Abstract: An improved catheter insertion assembly having a transparent tubular member open at each end; a plunger assembly slidable within the tubular member having a stem portion at a first end; and at least a partially transparent chamber having a needle base and sealing member on a second end of the plunger assembly; an elongated tubular needle embedded within the needle base and extending there from with the needle in fluid communication with the transparent chamber; a catheter assembly, a transparent cannula and a transparent hub attached to the second end with the tubular needle passing longitudinally through the cannula; a fluid passage formed between the needle and the cannula so that when the plunger is retracted a vacuum is established within the fluid passage and blood is visibly drawn through the fluid passage into the transparent cannula and if volume permits, blood then would be visible in the transparent hub, and then if volume permits blood would be visible in the void of the catheter body (barrel) crea

Abstract: An apparatus includes a disposable assembly and a reusable assembly. The disposable assembly includes a fluid input port, a fluid output port, and a tube configured to provide fluid communication between the fluid input port and the fluid output port. The reusable assembly includes a housing, a fluid management assembly that is configured to transition between an open position and a closed position, and a sensing assembly. The fluid management assembly is configured to prevent fluid from traveling past the tube to the fluid output port in the closed position. The sensing assembly is configured to sense fluid accumulating within the tube while the fluid management assembly is in the closed position. The sensing assembly is also configured to drive the fluid management assembly from the closed position to the open position when the sensing assembly detects fluid within the tube at a predetermined range.

Abstract: Disclosed is a method for controlling an auto injector and an auto injector for administering a medicament from a cartridge having a first cartridge end and a second cartridge end and having a cartridge outlet at the first cartridge end, the cartridge comprising a cartridge compartment with a first cartridge subcompartment containing a first medicament component of the medicament and a second cartridge subcompartment containing a second medicament component of the medicament. The auto injector comprises: a housing; a cartridge receiver; a cartridge sensor; a drive module; an orientation sensor; and a processing unit.

Abstract: The present disclosure provides methods for determining whether a patient exhibiting cystic fibrosis symptoms, or a patient at risk for cystic fibrosis, will benefit from treatment with one or more anti-cystic fibrosis therapeutic agents. These methods are based on detecting hereditary cystic fibrosis related mutations in small-volume dried biological fluid samples that are collected using a volumetric absorptive microsampling device. Kits for use in practicing the methods are also provided.

Abstract: The present disclosure provides rapid and non-invasive methods for determining whether a patient exhibiting cancer symptoms, or at risk for hereditary cancers such as breast cancer, ovarian cancer, colon cancer, or skin cancer, will benefit from treatment with one or more therapeutic agents. These methods are based on detecting hereditary cancer-related mutations in small-volume dried biological fluid samples that are collected using a volumetric absorptive microsampling device (e.g., MITRA Tip). Kits for use in practicing the methods are also provided.

Abstract: The present disclosure provides rapid and non-invasive methods for determining whether a patient exhibiting cancer symptoms, or at risk for hereditary cancers such as breast cancer, ovarian cancer, colon cancer, or skin cancer, will benefit from treatment with one or more therapeutic agents. These methods are based on detecting hereditary cancer-related mutations in small-volume dried biological fluid samples that are collected using a volumetric absorptive microsampling device (e.g., MITRA Tip). Kits for use in practicing the methods are also provided.

Abstract: An apparatus and associated methods relate to an external catheter configured with a urine collection bag having a semi-rigid and flexible internal tube adapted to permit fluid engagement with urine streaming from a patient, in a manner that does not require precisely locating a patient's buried, retracted or retractive penis supported by secure connection to the patient coincident to the outer circumference of the internal tube with an adhesive having a removable non-adhesive backing to prevent the dislodging or misplacement of the external catheter or obstruction of the flow of urine and the secure attachment of the tube to a transparent urine collection bag permitting visualization of the inner contents of the bag.

Abstract: Bodily fluid sample collection systems, devices, and method are provided. The sample is collected at a first location and subjected to a first sample processing step. The sample may be shipped to a second location and subjected to a second sample processing step that does not introduce contaminants into a plasma portion of the sample formed from the first processing step. The sample may also be mixed with other material(s) in the collection device.

Abstract: A sealed medication dispensing and administering device has a syringe, a plunger, a connecting holder, an elastic valve, and a liquid stopper. The syringe has an outer barrel having an air inlet tube and an inner barrel inserted inside the outer barrel and having a medication inlet tube. The plunger is inserted within the outer and inner barrels. The connecting holder is connected to the syringe and has a connecting cover with at least one outer connecting hole and two piercing needles respectively piercing inside the air inlet tube and the medication inlet tube. Inner spaces of the two piercing needles communicate with the at least one outer connecting hole. The elastic valve selectively covers the two piercing needles. The fluid stopper is disposed within the connecting cover and blocks one of the at least one outer connecting hole and the inner space of the air inlet tube.

Abstract: An apparatus includes a pre-sample reservoir, a diversion mechanism, and a flow metering mechanism. The diversion mechanism has an inlet port couplable to a lumen-defining device to receive bodily-fluids from a patient, a first outlet port fluidically couplable to the pre-sample reservoir, and a second outlet port fluidically couplable to a sample reservoir. The diversion mechanism defines a first fluid flow path and a second flow path that are configured to place the first outlet port and the second outlet port, respectively, in fluid communication with the inlet port. The flow metering mechanism is configured to meter a flow of a predetermined volume of bodily-fluid through the first fluid flow path into the pre-sample reservoir, to meter a flow of a second volume of bodily-fluid through the second fluid flow path into the sample reservoir, and to display a volumetric indicator associated with the predetermined volume and the second volume.

Abstract: A vapor delivery needle is provided that may include any of a number of features. One feature of the energy delivery probe is that it can apply condensable vapor energy to tissue, such as a prostrate, to shrink, damage, denaturate the prostate. In some embodiments, the vapor delivery needle can be advanced a predetermined distance into the prostate with a solenoid actuation mechanism. Methods associated with use of the energy delivery probe are also covered.

Abstract: The purpose of the invention is to create a urine bag that can be easily folded in order to occupy less space prior to use and that can be easily manipulated by a patient, in particular a paraplegic patient. This is achieved using a urine collection bag (1) formed by two sheets of plastic material that are stacked and welded along the periphery (2) thereof. The collection bag (1) comprises a collection compartment (3), said inlet being in communication with the intake port (4) and delimiting the upper portion of the collection compartment (3). The intake port (4) is provided with a vertical extension (8) closed along their periphery (22) thereof and comprising a urinary catheter (9). The bag (1) of the invention is characterised in that the intake port (4) and the inlet (6) are offset vertically, and in that the vertical height (ho) of the bag (1) corresponds to a multiple of the height (hp) of the extension (8).

Abstract: An improved catheter insertion assembly having a transparent tubular member open at each end; a plunger assembly slidable within the tubular member having a stem portion at a first end; and at least a partially transparent chamber having a needle base and sealing member on a second end of the plunger assembly; an elongated tubular needle embedded within the needle base and extending there from with the needle in fluid communication with the transparent chamber; a catheter assembly, a transparent cannula and a transparent hub attached to the second end with the tubular needle passing longitudinally through the cannula; a fluid passage formed between the needle and the cannula so that when the plunger is retracted a vacuum is established within the fluid passage and blood is visibly drawn through the fluid passage into the transparent cannula and if volume permits, blood then would be visible in the transparent hub, and then if volume permits blood would be visible in the void of the catheter body (barrel) crea

Abstract: In a first aspect, there is a device for detecting a substance within blood, including a collecting tube dimensioned to draw in blood through capillary action; a reagent chamber containing a reactive element; and a connector tube providing fluid communication between the reagent chamber and the collecting tube; wherein the connector tubes are dimensioned to draw in blood through capillary action to the reagent chamber. In other aspects, the device can include an outer casing and/or a plurality of reagent chambers each with a reactive element therein.

Abstract: A medical device includes a hollow shaft, a hollow housing, and a syringe. The syringe has a housing defining a fluid receiving chamber and a plunger slidably received therein. The shaft extending distally from the plunger and exiting the syringe via a distal opening therein. A proximal portion of the shaft includes a first opening permitting fluid flow from a central lumen of the shaft to an exterior thereof. The first opening is located on the shaft so that the first opening remains within the syringe through an entire range of motion of the plunger. A distal end of the shaft is surrounded by an absorbent material. The hollow housing extends distally from the syringe and surrounding the shaft. The housing is sized so that, when the plunger is withdrawn to a proximal-most position, the distal end is received within the housing and, when the plunger is advanced distally through the syringe, the distal end is extended distally out of a distal opening in the housing.

Abstract: A fluid collection device includes an upper edge portion having a first end of a collection container having an outer surface where the upper edge portion defines an open top end. At least one fastening device may be attached to the outer surface of the collection container. A vacuum hose coupled to an outlet port extends from a second end of the collection container. A vacuum source applies a vacuum to the collection container through the vacuum hose.

Abstract: An isolation device of target particles from a liquid sample includes an isolation chip, a vacuum unit, and a frequency converting unit. The isolation chip includes a sample reservoir, a first chamber, and a second chamber. The first chamber and the second chamber define a first outlet and a second outlet, respectively. The vacuum unit is connected to the first outlet and the second outlet. The frequency converting unit causes the vacuum unit to generate negative pressures in the first chamber and the second chamber alternately.

Abstract: A perimeter fill syringe is disclosed, wherein the syringe includes a solid core, allowing fluid to fill an area around the perimeter of the syringe barrel, enabling a wider diameter for the barrel thus increasing the visibility of the markings and ease of handling by a user.

Abstract: A specimen collection assembly (100) including a flow control member (106) for adjustably altering a flow path is disclosed. In one configuration, the flow control member (106) defines a regulation channel (166) in fluid communication with a lumen of a cannula (112), wherein the flow control member (106) is configured to adjustably alter an effective flow distance between the lumen of the cannula (112) and an interior of an evacuated collection container. In another configuration, the flow control member (106) is positioned to vary an effective cross-sectional area of at least one of an inlet port (346) and an outlet port (350) adapted to be in fluid communication with the lumen and the evacuated collection container.

Abstract: A tube assembly for monitoring a fluid dispensed into a fluid fill port is disclosed. The tube assembly may include a tube body disposed between a first and second open end. A locking portion including a circumferential groove may be defined adjacent to the first open end and a fill portion may be defined at the second open end of the tube body. An aperture may extend through an outer surface of the tube body and a sensor may be inserted into the aperture such that at least a portion of the sensor is positioned within the interior portion of the tube body. The sensor may be configured to monitor at least one fluid characteristic of the fluid that is dispensed into the tube assembly and flows into the fluid fill port.

Abstract: An apparatus and method for the treatment of stress urinary incontinence. The apparatus includes a suburethral sling having an adjustment member for adjusting the tension of the sling both during the procedure and post-procedure. The method includes using a needle to simultaneously implant the sling and to deliver a local anesthetic in the groin area while implanting the sling.

Abstract: Bodily fluid sample collection systems, devices, and method are provided. The sample is collected at a first location and subjected to a first sample processing step. The sample may be shipped to a second location and subjected to a second sample processing step that does not introduce contaminants into a plasma portion of the sample formed from the first processing step. The sample may also be mixed with other material(s) in the collection device.

Abstract: The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media.

Abstract: A multi-function cooling and thermo-sensitive rack includes horizontal bars, a base, positioning holes, connectors, a lateral frame, connecting holes, a temperature-displaying prompter, and N temperature sensors. The lateral frame and the base are connected through the connectors. The lateral frame and the base have their surfaces facing each other symmetrically provided with plural connecting holes thereon. The horizontal bars have two ends thereof received in the corresponding symmetrical connecting holes. The positioning holes are distributed over the surface of the base. The N temperature sensors have output ends thereof for outputting sensing signals connected with input ends of the temperature-displaying prompter for inputting the N temperature-sensing signals. The present invention is applied to apparatuses used in microbiology experiment.

Abstract: An apparatus includes a pre-sample reservoir, a diversion mechanism, and a flow metering mechanism. The diversion mechanism has an inlet port couplable to a lumen-defining device to receive bodily-fluids from a patient, a first outlet port fluidically couplable to the pre-sample reservoir, and a second outlet port fluidically couplable to a sample reservoir. The diversion mechanism defines a first fluid flow path and a second flow path that are configured to place the first outlet port and the second outlet port, respectively, in fluid communication with the inlet port. The flow metering mechanism is configured to meter a flow of a predetermined volume of bodily-fluid through the first fluid flow path into the pre-sample reservoir, to meter a flow of a second volume of bodily-fluid through the second fluid flow path into the sample reservoir, and to display a volumetric indicator associated with the predetermined volume and the second volume.

Abstract: An automatic mixing device, an actuating device having integrated plunger and configured to be removably mounted to the automatic mixing device, and a retractable syringe having the automatic mixing device are provided. The actuating device has an initially compressed spring and a trigger member that is rotatable to initiate spring decompression to drive depression of a mixing plunger seal of the automatic mixing device. Another seal located in an outer chamber of the mixing device is capable of axial movement upon depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in an inner barrel to a second position intermediate the apertures and vents in an outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in an inner chamber of the inner barrel. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction.

Abstract: A medicament delivery device includes a case, a first plunger, a second plunger arranged telescopically with the first plunger, a first drive spring biasing the second plunger relative to the case, and a second drive spring biasing the first plunger relative to the second plunger.

Abstract: A sample preparation device, preferably for sterility testing, comprising a manifold including one or more receptacles for filtration units and at least one inlet and/or outlet port. The receptacle(s) is/are respectively provided with one or more connectors for establishing a fluid connection with mating ports of the filtration units and media containers/vials upon insertion of the same into the respective receptacles. The connectors are in fluid communication with the inlet and outlet port(s) via channels defined in the manifold to allow a desired fluid transfer through the manifold.

Abstract: An integrated sampling and detecting device is provided. The device has a detector; a test strip holder, detachably provided in the detector; a collector, detachably contained in the detector; a faeces sample piece and a cushion block, for detachably sealing the collector; and a piercing part, provided on a bottom surface of the detector and configured to pierce the collector. The test strip holder and the collector are contained in the detector side by side. The collector is located between the test strip holder and the detector. A first outer side face of the collector is adjacent to an inner side wall of the detector. A second outer side face of the collector is adjacent to the test strip holder. A horizontal cross-section of the piercing part adapts to a bottom surface of the collector.

Abstract: The invention relates to a transdermal microneedle array patch for measuring a concentration of a hypodermal target molecule. The transdermal microneedle array patch includes a substrate, a microneedle unit, a signal processing unit and a power supply unit. The microneedle unit at least comprises a first microneedle set used as a working electrode and a second microneedle set used as a reference electrode, the first and second microneedle sets arranging on the substrate. Each microneedle set comprises at least a microneedle. The first microneedle set comprises at least a sheet having a through hole on which a barbule forms at the edge. One of the sheet provides the through hole from which the barbules at the edge of the other sheets go through, and the barbules are disposed separately.

Abstract: A closure device operable to seal a vessel puncture and including a delivery member and a sealant material applicator. The delivery member is insertable through a tissue tract to the vessel puncture. The sealant material applicator is configured to supply a volume of sealant material to the delivery member and includes a housing, a plunger assembly, and at least one container. The housing includes at least first and second chambers, wherein the first chamber carries a first sealant component and the second chamber carries a second sealant component. The container is insertable into the first or second chamber and carries a third sealant component of the sealant material. The sealant material applicator creates flow communication between the container and at least one of the first and second chambers to mix the third sealant component with the first and second sealant components.

Abstract: The present invention is directed to the parenteral procurement of bodily-fluid samples. The present invention is also directed to systems and methods for parenterally procuring bodily-fluid samples with reduced contamination from dermally-residing microbes. In some embodiments, a bodily-fluid withdrawing system is used to withdraw bodily fluid from a patient for incubation in culture media in one or more sample vessels. Prior to withdrawing bodily fluid into the one or more sample vessels for incubation, an initial volume of withdrawn bodily fluid is placed in one or more pre-sample reservoirs and is not used for the incubation in culture media.

Abstract: The present specification discloses filtration devices for processing a biofluid sample, methods of purifying a biofluid sample using the disclosed filtration devices, and systems comprising components of the filtration devices. The filtration device generally includes a collection container, a quantitative container, a filter, and a plunger slidably inserted through a plunger attachment. In a first configuration, the quantitative container is axially slidably inserted within the collection chamber, with fluid communication between the quantitative chamber and the collection chamber provided through the filter. In a second configuration, the filter and the collection container are separated from the quantitative container, the plunger attachment is fitted to the quantitative chamber open end with at least a portion of the plunger positioned within the quantitative chamber.

Abstract: This invention is a device that utilizes hydro-block venting material in various condom catheter configurations to permit adequate airflow into the catheter thereby permitting efficient and complete drainage of urine away from the user following urination by means od gravity, siphoning or pumping. In one embodiment the condom that fits on the penis is itself made of hydro-block venting material. In another embodiment the hydro-block material is placed on the proximal end of a storage bag. In yet another embodiment a retro-fit assembly containing the hydro-block venting material can be retrofitted for use with any condom catheter. Both adhesive and inflatable rings are disclosed as attachment means to secure the condom catheter to the user and prevent leakage.

Abstract: Described here are meters and methods for sampling, transporting, and/or analyzing a fluid sample. The meters may include a meter housing and a cartridge. In some instances, the meter may include a tower which may engage one or more portions of a cartridge. The meter housing may include an imaging system, which may or may not be included in the tower. The cartridge may include one or more sampling arrangements, which may be configured to collect a fluid sample from a sampling site. A sampling arrangement may include a skin-penetration member, a hub, and a quantification member.

Abstract: A syringe is disclosed.

Abstract: A blood collection apparatus is provided with a blood collection assembly including a casing tube including a forward nose, a plurality of connectors and a rear flange having a flexible projection, a plunger slidably disposed in the casing tube and including a forward plug and an elongated arm having a plurality of cavities, a blood collection tubes, an adapter assemblies each including a tube body, a first tube extending out of one end and insert into a related connectors of the casing tube, a second tube extending out of the end to insert into one of the blood collection tubes, and a butterfly needle assembly mounted to the nose of the casing tube. A pulling of the plunger moves the plug rearward and pivots the projection to engage in one cavity of the elongated arm and an orifice of the each related connectors is not blocked by the plug so as to flow blood from the tube casing to one of the blood collection tube via one connector and one adapter assembly.

Abstract: The invention relates to a dispense interface for an ejection device comprising a first part and a second part, at least a first opening, a second opening and a third opening, a fluidic channel and a connection element for each of the openings, wherein the first part is joined to the second part to form at least a part of the fluidic channel connecting the openings with each other and wherein at least one connection element is configured to accept a needle assembly for a fluid tight connection with the corresponding opening and wherein at least one connection element is configured to provide a releasable push fit connection for a fluid tight connection with an ejection device in order to reduce the complexity and provide an easy usage of the dispense interface and at the same time overcome the problems of material compatibility and cross contamination. The invention also relates to a system with a dispense interface according to the invention.

Abstract: The present invention relates to a device and method for easy collection, dilution, mixing and dispensing of a liquid specimen in a self-contained system. The present invention can be used in combination with numerous testing means for performing chemical, biochemical or biomedical qualitative or quantitative assays in the field of both clinical and hygiene testing.

Abstract: A rigid package or container for a catheter having catheter tube with a distal end and a proximal end, the proximal end being provided with a catheter outlet which may be used as a funnel or a connector. A main body is provided for holding the catheter, and a cap closes off the main body. A gel receptacle is positioned inside the main body, the gel receptacle being provided with a cavity for holding an amount of a lubricating agent. The gel receptacle includes a distal opening at a distal end thereof, and a proximal opening at a proximal end thereof, with the catheter tube extending therethrough. The gel receptacle is configured such that as the catheter is withdrawn therethrough a leading tip of the catheter is displaced so as to be immersed in the lubricating agent, thus automatically coating the leading tip.

Abstract: A package configured for storing and dispensing a tubular section of a urinary catheter includes a wall forming a spiral pattern on an interior surface of the package, a cavity, an outlet, a channel connecting the outlet and the cavity, and a by-pass flow path connected with the outlet. The spiral pattern extends from a central region of the package to an outer periphery of the package, with the spiral pattern of the wall forming a spiral space located between the wall and an adjacent section of the wall. The cavity is formed in the outer periphery of the package. The outlet is formed in the outer periphery of the package separate from the cavity.

Abstract: Intravenous access is achieved by introducing a catheter having a guidewire safety tip at its distal end. The safety tip can be advanced and retracted using a slider disposed over an access needle which is initially present in the catheter. After the catheter has been properly positioned, the access needle and guidewire may be removed so that the catheter is available for use.

Abstract: An organism paracentesis device comprises a first tube member and a second tube member. The first tube member comprises an injection tube filled with a medicament, a piston and a first syringe needle. The second tube member comprises a sampling tube and a second syringe needle. Both ends of the second syringe needle are in the form of syringe needle. Using one end of the second syringe needle to penetrate a cover of the sampling tube which is vacuumed, such that the second syringe needle's the other end which is penetrating into an organism will extract a sample from the organism because of the vacuumed sampling tube. The medicament filled in the injection tube is ejected both when the first and second syringe needles are penetrating into and pulled out of the organism, so as to avoid the cells of sampled organism being spread to other places.

Abstract: Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container.

Abstract: A container assembly is disclosed including an outer container, a hollow inner member, and a closure. The outer container has a closed bottom, an open top, and a sidewall extending therebetween. The hollow inner member is disposed within the outer container and has an inner surface defining at least one capillary channel. The inner member includes a first end adjacent to the open top of the outer container and has an outer periphery seated against the sidewall of the outer container. The closure has a proximal end and a distal end. The closure proximal end is seated at least partially within the first end of the inner member to seal the outer container and inner member and define a fluid collection chamber. The closure distal end defines a recessed area shaped to direct fluid under capillary action to the at least one capillary channel in the inner member.

Abstract: The present invention relates to injection devices for injecting a medicament from a cartridge (600) through a needle cannula (510). The injection device (100) includes an actuator (330, 360) for driving a piston driver (310) and includes an end of stroke limiter (341, 611). When the piston driver (310) is arrested by the end of stroke limiter (341, 611) a shielding driver (370) is automatically triggered to actively shift the needle cannula (510) into a shielded state. The injection device may include a fluid dispensing interruption mechanism that automatically interrupts fluid flow when the piston driver has moved a predetermined stroke length. The injection device may also include a single pre-stressed spring acting exclusively in a linear compression mode or exclusively in a torsion mode and adapted to sequentially drive the device to enable fully automatic operation. The invention also relates to a method of sterilizing a needle cannula assembly.

Abstract: A urine collection apparatus is disclosed to include an expandable bag connected to a urinary catheter, the bag being adapted to receive urine expelled from the person using the apparatus. The apparatus also has a check valve associated with the bag, which opens to admit gas to the interior of the bag to equilibrate the pressure within the bag with the pressure of the surrounding atmosphere whenever a partial vacuum occurs in the bag.

Abstract: A container for collecting a biological specimen is provided that includes a peripheral wall extending from a base. The container further includes a longitudinal tower disposed within the container. The tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another. In addition, the container include an insert disposed within the container opposite the base, the insert comprising at least a first opening and a second opening. The second opening provides access to the second chamber and is further configured to engage a specimen collecting device to leave a portion of the specimen collecting device within the second chamber. The first opening provides access to the first chamber and is further configured to receive a syringe therein for accessing the biological specimen. Associated systems and methods are also provided.

Abstract: A method for producing a membrane ring or test strip ring for a diagnostic test device includes an elongate strip that is divided into segments by cuts running transversely to the longitudinal direction of the strip, where the cuts are made only as far as a residual width of the strip so that a material bridge remains intact between the segments adjacent to the cuts (24). The strip is closed by bringing its ends together to form a ring where the cut edges of the cuts running towards the material bridges each enclose an acute angle (?). The ring is inserted into a support structure as a membrane ring or test strip ring for the test device.

Abstract: A collection device includes a base housing member having at least one chamber. A cover housing member has at least one aperture therein, and the cover housing member is configured to cover the base housing member such that the at least one aperture is positioned in fluid communication with the at least one chamber. The cover housing member includes a cartridge holding interface configured to releasably engage with a cartridge that is configured to cover and receive a fluid from the at least one chamber via the at least one aperture.