Patents by Inventor Mingde Xia

Mingde Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydro-indazole cannabinoid modulators
    Patent number: 7452997
    Abstract: This invention is directed to a tetrahydro-indazole cannabinoid modulator compound of formula I: and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: November 18, 2008
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Bharat Lagu, Fina Liotta, Meng Pan, Michael P. Wachter, Mingde Xia Xia
  • METHOD FOR TREATING CB2 RECEPTOR MEDIATED PAIN
    Publication number: 20080234347
    Abstract: The present invention is directed to a method for treating, ameliorating or preventing CB2 receptor mediated pain in a subject in need thereof comprising administering to the subject an effective amount of a compound of formula (I): or a form thereof, wherein X1R1, X2R2, X3R3, X4R4 and X5R5 are as defined herein.
    Type: Application
    Filed: February 27, 2008
    Publication date: September 25, 2008
    Inventors: Mingde Xia, Mark J. Macielag, Christopher M. Flores, Kevin Paul Pavlick
  • TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS
    Publication number: 20080085899
    Abstract: The invention relates to a CB modulator compound of Formula (I) or a pharmaceutically acceptable form thereof and a method for use in treating, ameliorating or preventing a CB receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: December 7, 2007
    Publication date: April 10, 2008
    Inventors: Fina Liotta, Huajun Lu, Mingde Xia, Michael Wachter
  • Hexahydro-Cyclooctyl Pyrazole Cannabinoid Modulators
    Publication number: 20080076814
    Abstract: This invention is directed to a hexahydro-cyclooctyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: March 20, 2007
    Publication date: March 27, 2008
    Inventors: Mingde Xia, Fina Liotta, Huajun Lu, Meng Pan, Michael P. Wachter, Mark J. Macielag
  • Hexahydro-Cycloheptapyrazole Cannabinoid Modulators
    Publication number: 20080070968
    Abstract: This invention is directed to a hexahydro-cycloheptapyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: March 20, 2007
    Publication date: March 20, 2008
    Inventors: Fina Liotta, Mingde Xia, Huajun Lu, Meng Pan, Michael P. Wachter, Mark J. Macielag
  • TETRAHYDRO-2H-INDAZOLE PYRAZOLE CANNABINOID MODULATORS
    Publication number: 20080058313
    Abstract: This invention is directed to a tetrahydro-2H-indazole pyrazole cannabinoid modulator compound of formula (I): or a form thereof, wherein p, R1, R2 and Ar are as herein described and * represents a chiral center, and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: February 13, 2007
    Publication date: March 6, 2008
    Inventors: Fina Liotta, Huajun Lu, Michael Wachter, Mingde Xia
  • TETRAHYDRO-1H-1,2,6-TRIAZA-AZULENE CANNABINOID MODULATORS
    Publication number: 20070259853
    Abstract: This invention is directed to a tetrahydro-1H-1,2,6-triaza-azulene cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: March 27, 2007
    Publication date: November 8, 2007
    Inventors: Mingde Xia, Fina Liotta, Michael Wachter
  • Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators
    Publication number: 20070254911
    Abstract: This invention is directed to a tetrahydro-pyrazolo[3,4-c]pyridine cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: March 23, 2007
    Publication date: November 1, 2007
    Inventors: Mingde Xia, Meng Pan, Fina Liotta, Michael Wachter
  • METHOD OF USE FOR SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS
    Publication number: 20070219245
    Abstract: The present invention is directed to a method for use of substituted dipiperidine compounds of Formula (I) or a salt, isomer, prodrug, metabolite or polymorph thereof, which are CCR2 antagonists, for preventing, treating or ameliorating syndromes, disorders or diseases related to CCR2 activation in a subject in need thereof.
    Type: Application
    Filed: March 13, 2007
    Publication date: September 20, 2007
    Inventors: Cuifen Hou, Yin Liang, Keith T. Demarest, Druie E. Cavender, Michael P. Wachter, Mingde Xia
  • SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS
    Publication number: 20070197590
    Abstract: Substituted dipiperidine compounds of Formula (I) or a form thereof, which are CCR2 antagonists and are useful in preventing, treating or ameliorating CCR2 mediated inflammatory syndromes, disorders or diseases in a subject in need thereof.
    Type: Application
    Filed: January 31, 2007
    Publication date: August 23, 2007
    Inventors: Duane DeMong, Mingde Xia, Scott Pollack, Xiaoping Zheng, James Brackley, Michael Wachter, Druie Cavender, Keith Demarest
  • Tetrahydro-cyclopentyl pyrazole cannabinoid modulators
    Publication number: 20070191362
    Abstract: This invention is directed to a tetrahydro-cyclopentyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: September 22, 2006
    Publication date: August 16, 2007
    Inventors: Fina Liotta, Mingde Xia, Michael Wachter, Scott Beers
  • Substituted 3-amido-tetrahydro-indazolyl cannabinoid modulators
    Publication number: 20070117857
    Abstract: This invention is directed to a substituted 3-amido-tetrahydro-indazolyl cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: September 18, 2006
    Publication date: May 24, 2007
    Inventors: Fina Liotta, Michael Wachter, Mingde Xia
  • SUBSTITUTED 5-HETEROARYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS
    Publication number: 20070117858
    Abstract: This invention is directed to a substituted 5-heteroaryl-1-phenyl-pyrazole cannabinoid modulator compound of formula (I): or a form thereof, and methods for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: November 16, 2006
    Publication date: May 24, 2007
    Inventors: Mingde Xia, Fina Liotta, Meng Pan, Michael Wachter, Huajun Lu
  • Tetrahydrothiopyrano pyrazole cannabinoid modulators
    Publication number: 20060223798
    Abstract: The invention relates to a CB modulator compound of Formula (I) or a pharmaceutically acceptable form thereof and a method for use in treating, ameliorating or preventing a CB receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: March 16, 2006
    Publication date: October 5, 2006
    Inventors: Fina Liotta, Huajun Lu, Mingde Xia, Michael Wachter
  • Tetrahydro-pyridinyl pyrazole cannabinoid modulators
    Publication number: 20060089378
    Abstract: This invention is directed to a tetrahydro-pyridinyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: October 18, 2005
    Publication date: April 27, 2006
    Inventors: Mingde Xia, Meng Pan, Michael Wachter, Fina Liotta
  • Substituted dipiperidine CCR2 antagonists
    Publication number: 20060069123
    Abstract: Substituted dipiperidine compounds of Formula (I) or a salt, isomer, prodrug, metabolite or polymorph thereof, which are CCR2 antagonists and are useful in preventing, treating or ameliorating CCR2 mediated inflammatory syndromes, disorders or diseases in a subject in need thereof.
    Type: Application
    Filed: September 12, 2005
    Publication date: March 30, 2006
    Inventors: Mingde Xia, Michael Wachter, Meng Pan, Duane DeMong, Scott Pollack
  • Tetrahydro-indazole cannabinoid modulators
    Publication number: 20050228034
    Abstract: This invention is directed to a tetrahydro-indazole cannabinoid modulator compound of formula I: and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or disease.
    Type: Application
    Filed: March 23, 2005
    Publication date: October 13, 2005
    Inventors: Bharat Lagu, Fina Liotta, Meng Pan, Michael Wachter, Mingde Xia