Patents by Inventor Julius F. Remenar

Julius F. Remenar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic Compounds for the Treatment of Neurological and Psychological Disorders
    Publication number: 20140350254
    Abstract: Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed.
    Type: Application
    Filed: June 5, 2014
    Publication date: November 27, 2014
    Inventors: Julius F. Remenar, Laura Cook Blumberg, Tarek A. Zeidan
  • Prodrugs of NH-Acidic Compounds
    Publication number: 20140221653
    Abstract: The invention provides a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods of the invention are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties. The prodrug compounds of the invention can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment.
    Type: Application
    Filed: February 4, 2014
    Publication date: August 7, 2014
    Applicant: Alkermes Pharma Ireland Limited
    Inventors: Laura Cook Blumberg, Julius F. Remenar, Orn Almarsson, Tarek A. Zeidan
  • Heterocyclic compounds for the treatment of neurological and psychological disorders
    Patent number: 8796276
    Abstract: Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: August 5, 2014
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Julius F. Remenar, Laura Cook Blumberg, Tarek A. Zeidan
  • Co-crystal of etravirine and nicotinamide
    Patent number: 8754093
    Abstract: Etravirine (TMC125) nicotinamide co-crystal, its preparation, and use in the treatment of HIV infection.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: June 17, 2014
    Assignee: Janssen R&D Ireland
    Inventors: Matthew F. Sansone, Mark Tawa, Julius F. Remenar, Lieven Elvire Colette Baert
  • PRODRUGS OF NH-ACIDIC COMPOUNDS: ESTER, CARBONATE, CARBAMATE AND PHOSPHONATE DERIVATIVES
    Publication number: 20140094472
    Abstract: The invention provides a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods of the invention are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties. The prodrug compounds of the invention can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment.
    Type: Application
    Filed: September 24, 2013
    Publication date: April 3, 2014
    Applicant: Alkermes Pharma Ireland Limited
    Inventors: Laura Cook Blumberg, Julius F. Remenar, Orn Almarsson, Tarek A. Zeidan
  • Prodrugs of NH-acidic compounds
    Patent number: 8686009
    Abstract: The invention provides a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods of the invention are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties. The prodrug compounds of the invention can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: April 1, 2014
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Laura Cook Blumberg, Julius F. Remenar, Örn Almarsson, Tarek A. Zeidan
  • PHARMACEUTICAL COMPOSITIONS HAVING IMPROVED STORAGE STABILITY
    Publication number: 20140088115
    Abstract: The present invention relates to a pharmaceutical composition that provides long-term stability of a hydrolytically labile antipsychotic agent
    Type: Application
    Filed: September 19, 2013
    Publication date: March 27, 2014
    Applicant: ALKERMES PHARMA IRELAND LIMITED
    Inventors: Jason M. Perry, Daniel R. Deaver, Magali B. Hickey, Julius F. Remenar, Jennifer Vandiver, Michael J. Palmieri, JR., Zhengzheng Pan
  • Process for Synthesizing Oxidized Lactam Compounds
    Publication number: 20140051852
    Abstract: The invention provides a method for the synthesis of dehydrogenated lactam drugs of Formula I:
    Type: Application
    Filed: August 2, 2013
    Publication date: February 20, 2014
    Applicant: Alkermes Pharma Ireland Limited
    Inventors: Julius F. Remenar, Laura Cook Blumberg, Tarek A. Zeidan
  • Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
    Patent number: 8592427
    Abstract: The invention provides a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods of the invention are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties. The prodrug compounds of the invention can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: November 26, 2013
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Laura Cook Blumberg, Julius F. Remenar, Örn Almarsson, Tarek A. Zeidan
  • PHARMACEUTICAL COMPOSITIONS COMPRISING BENZYL ALCOHOL
    Publication number: 20130267505
    Abstract: The present invention relates to a pharmaceutical composition comprising benzyl alcohol and polyoxyethylene derivatives of sorbitan esters of carboxylic acids that are useful for the delivery of anti-psychotic drugs.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 10, 2013
    Applicant: ALKERMES PHARMA IRELAND LIMITED
    Inventors: Jason M. PERRY, Magali B. HICKEY, Julius F. REMENAR, Jennifer VANDIVER
  • PHARMACEUTICAL COMPOSITIONS COMPRISING FATTY GLYCEROL ESTERS
    Publication number: 20130267504
    Abstract: The present invention relates to a pharmaceutical composition comprising glycerol esters of a fatty acid, wherein the compositions are useful for the delivery of anti-psychotic drugs.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 10, 2013
    Applicant: ALKERMES PHARMA IRELAND LIMITED
    Inventors: Jason M. PERRY, Magali B. HICKEY, Julius F. REMENAR, Jennifer VANDIVER
  • PHARMACEUTICAL COMPOSITIONS COMPRISING FATTY ACID ESTERS
    Publication number: 20130267503
    Abstract: The present invention relates to an injectable, pharmaceutical composition comprising a C1-6 alkyl ester of a C10-20 fatty acid. In an embodiment, the fatty acid is ethyl oleate, isopropyl oleate, ethyl myristate, or isopropyl myristate. These compositions are useful for the delivery of anti-psychotic drugs.
    Type: Application
    Filed: March 13, 2013
    Publication date: October 10, 2013
    Applicant: ALKERMES PHARMA IRELAND LIMITED
    Inventors: Jason M. PERRY, Magali B. HICKEY, Julius F. REMENAR, Jennifer VANDIVER
  • Process for synthesizing oxidized lactam compounds
    Patent number: 8536328
    Abstract: The invention provides a method for the synthesis of dehydrogenated lactam drugs of Formula I:
    Type: Grant
    Filed: May 4, 2011
    Date of Patent: September 17, 2013
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Julius F. Remenar, Laura Cook Blumberg, Tarek A. Zeidan
  • Pharmaceutical forms, and methods of making and using the same
    Patent number: 8436029
    Abstract: Crystalline salts, polymorphs, solvates, and hydrates of bicalutamide, 5-fluorouracil, donepezil, anastrozole, nelfinavir, mirtazapine, lansoprazole, and tamsulosin, or derivatives thereof are provided by the subject invention. Methods of making and using the same are also provided.
    Type: Grant
    Filed: March 17, 2005
    Date of Patent: May 7, 2013
    Assignees: Transform Pharmaceuticals, Inc., University of South Florida
    Inventors: Magali Bourghol Hickey, Matthew L. Peterson, Örn Almarsson, Michael J. Zaworotko, Tanise Shattock, Julius F. Remenar, Mark Tawa
  • Heterocyclic compounds for the treatment of neurological and psychological disorders
    Patent number: 8431576
    Abstract: Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: April 30, 2013
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Julius F. Remenar, Laura Cook Blumberg, Tarek A. Zeidan
  • Heterocyclic Compounds for the Treatment of Neurological and Psychological Disorders
    Publication number: 20130096089
    Abstract: Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed.
    Type: Application
    Filed: September 7, 2012
    Publication date: April 18, 2013
    Inventors: Julius F. Remenar, Laura Cook Blumberg, Tarek A. Zeidan
  • Hydrated sodium salt form of celecoxib
    Patent number: 8410287
    Abstract: Hydrated celecoxib sodium salt forms and processes to prepare hydrated celecoxib sodium salt forms are disclosed. The celecoxib sodium salt forms are particularly useful and suitable for pharmaceutical applications.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: April 2, 2013
    Assignee: McNeil-PPC, Inc.
    Inventors: Julius F. Remenar, Mark D. Tawa, Matthew L. Peterson
  • PHARMACEUTICAL COMPOSITIONS COMPRISING SORBITAN ESTERS
    Publication number: 20120238552
    Abstract: The present invention relates to a pharmaceutical composition comprising sorbitan esters of carboxylic acids that are useful for the delivery of anti-psychotic drugs.
    Type: Application
    Filed: March 19, 2012
    Publication date: September 20, 2012
    Applicant: ALKERMES, INC.
    Inventors: Jason M. PERRY, Daniel R. DEAVER, Magall B. HICKEY, Julius F. REMENAR, Jennifer VANDIVER
  • Hydrated Sodium Salt Form of Celecoxib
    Publication number: 20120029205
    Abstract: Hydrated celecoxib sodium salt forms and processes to prepare hydrated celecoxib sodium salt forms are disclosed. The celecoxib sodium salt forms are particularly useful and suitable for pharmaceutical applications.
    Type: Application
    Filed: July 29, 2011
    Publication date: February 2, 2012
    Applicant: MCNEIL-PPC, INC.
    Inventors: Julius F. Remenar, Mark D. Tawa, Matthew L. Peterson
  • CO-CRYSTAL OF ETRAVIRINE AND NICOTINAMIDE
    Publication number: 20120028998
    Abstract: Etravirine (TMC125) nicotinamide co-crystal, its preparation, and use in the treatment of HIV infection.
    Type: Application
    Filed: March 26, 2010
    Publication date: February 2, 2012
    Inventors: Matthew F. Sansone, Lieven Elvire Colette Baert, Mark Tawa, Julius F. Remenar