Patents by Inventor Mingde Xia

Mingde Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydro-cyclopentyl pyrazole cannabinoid modulators
    Patent number: 8119621
    Abstract: This invention is directed to a tetrahydro-cyclopentyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: February 21, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Fina Liotta, Mingde Xia, Michael P. Wachter, Scott A. Beers
  • Tetrahydro-1H-1,2,6-triaza-azulene cannabinoid modulators
    Patent number: 8012957
    Abstract: This invention is directed to a tetrahydro-1H-1,2,6-triaza-azulene cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: September 6, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mingde Xia, Fina Liotta, Michael P. Wachter
  • SUBSTITUTED 5-VINYLPHENYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS
    Publication number: 20110178148
    Abstract: This invention is directed to a cannabinoid modulator compound of formula (I): or a form thereof, and methods for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: April 4, 2011
    Publication date: July 21, 2011
    Inventors: Mingde XIA, Meng Pan, Michael P. Wachter
  • Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators
    Patent number: 7943653
    Abstract: This invention is directed to a cannabinoid modulator compound of formula (I): or a form thereof, and methods for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: May 17, 2011
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Mingde Xia, Meng Pan, Michael P. Wachter
  • BENZIMIDAZOLE DERIVATIVES USEFUL AS TRPM8 CHANNEL MODULATORS
    Publication number: 20110003800
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein R0, R1, R2, R3, R4 and a are defined herein.
    Type: Application
    Filed: June 10, 2010
    Publication date: January 6, 2011
    Inventors: Mark J. Macielag, Mingde Xia, Xiaoqing Xu
  • BENZIMIDAZOLE DERIVATIVES USEFUL AS TRPM8 CHANNEL MODULATORS
    Publication number: 20110003801
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein R0, R1, R2, R3, R4 and a are defined herein.
    Type: Application
    Filed: June 10, 2010
    Publication date: January 6, 2011
    Inventors: Michele C. Jetter, Mark J. Macielag, Mingde Xia, Xiaoqing Xu
  • HEXAHYDRO-CYCLOOCTYL PYRAZOLE CANNABINOID MODULATORS
    Publication number: 20100317633
    Abstract: This invention is directed to a hexahydro-cyclooctyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: August 26, 2010
    Publication date: December 16, 2010
    Inventors: Mingde Xia, Fina Liotta, Huajun Lu, Meng Pan, Michael P. Wachter, Mark J. Macielag
  • Hexahydro-cyclooctyl pyrazole cannabinoid modulators
    Patent number: 7851498
    Abstract: This invention is directed to a hexahydro-cyclooctyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: December 14, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mingde Xia, Fina Liotta, Huajun Lu, Meng Pan, Michael P. Wachter
  • TETRAHYDRO-CYCLOPENTYL PYRAZOLE CANNABINOID MODULATORS
    Publication number: 20100279991
    Abstract: This invention is directed to a tetrahydro-cyclopentyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: July 15, 2010
    Publication date: November 4, 2010
    Inventors: Fina Liotta, Mingde Xia, Michael P. Wachter, Scott A. Beers
  • Hexahydro-cyclooctyl pyrazole cannabinoid modulators
    Patent number: 7825151
    Abstract: This invention is directed to a hexahydro-cyclooctyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: November 2, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Mingde Xia, Fina Liotta, Huajun Lu, Meng Pan, Michael P. Wachter, Mark J. Macielag
  • Tetrahydro-2H-indazole pyrazole cannabinoid modulators
    Patent number: 7795294
    Abstract: This invention is directed to a tetrahydro-2H-indazole pyrazole cannabinoid modulator compound of formula (I): or a form thereof, wherein p, R1, R2 and Ar are as herein described and * represents a chiral center, and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: September 14, 2010
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Fina Liotta, Huajun Lu, Michael P. Wachter, Mingde Xia
  • Tetrahydro-cyclopentyl pyrazole cannabinoid modulators
    Patent number: 7790718
    Abstract: This invention is directed to a tetrahydro-cyclopentyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: September 7, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Fina Liotta, Mingde Xia, Michael P. Wachter, Scott A. Beers
  • TETRAHYDRO-PYRANOPYRAZOLE CANNABINOID MODULATORS
    Publication number: 20100069341
    Abstract: This invention is directed to a tetrahydro-pyranopyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: November 19, 2009
    Publication date: March 18, 2010
    Inventors: Fina Liotta, Huajun Lu, Michael P. Wachter, Mingde Xia
  • Cold Menthol Receptor Antagonists
    Publication number: 20100048589
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein A, B, L, Q, R1, R2, and R3 are defined herein.
    Type: Application
    Filed: August 11, 2009
    Publication date: February 25, 2010
    Inventors: Raymond W. Colburn, Scott L. Dax, Christopher M. Flores, Donald W. Ludovici, Jay M. Matthews, Mingde Xia, Xiaoqing Xu, Mark A. Youngman, Bin Zhu
  • Cold Menthol Receptor Antagonists
    Publication number: 20100048619
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein A, L, R1, R2, R4 and R5 are defined herein.
    Type: Application
    Filed: August 11, 2009
    Publication date: February 25, 2010
    Inventors: Raymond W. Colburn, Scott L. Dax, Christopher M. Flores, Donald W. Ludovici, Mingde Xia, Xiaoqing Xu, Mark A. Youngman, Bin Zhu
  • METHOD FOR TREATING CB2 RECEPTOR MEDIATED PAIN
    Publication number: 20090215850
    Abstract: The present invention is directed to a method for treating, ameliorating or preventing CB2 receptor mediated pain in a subject in need thereof comprising administering to the subject an effective amount of a compound of formula (I): or a form thereof, wherein X1R1, X2R2, X3R3, X4R4 and X5R5 are as defined herein.
    Type: Application
    Filed: February 27, 2008
    Publication date: August 27, 2009
    Inventors: Mingde Xia, Mark J. Macielag, Christopher M. Flores, Kevin Paul Pavlick
  • HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS
    Publication number: 20090197886
    Abstract: This invention is directed to a hexahydro-cycloheptapyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: April 7, 2009
    Publication date: August 6, 2009
    Inventors: Fina Liotta, Mingde Xia, Huajun Lu, Meng Pan, Michael P. Wachter
  • Tetrahydrothiopyrano pyrazole cannabinoid modulators
    Patent number: 7524964
    Abstract: The invention relates to a CB modulator compound of Formula (I) or a pharmaceutically acceptable form thereof and a method for use in treating, ameliorating or preventing a CB receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: April 28, 2009
    Assignee: Janssen Pharmaceutica NV
    Inventors: Fina Liotta, Huajun Lu, Mingde Xia, Michael P. Wachter
  • TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS
    Publication number: 20090099143
    Abstract: This invention is directed to a tetrahydro-indazole cannabinoid modulator compound of formula I: and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: October 8, 2008
    Publication date: April 16, 2009
    Inventors: Bharat Lagu, Fina Liotta, Meng Pan, Michael P. Wachter, Mingde Xia Xia
  • SUBSTITUTED 5-VINYLPHENYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS
    Publication number: 20090048235
    Abstract: This invention is directed to a cannabinoid modulator compound of formula (I): or a form thereof, and methods for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: August 11, 2008
    Publication date: February 19, 2009
    Inventors: Mingde Xia, Meng Pan, Michael P. Wachter