxide to prevent undesired reactions in downstream processing units.Type: ApplicationFiled: June 11, 2013Publication date: February 27, 2014Inventors: Jeffery C. Bricker, John Q. Chen, Peter K. Coughlin